Doctor insights on:
See below: Not sure of your question. Those are two completely different drugs used for totally different things. Aspirin is an anti-platelet drug to make your platelets less sticky so they don't form clots in the blood vessels that could lead to heart attack or stroke. Hydralazine acts on the blood pressure, pulse rate, and dilation of the blood vessels. ...Read more
Not a MOA: Hydralazine is a direct smooth muscle relaxer based on its intracellular action on Calcium. In situ, it does not appear to have a direct effect on the vagus nerve, but rather may have an effect on the sinoatrial node and a reflex response (increased heart rate) due to the decreased blood pressure (baroreceptor response). ...Read more
Hydralazine: It relaxes vascular smooth muscles, resulting in dilation of arteries & arterioles (small vessels). ...Read more
Few reasons: It's a vasodilator (dilates blood vessels) and has a couple of common uses 1: it can be used for high blood pressure, although usually not a first choice these days since its dosed frequently when given in pill form. 2: it's used in heart failure. It's called an after-load reducer. Basically makes it easier for a weakened heart (heart failure) to push blood out to the body. ...Read more
Fatigue, see below: Most side effects are rare, but of the ones that patients are more likely to experience with this med, fatigue/tiredness, diarrhea, and upset stomach are more common. It rarely, and I mean rarely, can cause symptoms similar to systemic lupus erythematosis (sle or lupus). This drug induced lupus is reversible when the med is stopped. I think Labetalol during pregnancy is a better option. ...Read moreSee 1 more doctor answer
Do you mean dosage?: The normal dosage for adults is 0.143 to 0.357 mg/kg per 6 hours orally to start, then after many weeks 0.143 to 0.357 mg/kg per 6 hours as needed. If given iv, 5-10mg per 10-15 min to a maximum of 50mg. ...Read more
Should not: These are not the same class of medications, so a substitution depends on the original indcation. Check with your prescribing physician. ...Read more
If I was prescribed Diovan (valsartan) hct, can I subsitute it with hydralazine HCl for cost purposes?
Can I substitute Norvasc (amlodipine) 10mg for hydralazine HCl 75mg and if so, at what dosage level?
Meds: This needs to be done underthe guidance of a doctor, do not self medicate. ...Read more
I have ptsd and take seroquel (quetiapine) I have nightmares is it alright to take prazosin if I take hydralazine?
Possibly: This might be a possibility, but your blood pressure will need close monitoring you'll also need to be careful about getting up from a laying down position, at least initially. Your doctors need to confer, and each know about your full list of medicines. Doses may need adjusting. ...Read more