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Doctor insights on: Huntington's Disease Symptoms

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Dr. Alan Ali Dr. Ali
2 doctors agreed:
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What are presenting symptoms of Huntington disease?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
What are presenting symptoms of Huntington disease?

Huntington: It is a neurodegenerative genetic disorder that affects muscle coordination & leads to cognitive deficits & psychiatric problems. Symptoms become noticeable between ages 35 & 45, & include jerky random uncontrollable movements called chorea, memory problems, mood changes, etc. ...Read more

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How old are people typically when the symptoms of huntington disease show up?

How old are people typically when the symptoms of huntington disease show up?

Middle adult age: Huntington's most commonly begins in mid adult hood, for example, between 35 and 40 years of age. ...Read more

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I have headche for months and we have huntington disease in the family is this an hd symptoms or it can be something else?

I have headche for months and we have huntington disease in the family is this an hd symptoms or it can be something else?

Can have many causes: Headache is not considered to be a common symptom of hd. Depending on the type of headaches you have, they can be migraines, tension headache, or cluster headaches. Causes are many; including viral infection, chronic sinusitis, drug/alcohol withdrawal, change of medications, to name a few. Consult your physician if it continues. ...Read more

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Can you tell me how can trinucleotide repeat mutation cause the symptoms in huntington disease?

Can you tell me how can trinucleotide repeat mutation cause the symptoms in huntington disease?

No. No one can.: We know that too many CAG repeats in the huntingtin gene causes HD, but the function of the gene is not yet known. ...Read more

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Are coughing and vomitting during eating are symptoms of huntington disease??

Are coughing and vomitting during eating are symptoms of huntington disease??

Unlikely.: Coughing and vomiting during eating is concerning for GI issues, such as swallowing disorders or esophageal motility disorders. Huntington's disease is generally characterized by involuntary movement and psychiatric problems. Mayo Clinic has an excellent article: http://www.mayoclinic.org/diseases-conditions/huntingtons-disease/basics/symptoms/con-20030685 ...Read more

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What is the mutation that causes huntington disease?

What is the mutation that causes huntington disease?

HD gene: The abnormal gene is located on chromosome 4 and codes for a protein called huntingtin. This protein has many functions in the body and the way the abnormal protein causes huntington's dis is not known, . ...Read more

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What can cause huntington disease to happen?

What can cause huntington disease to happen?

YES !!: Huntington's disease (named after the long island doctor who described it ) has dementia , chorea (a dance like involuntary movement) and family history as its main features it is transmitted by a dominant gene (50% chance of it occuring in the offspring). It is at present incurable although the movements can be modified by medication. ...Read more

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Does huntington disease mostly occur in one gender?

Does huntington disease mostly occur in one gender?

NO: As it is due to a dominant gene it can affect males and females. ...Read more

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How much does the huntington disease examination cost?

Varies: Check with your local lab. Some of these screening tests are covered by your insurance. It appears you are 28 years old and likely would have symptoms. Review your family history and see your MD/neurologist. All the best. ...Read more

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Can huntington disease be detected before the child is born?

Can huntington disease be detected before the child is born?

With PGD: I suspect that if a pregnancy is conceived by ivf, preimplantation genetic diagnosis could be used to detect which embryos carry the genetic factors to cause huntington's disease, allowing one to only implant embryos that lack that factor. At this point, it cannot be detected in a natural pregnancy, though technology for noninvasive detection of various disorders is under development. ...Read more

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What is the frequency of huntington disease in the population?

Huntingtons frequenc: The prevalence of Huntingtons disease is about 5 for every 100,000 people in the world. ...Read more

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Would huntington disease be detected before the child is born?

Yes in Mom and child: A gene test can be done on any individual. If the mother carries the gene, she will eventually become symptomatic with huntington disease. Any child of hers will have a 50% chance of inheriting the gene and the disease. Prenatal testing of the child in utero can be performed. Any sort of prenatal testing should involve a genetic counselor consultation, as there are many issues to consider. ...Read more

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Can you tell me, are there carrier forms and or lethal forms of huntington disease?

Dominant gene: By definition you cannot havea carrier form of Huntington's disease 50% of children will be affected although the condition may not cause symptoms until middle age. The disease is a combination of FAMILY HISTORY, DEMENTIA and INVOLUNTARY MOVEMENTS ...Read more

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Where in the genome is huntington disease?

Huntington: The answer can be found here: http://www.Genome.Gov/10001215. ...Read more

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Does huntington disease cause migrane?

Does huntington disease cause migrane?

Not typically.: However, if you read about symptoms associated with Huntington's disease, the list is incredibly long. It seems that Huntington's disease gets blamed for everything. Headache is on that list, but not specifically migraine. ...Read more

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Is pku and huntington disease the same disease entity?

Some comments: Pku is a problem with children and this needs early diagnosis to prevent profound complications. Huntington's chorea is an autosomal dominant disorder occurring later in life, and is relatively rare, but genetic counseling might be valuable. Neither disorder has any relationship to the other. ...Read more

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Does huntington disease cause headache?

Does huntington disease cause headache?

Tension Headaches: Indirectly yes. Spasms in the neck from Huntington's disease can cause headaches from tense muscles that insert on the skull. These tension headaches are managed with massage, physical therapy, muscle relaxers and Botox injections. ...Read more

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Does huntington disease cause headache?

Does huntington disease cause headache?

Not primarily: Headache is not a core component of huntington's chorea, but no reason why a co-morbidy of migraine, or side effects of medication could not cause headache. ...Read more

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Is there any chance to find a cure for huntington disease in the coming years?

Not that I am aware: Of at this time. Unfortunately, this is a genetic condition. I'd highly consider genetic counseling before family planning. ...Read more