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Doctor insights on: Hydroxyurea Chronic Lymphocytic Leukemia

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Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

CLL: Cll is a clonal disorder (cancer) of the white blood cells (specifically lymphocytes) in the blood (= -emia part). Other leukemias include cml, aml, all, etc. Cll is often diagnosed by flow cytometry on peripheral blood. Additional studies may include ct scans and bone marrow biopsy. One staging system is rai 0 to iv. Treatment ranges from observation (rai 0-1) to various tx individualized to pt. ...Read more

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How common is fatigue with stage i chronic lymphocytic leukemia?

How common is fatigue with stage i chronic lymphocytic leukemia?

About 10-20%: Fatigue is nonspecific. Here we talked about extreme fatigue not very common. Most people with cll, especially at early stage, are asymptomatic. About 10-20% people will experience so-called b symptoms (fatigue, fever, night sweat, or weight loss). This number could go higher as disease progresses, but no linear relationship. ...Read more

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What're the effects of chronic lymphocytic leukemia?

See below: Cll is form of blood cancer, usually a slowly progressing one. It may cause fever, enlarged lymph nodes, weight loss, anemia etc. See this site for more info. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001559/. ...Read more

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How to determine chronic lymphocytic leukemia stages?

Your oncologist can: Ask your treating doctor. The stages of cll are based on the extent of disease which requires both blood tests as well as physical exam and ct scans of the chest and abdomen to look for lymph node enlargement and or splenomegaly. ...Read more

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What causes people to get chronic lymphocytic leukemia?

What causes people to get chronic lymphocytic leukemia?

Mostly unknown: Cll affects older white men more that other parts of the population and the cause is unknown in most cases. Exposure to certain herbicides and insecticides, including agent orange used during the vietnam war, have been linked to an increased risk. For more information consult: http://www.Mayoclinic.Com/health/chronic-lymphocytic-leukemia/ds00565/dsection=risk. ...Read more

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What is the definition or description of: chronic lymphocytic leukemia?

CLL: Simplisticly it is an overgrowth of lymphocytes. Since these cells are usually slow growing the disease tends to progress at a relatively slow rate compared to other types of leukemias and in general may take years to begin to harm a patient. Treatment is usually withheld until the patient becomes symptomatic. ...Read more

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What're the chances of someone inheriting chronic lymphocytic leukemia?

What're the chances of someone inheriting chronic lymphocytic leukemia?

Rare: There have been familial cases reported and my partner and i had a brother and a sister. The brother has never required therapy yet but the sister did. Mayo clinic is doing a study on familial cases. Mainly taking blood and studying it. It is an ongoing study so the results are not available yet. Hope this helps. ...Read more

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What is the definition or description of: chronic lymphocytic leukemia ivgh?

A test 2 assess risk: The correct name is igvh mutational status assay. This is a gene test performed only on leukemic cells of patients with cll to assess risk of progression, and death from cll. The readout is either mutated (which is favorable) or unmutated (unfavorable). Igvh mutations happen during the normal generation of antibodies in white cells. ...Read more

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Chronic sinusitis and chronic lymphocytic leukemia--not good together?

Low IgG?: agreed. Frequent bacterial infection associated with CLL may be due to hypogammaglobulinemia (Low amount of antibodies, also called low IgG). That's treatable with monthly infusion of IVIG (intravenous immune globulin). Discuss with hematologist/oncologist. ...Read more

Dr. Julio Hajdenberg
87 doctors shared insights

Cll (Definition)

Chronic lymphocytic leukemia, or CLL, is the most common blood and bone marrow cancer in older adults. It arises in lymphocytes, blood cells that are part of the immune system. Chronic refers to its ...Read more


Dr. Margaret Shipp
232 doctors shared insights

Hydroxyurea (Definition)

Hydroxyurea ...Read more