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Doctor insights on: Huntington S Disease Dominant Or Recessive

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Dr. Alan Ali Dr. Ali
2 doctors agreed:
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What are presenting symptoms of Huntington disease?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
What are presenting symptoms of Huntington disease?

Huntington: It is a neurodegenerative genetic disorder that affects muscle coordination & leads to cognitive deficits & psychiatric problems. Symptoms become noticeable between ages 35 & 45, & include jerky random uncontrollable movements called chorea, memory problems, mood changes, etc. ...Read more

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What is the mutation that causes huntington disease?

What is the mutation that causes huntington disease?

HD gene: The abnormal gene is located on chromosome 4 and codes for a protein called huntingtin. This protein has many functions in the body and the way the abnormal protein causes huntington's dis is not known, . ...Read more

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What can cause huntington disease to happen?

What can cause huntington disease to happen?

YES !!: Huntington's disease (named after the long island doctor who described it ) has dementia , chorea (a dance like involuntary movement) and family history as its main features it is transmitted by a dominant gene (50% chance of it occuring in the offspring). It is at present incurable although the movements can be modified by medication. ...Read more

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What is the frequency of huntington disease in the population?

What is the frequency of huntington disease in the population?

Huntingtons frequenc: The prevalence of Huntingtons disease is about 5 for every 100,000 people in the world. ...Read more

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Where in the genome is huntington disease?

Where in the genome is huntington disease?

Huntington: The answer can be found here: http://www.Genome.Gov/10001215. ...Read more

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Does huntington disease cause migrane?

Does huntington disease cause migrane?

Not typically.: However, if you read about symptoms associated with Huntington's disease, the list is incredibly long. It seems that Huntington's disease gets blamed for everything. Headache is on that list, but not specifically migraine. ...Read more

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Is pku and huntington disease the same disease entity?

Some comments: Pku is a problem with children and this needs early diagnosis to prevent profound complications. Huntington's chorea is an autosomal dominant disorder occurring later in life, and is relatively rare, but genetic counseling might be valuable. Neither disorder has any relationship to the other. ...Read more

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Does huntington disease mostly occur in one gender?

Does huntington disease mostly occur in one gender?

NO: As it is due to a dominant gene it can affect males and females. ...Read more

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How much does the huntington disease examination cost?

Varies: Check with your local lab. Some of these screening tests are covered by your insurance. It appears you are 28 years old and likely would have symptoms. Review your family history and see your MD/neurologist. All the best. ...Read more

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Can huntington disease be detected before the child is born?

Can huntington disease be detected before the child is born?

With PGD: I suspect that if a pregnancy is conceived by ivf, preimplantation genetic diagnosis could be used to detect which embryos carry the genetic factors to cause huntington's disease, allowing one to only implant embryos that lack that factor. At this point, it cannot be detected in a natural pregnancy, though technology for noninvasive detection of various disorders is under development. ...Read more

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Would huntington disease be detected before the child is born?

Yes in Mom and child: A gene test can be done on any individual. If the mother carries the gene, she will eventually become symptomatic with huntington disease. Any child of hers will have a 50% chance of inheriting the gene and the disease. Prenatal testing of the child in utero can be performed. Any sort of prenatal testing should involve a genetic counselor consultation, as there are many issues to consider. ...Read more

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How old are people typically when the symptoms of huntington disease show up?

Middle adult age: Huntington's most commonly begins in mid adult hood, for example, between 35 and 40 years of age. ...Read more

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Can you tell me, are there carrier forms and or lethal forms of huntington disease?

Dominant gene: By definition you cannot havea carrier form of Huntington's disease 50% of children will be affected although the condition may not cause symptoms until middle age. The disease is a combination of FAMILY HISTORY, DEMENTIA and INVOLUNTARY MOVEMENTS ...Read more

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I have headche for months and we have huntington disease in the family is this an hd symptoms or it can be something else?

Can have many causes: Headache is not considered to be a common symptom of hd. Depending on the type of headaches you have, they can be migraines, tension headache, or cluster headaches. Causes are many; including viral infection, chronic sinusitis, drug/alcohol withdrawal, change of medications, to name a few. Consult your physician if it continues. ...Read more

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Does huntington disease cause headache?

Does huntington disease cause headache?

Tension Headaches: Indirectly yes. Spasms in the neck from Huntington's disease can cause headaches from tense muscles that insert on the skull. These tension headaches are managed with massage, physical therapy, muscle relaxers and Botox injections. ...Read more

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Does huntington disease cause headache?

Does huntington disease cause headache?

Not primarily: Headache is not a core component of huntington's chorea, but no reason why a co-morbidy of migraine, or side effects of medication could not cause headache. ...Read more

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Can huntington disease be genetic, but triggered by other factors?

