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Doctor insights on: Hydroxychloroquine

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What is hydroxychloroquine medicine used for?

What is hydroxychloroquine medicine used for?

Antimalarial: Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments.

Dr. Patricia Foster
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What is hydroxychloroquine medicine used for?

What is hydroxychloroquine medicine used for?

Hydroxychloroquone: Malaria treatment/prophylaxis, lupus, rheumatoid arthritis. Get eye exam (retina) at least yearly if using for prolonged period if time (> 2-3 months).

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What is hydroxychloroquine for n what is in it?

What is hydroxychloroquine for n what is in it?

Medication: That is used as antimalaria and has also use in inflammatory arthritis with adverse effects listed

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What is the average dosage for hydroxychloroquine?

What is the average dosage for hydroxychloroquine?

Plaquenil (hydroxychloroquine): Each tablet is 400mg. Taken as 2 tablets per week for malaria prevention, 1 tablet once daily for rheumatoid arthritis, and 1 tablet twice daily for lupus.

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What happens if you take too much of hydroxychloroquine?

What happens if you take too much of hydroxychloroquine?

Plaquenil (hydroxychloroquine): Toxicity can show hearing & hair loss, convulsions, liver damage.

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Has anyone ever taken pain medication hydroxychloroquine?

Has anyone ever taken pain medication hydroxychloroquine?

Not a pain med: Many people with mild rheumatoid arthritis (RA) or lupus respond to hydroxychloroquine. It is not a pain medication. The key is to have the rheumatologist assess whether the Hydroxychloroquine is adequately controlling the RA to prevent progression as progression can lead to deformity. If the diagnosis is lupus, control needs to be measured also.

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Dangers of plaquenil (hydroxychloroquine)?

Dangers of plaquenil (hydroxychloroquine)?

Low risk: Potential Plaquenil (hydroxychloroquine) side effects include GI intolerance, itching, rash, muscle weakness and eye inflammation (retinopathy). All of these risks are very low and the benefits of Plaquenil (hydroxychloroquine) will far out weight the risks.

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What do hydroxychloroquine sulphate tablets do?

Several things: Hydroxychloroquin is an antimalarial drug that has been found useful in treating Rheumato9id Arthritis, Lupus Erythematosis, Discoid Lupus, and in addition in some people induce remission. It does have side effects and need regular eye exams, but in general is well tolerated.

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What can substitute plaquenil (hydroxychloroquine)?

Nothing safer: Plaquenil is also known as hydroxychloroquine, so the parent drug Chloroquine can be substituted. But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. So other meds like Imuran and CellCept (mycophenolate mofetil) also reduce flares, but also increases infection.

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Do you think plaquenil (hydroxychloroquine) is safe?

Yes: At least 100% of my lupus patients have tried it and 75% of the RA patients.

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What does hydroxychloroquine sulfate do to our body?

What does hydroxychloroquine sulfate do to our body?

Plaquenil (hydroxychloroquine): Hydroxychloroquine, an anti-malarial, is used to treat RA and SLE. Although called "immune-suppresive" it does not have a powerful effect on the immune system. We are still understanding how it works and in general it regulates the communication of immune cells / lymphocytes. More precisely, it reduces toll-like receptors signaling, which reduces immune cell activation and inflammation.

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What could substitute for plaquenil (hydroxychloroquine)?

For what treatment?: Plaquenil (hydroxychloroquine) or Hydroxychloroquine is used to treat multiple different conditions. What would be appropriate to substitute would depend on how it is being used to treat your disease.

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Taking hydroxychloroquine and showing severe mood changes?

Taking hydroxychloroquine and showing severe mood changes?

HO-Q: Given at the appropriate dose 6.5mg-6mg/kg of body weight, the drug as few if any, cognitive effects. I have not seen one case similar to what you are decribing. Since you are on, most likely several meds, it may be others. Also, many patients are taking this drug for potentially serious diseases. This by itself can affect mood.

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What are side efffects of plaquenil (hydroxychloroquine)?

What are side efffects of plaquenil (hydroxychloroquine)?

Plaquenil (hydroxychloroquine): Side effects are muscle weakness, twitching, incoordination, blurred vision, bleeding, confusion, seizures, GI upset, hair loss.

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Can prolonged use of hydroxychloroquine cause retinopathy?

Can prolonged use of hydroxychloroquine cause retinopathy?

Yes: Hydroxychloroquine-associated retinopathy is more common based on a higher cumulative dosage. For standard doses, your risk will increase after 5 years of use, but if you are using a higher dose or are petite that will affect the timeline. Your rheumatologist and/or ophthalmologist should be able to give you more guidance.

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Can plaquenil (hydroxychloroquine) give you a heavy feeling?

Can plaquenil (hydroxychloroquine) give you a heavy feeling?

Plaquenil (hydroxychloroquine): Plaquenil (hydroxychloroquine) has many side effects. Some common ones include dizziness, abdominal pain, headache, nausea, diarrhea, itching, and sensitiviy to sun. More serious side effects which are more rare include certain types of anemia, muscle pain, and liver problems, among others. Despite the fact that what you describe is not officially under it's side effect profile, it still could be causing your symptoms.

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Will prolonged use of hydroxychloroquine lead to retinopathy?

Will prolonged use of hydroxychloroquine lead to retinopathy?

Unlikely: Its unlikely but regular examination by an opthamologist is recommended to watch for any changes.

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