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Doctor insights on: Hydroxyurea

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Dr. Margaret Shipp
235 Doctors shared insights

Hydroxyurea (Overview)

Hydroxyurea is a cancer agent.


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What does small amounts of hydroxyurea in blood mean?

What does small amounts of hydroxyurea in blood mean?

Treatment/exposure: Hydroxyurea is a drug used to treat certain blood disorders, some cancers, and HIV disease. If you not on this medicine you may be exposed to it in other ways such as handling it for a loved one. If neither is the case, please consult a healthcare provider asap.

Dr. Margaret Shipp
235 Doctors shared insights

Hydroxyurea (Overview)

Hydroxyurea is a cancer agent.


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Can you tell me about hydroxyurea 500 mg availability?

Can you tell me about hydroxyurea 500 mg availability?

Available: 500mg oral tab of hydroxyurea is available in US. Is that your question? . The dosing of hydroxyurea, however, should be monitored by a doctor.

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Can we use hydroxyurea with sickle cell anemia patient?

Can we use hydroxyurea with sickle cell anemia patient?

HU in sickle cell: Certain patients with sickle cell can be helped by Hydroxyurea (hu). Initially, Hydroxyurea was thought to increase fetal hemoglobin levels (not carrying the sickle cell mutation), but more recently, hu has been shown to decrease high white blood cell counts which can lead to vaso-occlusive crises. Talk with your hematologist to see if hu is right for you.

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Before 2 yrs old is Hydroxyurea safe for a e beta thallassemia child? She needs transfusion after every 45 days. Pls advice...

Before 2 yrs old is Hydroxyurea safe for a e beta thallassemia child? She needs transfusion after every 45 days. Pls advice...

Studies have shown…: Benefits from use of hydroxyurea, even in children aged 2.6 and 3 years. Because of the child's age, I'm going to refer your question to a pediatric hematologist/oncologist.

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Can muscle cramping be a side effect of taking hydroxyurea?

Can muscle cramping be a side effect of taking hydroxyurea?

Not commonly: It's not a common symptom of Hydroxyurea but Hydroxyurea can cause nausea, vomiting, diarrhea and renal impairment which can cause muscle cramps. Not sure you have the above symptoms.

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How long can a patient take hydroxyurea for primary essential thrombocytosis?

As long as it works: This medication has been studied for a long time. There has been no reported cases of secondary cancers directly related to hydrea (hydroxyurea). It just needs to be monitored, as you know. Hope this helps.

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What are the effects of a sickle cell patient using hydroxyurea in the long term?

What are the effects of a sickle cell patient using hydroxyurea in the long term?

Side Effects: There are some serious, but rare, side effects with hydroxyurea, including secondary leukemia, pulmonary fibrosis, pancreatitis, and peripheral neuropathy, or damage to the nerves. Discuss the benefits of decreasing the severity and length of the sickle cell attacks, and the risk of rare side effects as above.

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How long can you safely take hydrea (hydroxyurea)?

How long can you safely take hydrea (hydroxyurea)?

Risks vs. Benefits: Hydroxyurea is used to treat sickle cell anemia and some leukemias (blood cancers). As will most medications, there is no official time limit. A medicine that is helpful, is doing a good job, has no equal alternative, and thus is needed, can be used until it is no longer needed. The doctor can explain the risks of "not treating" and of drug side effects, versus the benefits of using hydroxyurea.

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What is hydrea (hydroxyurea) usually used to treat?

Many diseases: This antimetabolite has been used for >100yrs in treating benign & malignant conditions including sickle cell disease, essential thrombocytosis, p. Vera, cml, prostate cancer, psoriasis, & even aids.

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Can you tell me about hydroxyurea 500 mg availability?

Available: 500mg oral tab of hydroxyurea is available in US. Is that your question? . The dosing of hydroxyurea, however, should be monitored by a doctor.

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My dad has to take hydroxyurea. Why?

My dad has to take hydroxyurea. Why?

Blood disorder: My suspicion is that he has a blood disorder called a myeloproliferative neoplasm. His bone marrow is probably making too many of one or more cells. This medication treats this to prevent any complications of over production. Hope this helps.

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Are hydroxyurea and clexane usually given together?

Are hydroxyurea and clexane usually given together?

Depends on situation: What is the reason Hydroxyurea is being given? One use of Hydroxyurea is to treat resistant chronic myelocytic leukemia (cml, a cancer of white blood cells). Cancers increase risk of blood clots (dvt), which can be treated w enoxaparin (clexane) in such a case, both would be given. If in hospital, meds like enoxaparin can be used to prevent dvt. Other scenarios exist in which both could be used.

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Is Hydroxyurea allowable /applicable for a 1 yr e beta thallassemia baby? Pls advice..

Is Hydroxyurea allowable /applicable for a 1 yr e beta thallassemia baby? Pls advice..

Unclear: I don't see any reliable information on using hydroxyurea under the age of 2 for decreasing transfusion needs in beta thalassemia babies.

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What does small amounts of hydroxyurea in blood mean?

Treatment/exposure: Hydroxyurea is a drug used to treat certain blood disorders, some cancers, and HIV disease. If you not on this medicine you may be exposed to it in other ways such as handling it for a loved one. If neither is the case, please consult a healthcare provider asap.

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Can hair relaxers cause a problem if taking hydroxyurea?

I do tink so: Drug interactions there are no data on concomitant use of Hydroxyurea with other drugs in humans.

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My mom was prescribed mylocel (hydroxyurea). How does that work?

Antimetabolite: Mylocel, or hydroxyurea, is a form of chemotherapy that works to lower blood counts particularly in patients with leukemia such as chronic myelogenous leukemia and myeloproliferative disorders including polycythemia rubra vera and essential thrombocytosis. Short term side effects may include nausea, hair loss, diarrhea, poor appetite, and nail thickening. Long term effects may include infertility.

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Pls advice about the standard /perfect age to taking Hydroxyurea of a e beta thallassemia child?

1 month old: Homozygous hemoglobin E disease (genetic; inherited from both parents) gives mild beta thalassemia & anemia & mildly enlarged spleen; probably doesn't need treatment. Hgb E beta thalassemia disease (E from 1 parent, beta thal from the other): severe incurable disease. Hydroxyurea safe in infants. My guess: start early as possible after 1 mo old. Do discuss this with your pediatric hematologist.

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"Hydroxyurea may affect fertility (ability to have children), whether a man or a woman."Please advice..

"Hydroxyurea may affect fertility (ability to have children), whether a man or a woman."Please advice..

Chemotherapy: It is a chemotherapy drug (a mild one, that doesn't have severe side effects, once it has been checked, worries about it lowering blood counts too much are not much). It does lower sperm quality and that effect can last after it is stopped. Http://www. Ncbi. Nlm. Nih. Gov/pubmed/17316339

Dr. Jan Lei Iwata
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Dr. Scott Keith
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