Doctor insights on:
Hydrea Allergy In Children
Yes: In the treatment of sickle-cell disease, hydroxycarbamide increases the concentration of fetal hemoglobin. The precise mechanism of action is not yet clearbut it seems to activate of gammaglobin synthesis necessary for fetal hemoglobin. This stops the rapidly growing cells that turn into sickle cells. ...Read more
Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more
ET: When deciding whether to recommend hydrea, (hydroxyurea) the md takes into account patient's age, underlying cardiovascular risk factors, ; prior history of blood clots. The number of platelets is irrelevant if a patient is otherwise healthy. I have plenty of patients with platelet counts around 1 million. Look for an article from blood journal called "how I treat essential thrombocythemia" for a good summary. ...Read more
Risks vs. Benefits: Hydroxyurea is used to treat sickle cell anemia and some leukemias (blood cancers). As will most medications, there is no official time limit. A medicine that is helpful, is doing a good job, has no equal alternative, and thus is needed, can be used until it is no longer needed. The doctor can explain the risks of "not treating" and of drug side effects, versus the benefits of using hydroxyurea. ...Read more
No: Truly homeopathic "medications" are made by repeated dilutions, so that the ingredient is not really in the medication anymore (just the "essence" of it remains). That means there is no active ingredient left to cause any benefit. However, that also implies that the homeopathic "medicine" should be pretty harmless, unless some other non-homeopathic ingredients were added. ...Read more
Discuss it with Dr: Fatigue is subjective? Age? How much fatigued? What is your hemoglobin (red cell), white cell and platelet counts? Hydroxyurea is used to reduce the platelet number and might reduce as a side effect the hemoglobin and/or the white cells. There are newer mediations which might be used. Go and discuss the problem with your oncologist, who knows you better than me! Do not hesitate to go and ask. ...Read more
I have sickle cell anemia and everyday iam constantly in pain and feel tired. I have been taking hydrea (hydroxyurea) but is there anything else I could do?
My sympatrhy: Unfortunately no other treatments are yet available. ...Read more
I am on hydrea (hydroxyurea). I have an increase wbc, pain across my lower back, fatigue, occa. Sharp pain in my abdomen, nausea, and chills. Is this an emergency?
Yes: Go to er if this is new symptom. ...Read more
Exposure + Genes: One needs both a genetic component and "exposure" to a said allergen to develop an allergy. There is a growing support over the past 20 years, that growing up in an environment which is "too clean" can also lead to development of allergies down the road. Either way, allergies are on the rise. ...Read more
Nut allergy: Maybe. Your children may have inherited genes from you that make them more likely to develop an allergy, but they do not inherit a specific allergy to a food e.g. Nuts. The children have to be exposed to food proteins in the diet, before an allergy can develop. Once one develops an allergy then they are always allergic and need proper medical attention to prevent severe problems. ...Read more
Allergy tests: There are several types of testing. Some involve certain types of blood tests. Another method is to do a series of skin tests done by pricking the skin and applying different allergens. Other tests are provocative tests that can involve challanging the patient with allergic materials. Testing should be done by doctors specializing in allergy to obtain the best results. ...Read more
Skin & blood tests: Prick testing with allergenic extracts or fresh foods can help confirm allergy, as can blood tests for specific ige antibodies (rast-type tests). However, both types of testing can produce false positive results, and confirmation with food challenges may be needed. ...Read more
Not exactly: The ability to react to certain proteins in an allergic way is passed on from parents to their children, but a specific allergy is not. So if a mom is allergic to pollen and the dad is allergic to fire ants, their child may develop allergies but it may be to a food instead. If 1 parent has allergies, the child is 50% likely to develop allergies, but it's a 75% chance if both parents are allergic. ...Read more
"Hydroxyurea may affect fertility (ability to have children), whether a man or a woman."Please advice..
It is a chemotherapy drug (a mild one, that doesn't have severe side effects, once it has been checked, worries about it lowering blood counts too much are not much).
It does lower sperm quality and that effect can last after it is stopped.
http://www. Ncbi. Nlm. Nih. Gov/pubmed/17316339 ...Read more
Can I as a 46 year old, take children's Benadryl. It's all I have in the house and my allergies are terrible.
Okay to use: Okay to use children's Benadryl. Dosage will be 20 ml (4 teaspoons) per dose. ...Read more
Where can I find a statistic for the number of children who died from allergies causing anaphylaxis in the u.S.?
Only overall numbers: The incidence of anaphylaxis in children is unknown. Estimates of anaphylactic deaths (from drugs, foods, insect stings, and latex) in the us are 0.002 percent annually (2 per 100, 000): 500 fatalities from penicillin anaphylaxis; 40 fatalities from bee stings; 125-150 from food anaphylaxis. ...Read more
My husband has nut and fish allergies. I have 4 children, 2 without allergies should I get rest of kids tested before giving them these foods?
I give my 17mnth old 1/2 teaspoon of children's zyrtec (cetirizine) for allergies but some days it's not enough. Can I increase the dose or try something differ t?
Do not increase: A 17 month old should not have allergies to inhaled items like dust or pollen. Zyrtec (cetirizine) could cause drowsiness and I would avoid long term use of zyrtec (cetirizine) in your child. If your child has a runny or stuffy nose that is unresponsive to zyrtec (cetirizine) then see your doctor to make sure there isn't an infection brewing. ...Read more
Yes: Not all of the food allergies are created equal. Food allergies like dairy, egg, wheat tend to be outgrown. Tree nut and peanut are less likely (although recent studies suggest that 20-30% outgrow the peanut allergy). Environmental allergies tend to "grow on you" with time. Note: the allergy test may remain positive despite the child having outgrown the allergy. Consult with an allergist. ...Read more
It depends: It really depends on the age of the child, and whether you're talking about food or environmental allergies. I generally will skin test children over age 2 for environmental allergies, while many younger kids need food testing. In terms of frequency, children with environmental allergies may benefit from repeat testing after 2 years, as their allergies can change as they get older. ...Read more
Hygiene hypothesis: The immune system has two opposing arms, one makes protective antibodies against bacteria and viruses, the other makes allergic antibody. One theory is that early antibiotic use disrupts the gut flora which tips the scale away from fighting infection and more toward making allergic antibodies. Clean environments might be at fault as well, farm kids don't get allergies as much as city kids. ...Read more
Sometimes: But not all the time. Nasal allergies are not a frequent cause of a really bad persistent cough. In a child with allergies and a really bad cough (assuming no fever) I would be concerned about a reactive airway/asthma type condition. If the child also had eczema I would be even more concerned. ...Read more
Breastfeed!: Breastfeeding is shown to be protective for children with a strong family history of allergies. If unable to breast feed, try a hypoallergenic formula such as "nutramigen" or "alimentum". Try to avoid introducing baby foods until 4-6 months of age; once you do, introduce them slowly. Interestingly, exposure to dogs & cats appears to reduce the risk of becoming allergic to those household pets! ...Read more
Nasal, eye, skin: Children will exhibit sneezing, itchy nose/eye, stuffy nose or cough with close exposures with pets. If licked by a cat or dog and allergy is present, a rash could develop at that site. The allergies could manifest as asthma with cough, wheezing or difficulty breathing. Typically a pattern will be seen, but if it is an indoor pet, the symptoms may be continuous. ...Read more
No: The pain is minimal with skin testing, similar testing can be done with a blood test which requires some blood being withdrawn with a needle. ...Read more