Doctor insights on:
Rarely is there a single genotype, usually multiple variants exist. Read this for an idea:
http://www. Ncbi. Nlm. Nih. Gov/pubmed/10638211 ...Read more
↑ed cholesterol (in blood); a specific fat molecule made by every animal cell on planet, part of every animal cell membrane, enables membrane flexibility, cells to change shape, animals to move. Look it up ("cholesterol molecule" works best) on Google & images. Additionally, for most people Hi-Chol foods ↓es measured LDL particles while ↓Chol foods ↑LDL; driving ...Read more
See a Lipidologist: Familial hypercholesterolemia (fh) is a genetic disorder causing decreased clearance of LDL from blood. Most patients get a defective gene from on parent causing heterozygous fh (about 1 in 500 children). Rarely, genes from both parents are defective giving homozygous fh (1 in 1, 000, 000). Lipidologists specialize in managing fh patients. Check http://www. Learnyourlipids. Com to find a lipidologist. ...Read more
Tests: You should the discuss the matter with your doctor as it may require performing multiple tests, in succession on you and your family members. The first one would be to have blood lipids tested in fasting state and depending on those results, other tests and tests on family members may be needed. Confirmation of the diagnosis may require molecular testing. ...Read more
Lipid testing: A simple blood test will help your doctor determine whether you have a genetic disorder that makes it difficult for your body to maintain normal levels of cholesterol and triglycerides. ...Read more
Blood work: Blood work will give you a pretty good clue because familial hypercholesterolemia is usually pretty bad - but an even better way is to ask your relatives! ...Read more
YES: Familial hypercholesterolemia can be very potentially serious. A full evaluation of what you lipid profile, family history, longevity of family members, diseases in the fh are all important for your future health and will guide you as to what lifestyle changes you must make it quality of life and longevity. Get ye to a good primary care internist. ...Read more
Yes: See a board certified lipidologist.Get a more detailed answer ›
May be: Essentially it means in your lipid profile it's the Cholesterol or LDL is elevated. It may be genetic or due to lifestyle, either way it needs to be treated, and best that works are the Statins (Lipitor, (atorvastatin) creator, simvastatin). Also diet and excercise. Important to bring to below normal since it increases your risk of Heart disease or Coronary diseases. ...Read more
Yes: Ldl liver receptors normally grab onto the cholesterol in the blood stream, dump the cholesterol into the bile and thus lower the blood cholesterol level. In familial hypercholesterolemia there is a much lower number of these receptors so the blood cholesterol level is very high allowing the cholesterol to be deposited in blood vessels causing the deposits leading to heart attacks and strokes. ...Read more
Screen lipid panel: Hi Familial hypercholesterolemia is a defect in the LDL receptor gene. You have 2 copies of the gene: 1 from your mom & 1 from your dad. If you have 1 good copy and 1 mutant copy, you're heterozygous and have elevated LDL and premature atherosclerosis. If you have 2 bad copies, you're homozygous recessive, and have very aggressive atherosclerosis at a young age. There is gene testing. ...Read more
Yolk: The yolk is loaded with cholesterol. One egg has 186 mg of cholesterol and that's 86% of your daily recommended cholesterol in-take. So, you can eat 1 egg a day and little else that contains cholesterol. It's up to you. ...Read more
Most Do: Familial hypercholesterolemia is the most common genetic disorder involving choleterol levels. If a patient has an LDL cholesterol level above 200 he/she has familial hypercholesterolemia. It is transmitted in a way that each child has a 50/50 chance of inheriting this. On a microscopic level there is increased liver fat in all of these patients, it just may not show up on blood tests. ...Read more
Physician is better: Genetic counselors are master's trained individuals trained to collect and interpret family histories but with little clinical experience. You should see your family practitioner or internist and have a lipid profile. Familial hypercholesterolemia would be indicated by a very high cholesterol, and your family history may show other people with early heart attacks/strokes who need lipid studies. ...Read more
Is it possible that infants with homozygous familial hypercholesterolemia develop xanthomas or xanthelasmas?
Yes: There are plenty of other possible causes of xanthomas in kids, elbows ; butt. Especially if they're on the knees, some bloodwork would be a great idea. ...Read more
Can infants with homozygous familial hypercholesterolemia develop xanthomas or xanthelasmas? What are your expert opinions?
Gene dose effect: Hi. Is the infant homozygous or heterozygous for FH? Homozygotes can develop tendon xanthomata or xanthelasma in childhood. Many heterozygotes don't ever get xanthomata. If the infant is a homozygote, he/she has a tough road ahead; heterozygotes too, but very tough for homozygotes. Good luck! ...Read more
Do you have to have cardiovascular diseases if you have familial hypercholesterolemia? What are all the symptoms?
Familial: Hypercholesterolemia is a predisposing factor for cardiovascular disease together with hypertension, diabetes, smoking and other factors. This is not to say that all people with this condition will develop cardiovascular disease. Treatment of the condition in different form will reduce the risk significantly. Talk to your doctor and know your risk and take action. ...Read more
I wasn't told I had high cholesterol 3 years ago and was told I have high cholesterol now as do my parents. Familial hypercholesterolemia? HDL 104!
I wear a Fitbit & my heart rate is 49-54bpm, I’m worried! 163cm & weigh 65kg. I do some exercise. Familial hypercholesterolemia- last levels 7.2?
No big deal: The thing isn't accurate anyway. And even if your pulse runs this low -- count it -- it's probably just you if you feel well. ...Read more
Would an LDL level of 172 at 28 suggest familial hypercholesterolemia? No family hx of heart disease. All grandparents lived well in to 70s & 80s.
Yes: Despite all the talk about "healthy living" and so forth, your LDL level is mostly genetic and if you need meds, you need meds -- remember that other lifestyle factors, especially smoking and fitness habits are under your control. In true familial hypercholesterolemia, the illness that kills folks around their 20's by itself, levels are much higher. Your physician's your best guide. ...Read more
I have familial hypercholesterolemia but want to put on muscle in the gym. Are there any supplements I can take that won't effect my statin treatment?
Sure: I'm really glad you're getting the cholesterol treated. Before statins, one of my colleagues died at your age from this illness. For muscling up, creatine and an electronic muscle stimulator (if your phsician is okay with the latter) are your best friends. Other supplements are less likely to help. Avoid steroids -- I've been around gyms for decades & most who try them are sorry. Cheers. ...Read more
Can you get a Stroke early in age from familial hypercholesterolemia. I've had known untreated high cholesterol since age 19. History of brain lesions?
Yes: Unfortunately familial hypercholesterolemia does put you at an increased risk for stroke and heart attack, but these risks can be decreased with cholesterol-lowering drugs. I can't comment on the brain lesions without seeing them, but it's possible that they're strokes. I hope you're following with a doctor about your cholesterol and cholesterol lowering meds. Good luck! ...Read more