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Plaquenil (hydroxychloroquine): Toxicity can show hearing & hair loss, convulsions, liver damage.
Not a pain med: Many people with mild rheumatoid arthritis (RA) or lupus respond to hydroxychloroquine. It is not a pain medication. The key is to have the rheumatologist assess whether the Hydroxychloroquine is adequately controlling the RA to prevent progression as progression can lead to deformity. If the diagnosis is lupus, control needs to be measured also.
Can anyone please tell me do you gain weight taking hydroxychloroquine at 200mg a day as I am a healthy eater thank you?
Not likely cause: Weight gain is not a side effect of hydroxychloroquine. Actually, weight loss has been reported.
Nothing safer: Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. So other meds like Imuran and CellCept (mycophenolate mofetil) also reduce flares, but also increases infection.
Yes: At least 100% of my lupus patients have tried it and 75% of the RA patients.
Plaquenil (hydroxychloroquine): Hydroxychloroquine, an anti-malarial, is used to treat RA and SLE. Although called "immune-suppresive" it does not have a powerful effect on the immune system. We are still understanding how it works and in general it regulates the communication of immune cells / lymphocytes. More precisely, it reduces toll-like receptors signaling, which reduces immune cell activation and inflammation.
For what treatment?: Plaquenil (hydroxychloroquine) or Hydroxychloroquine is used to treat multiple different conditions. What would be appropriate to substitute would depend on how it is being used to treat your disease.
HO-Q: Given at the appropriate dose 6.5mg-6mg/kg of body weight, the drug as few if any, cognitive effects. I have not seen one case similar to what you are decribing. Since you are on, most likely several meds, it may be others. Also, many patients are taking this drug for potentially serious diseases. This by itself can affect mood.See 2 more doctor answers
Yes: Hydroxychloroquine-associated retinopathy is more common based on a higher cumulative dosage. For standard doses, your risk will increase after 5 years of use, but if you are using a higher dose or are petite that will affect the timeline. Your rheumatologist and/or ophthalmologist should be able to give you more guidance.
Plaquenil (hydroxychloroquine): Plaquenil (hydroxychloroquine) has many side effects. Some common ones include dizziness, abdominal pain, headache, nausea, diarrhea, itching, and sensitiviy to sun. More serious side effects which are more rare include certain types of anemia, muscle pain, and liver problems, among others. Despite the fact that what you describe is not officially under it's side effect profile, it still could be causing your symptoms.
Unlikely: Its unlikely but regular examination by an opthamologist is recommended to watch for any changes.See 1 more doctor answer
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