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Doctor insights on: Hurthle Cell Lesion Thyroid

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Dr. Mark Pack
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more


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Cana follicular thyroid lesion turn malignant?

Cana follicular thyroid lesion turn malignant?

Follicular cancer: Follicular thyroid cancer the second most common cancer, after papillary. A thyroid nodule over 2.0 cm, positive/suspicious fna or symptoms are indications for thyroid lobe resection. Final pathology is often where a cancer diagnosis is made. Follicular thyroid cancer is treatable and has a good prognosis. So yes, it can turn into cancer, you need to be monitored closely. Okay to see surgeon. ...Read more

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Do papillary and follicular thyroid cancers secrete thyroglobulin?

Do papillary and follicular thyroid cancers secrete thyroglobulin?

Yes: All cells of thyroid origin secrete thyroglobulin. Measuring it to follow a cancer ONLY makes since if the whole thyroid has been removed. If you have anti thyroglobulin antibodies, that makes thyroglobulin measurements unreliable. However, rising or decreasing anti thyroglobulin antibodies can be a proxy for thyroglobulin measurements. ...Read more

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3cm hyperechoic thyroid nodule with increased vascularity, normal TSH fnac- follicular cell with hyperplastic area. What it indicates?

Uncertain: The fna can only help if it shows cancer. But in your case it is ambiguous, so your doctor should guide you what to do next?...What did he/she suggest as the next step? Most doctors would next recommend either surgical excision or monitor closely for some time and see if it is growing in size in which case it has to be taken out. ...Read more

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What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

What does benign follicular cells in mixed micro macrofollicular pattern, focal hurthle cell changes histiocytes mean? 3cm nodule on thyroid fast grow

Discuss: For a 3 CM fast growing thyroid mass, there is a higher chance of false negative with the biopsy. Not all the mass could be cancerous and the cancer spot could have been missed during fna because the mass is big at 3 cm. Most prudent step now is to follow for size changes and rebiopsy if it changes in 1 year. Depending on your age and current compressive symptoms, surgery is an option. ...Read more

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Solitary, solid nodule with intranodular flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Solitary, solid nodule with intranodular  flow and follicular neoplasm cells. Afirma came back suspicious. What's likelyhood of malignancy?

Ask your doctor: The doctor who ordered your biopsy has responsibility to explain to you the meaning of the results. If the biopsy shows neoplastic cells, that usually means Cancer cells. But you should get this clarification from your doctor. ...Read more

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Is a heterogeneous thyroid nodule cancerous?

Is a heterogeneous thyroid nodule cancerous?

Possibly: Each thyroid nodule has an approx. 5% chance of malignancy, thus a heterogenous could be cancerous. Looking at it the other way, a heterogenous nodule has a 95% chance of not being cancerous. ...Read more

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3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

Not necessarily...: The fact that FNA was reported as benign, the nodule is unlikely to be malignant. Small droplets of benign colloid often mimic "microcalcificatins" of papillary tumor, hence caution is advised. I would suggest repeating the FNA, and consider also collecting samples for gene profiling studies, such as, those manufactured by Veracyte and Asuragen (Note:I have no financial/other interest.) ...Read more

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Thyroid fnac report-atypia of undetermined significance or follicular neoplasm. What it means? Treatment?

Thyroid FNA: Hi. A follicular neoplasm of undetermined significance means the cytology doesn't meet criteria for cancer or benign, thus the "undetermined significance". Historically, most of these turn out to be benign, but a significant subset are cancer. It appears they did not do gene testing. Next step would usually be surgical excision of the nodule, frozen section analysis, then total thyroidectomy if CA ...Read more

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Is follicular thyroid carcinoma treatable?

Is follicular thyroid carcinoma treatable?

Very treatable: Surgical resection always needed but depending on size of lesion, proximity to isthmus and whether nodes seen on scan procedure of choice decided on. Under 30 years of age lesion very curable even in face of nodes. Over 50 I find surgery may be difficult because of invasion occasionally into larynx and carotid artery. If surgery effective may need p.o. RT. ...Read more

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Papillary thyroid cancer follicular variant, what to do?

Papillary thyroid cancer follicular variant, what to do?

Remove lesion: The presence of cancer of the thyroid is best handled by thyroid resection. Depending on the size and location, a lobectomy or total thyroidectomy should be performed. Lymph nodes if present are resected. Radical neck not ut9ilized for node removal. Post oo radio iodine may be indicated and use of those meds to compensate for those anatomical structures removed. ...Read more

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What should you eat when you have hyper thyroidism?

What should you eat when you have hyper thyroidism?

Hyperthyroidism: There are no food that reverse hyperthyroidism or make it worse. ...Read more

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My thyroid nodule report says rare macrophages and colloid consistent with follicular lesion of undetermined significance. Foll...lesion can't exclude?

Follow advice of end: Your Endocrinologist can guide you best. Your biopsy appears to be inadequate to make a definite diagnosis. Future follow up with an endocrinologist is advised so that your thyroid can be monitored for any further growth of this nodule which is easy to do with an ultrasound. ...Read more

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Thyroid nodule of the right lobe. Fna indicated follicular lesion-also hypothyroid, family history of malignant thyroid nodules. Options?

Surgery or...: A repeat biopsy combined with an afirma assay test may give you somewhat better guidance, but with your history and risk factors, surgery may be the best option. By the way, why are you taking generic T4 an Armour Thyroid together? There is no way to monitor the dosage properly as the lab tests will be unreliable. Brand name T4 is better, safer and more reliable. ...Read more

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Abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages and colloid present, favor adenomatoid nodule. ?

Glad to hear it: Your thyroid nodule is benign. You may have several and they are probably benign as well. Nobody knows what causes these little adenomatous nodules, but they have very little tendency to turn bad. ...Read more

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1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

1 CM solid node l thyroid lobe a mixed micro and macro- follicular lesion fna consists of follicular cells in small follicles microfollicles & small sheets displaying extensive hurthle cell changes ?

Now benign: From your information it isa benign adenoma , hurthle cell are little larger pinkish cell , but have higher incidence of malignant transformation than follicular , to hurthle cell carcinoma , unlike follicular , it will spread to lung , bone etc, follow your doctor's advice. ...Read more

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Sister had papillary & hurthle thyroid cancer. I have 9x3x8mm and 7x3x4 complex primarily hypoechoic nodules . Heterogeneous echotexture. Biopsy?

Sister had papillary & hurthle thyroid cancer. I have 9x3x8mm and 7x3x4 complex primarily hypoechoic nodules . Heterogeneous echotexture.  Biopsy?

Always: regardless if you have a family history or not thyroid mass need to be biopsied. they start with something called FNA which mean fine needle aspiration, a procedure could be done in the surgeon office. please see a specialist for that either a surgeon or an endocrinologist good luck ...Read more

Dr. Scott Bolhack
802 doctors shared insights

Wounds (Definition)

Wound = injury to tissue. May include ...Read more