Always genetic: Hd is a genetic disease. Anyone that carries the gene will get the disease, but knowing that you have the gene does not tell you your age of onset at the disease. The onset of the disease will occur regardless of other factors if one lives long enough. ...Read more

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Are coughing and vomitting during eating are symptoms of huntington disease??

Are coughing and vomitting during eating are symptoms of huntington disease??

Unlikely.: Coughing and vomiting during eating is concerning for GI issues, such as swallowing disorders or esophageal motility disorders. Huntington's disease is generally characterized by involuntary movement and psychiatric problems. Mayo Clinic has an excellent article: http://www.mayoclinic.org/diseases-conditions/huntingtons-disease/basics/symptoms/con-20030685 ...Read more

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Is there any chance to find a cure for huntington disease in the coming years?

Not that I am aware: Of at this time. Unfortunately, this is a genetic condition. I'd highly consider genetic counseling before family planning. ...Read more

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Can you tell me how can trinucleotide repeat mutation cause the symptoms in huntington disease?

Can you tell me how can trinucleotide repeat mutation cause the symptoms in huntington disease?

No. No one can.: We know that too many CAG repeats in the huntingtin gene causes HD, but the function of the gene is not yet known. ...Read more

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My girlfriends mom has huntington disease... If my gf and I have kids what is the chance they will have the disease too?

My girlfriends mom has huntington disease... If my gf and I have kids what is the chance they will have the disease too?

Genetic consult: It's great that you think ahead. Today there are genetic markers for huntington that can be studied & if your gf is positive she will both get huntington disease & potentially pass it to her kids (risk = 50% per conception). A consultation with a medical geneticist should be able to clear the air on this issue and analyse any risks from either side of the family. ...Read more

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Why pain killers don't.reduce the headache pain caused by huntington disease?

Why pain killers don't.reduce the headache pain caused by huntington disease?

Headache: In people with Huntington's disease may need to be treated differently than headaches in others. If one suffers from dystonia anti-spasmodic medication should be tried. Otherwise headache and Huntington's disease is treated like a headache and people without Huntington's disease ...Read more

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Help docs, is huntington disease a side effect of seizure meds?

Help docs, is huntington disease a side effect of seizure meds?

Unfortunately not: I say, "unfortunately" only because then, we might have a controllable risk factor to deal with in order to help curb or eliminate the disease. However, it comes about as the result of a genetic derangement and we're still in the dark as to what that's exactly all about. ...Read more

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My boyfriend has huntington disease. His mood are very up and down could he be prescribed bi polar meds to help cause the anti depressant are not work?

My boyfriend has huntington disease. His mood are very up and down could he be prescribed bi polar meds to help cause the anti depressant are not work?

Maybe: If being "up" were consistent with an episode of mania, then consideration should be given to prescribing "bipolar meds" if being "up" is just no longer being depressed then they would not be appropriate. ...Read more

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Huntington's disease, an often fatal disease of the central nervous system, is inherited from a dominant alle, is this right?

Huntington's disease, an often fatal disease of the central nervous system, is inherited from a dominant alle, is this right?

Yes: Autosomal dominant disorder with the presence of excess numbers of tri-nucleotide repeats within the Huntington's gene on human chromosome 4. ...Read more

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What is the frequency of huntington's disease in our u.S. Population?

4.1-8.4 per 100,000: See following reference under epidemiology http://emedicine.Medscape.Com/article/1150165-overview#a0199.

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What is huntington's disease?

What is huntington's disease?

Movement disorder: Hd is the result of an inherited abnormality due to genetic errors resulting in abnormal movements and behavioral problems. Hd can be diagnosed with genetic tests. It is usually apparent clinically in the 4th or 5th decades. ...Read more

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How rare is huntington's disease?

Huntington: The answer can be found here: http://www.Genome.Gov/10001215. ...Read more

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How common is huntington's disease?

5-10/100,000: Huntington's disease is a progressive neurodegenerative disease that is autosomal dominant. Most estimate that it occurs in 5-10 per 100, 000 population. There does not appear to be any sexual discrimination. It is a progressive disease that usually becomes manifest in patients 30-40 years old. ...Read more

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How does huntington's disease progress?

How does huntington's disease progress?

Slowly: Most patients start out with muscle twitching, depression, anxiety and progress over time to uncontrolled muscle movements, difficulty speaking and swallowing, and loss of control of bladder and bowels. ...Read more

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What does huntington's disease look like?

Abnormal involuntary: choreiform movements. If you want to see what chorea looks like, a web search for video clips should turn some up. Also check out hdsa.org for more information. ...Read more

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How does a person get huntington's disease?

How does a person get huntington's disease?

Genetic disorder: Huntington's disease named after a long island physician is caused by a dominant gene in either parent it is accompanied by dementia and involuntary movement (chorea). ...Read more

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What are the tests for huntington's disease?

What are the tests for huntington's disease?

Genetic Test: There is a very well-known, definitive test that can be done. It's a genetic test (avaiable from athena laboratories, which detects the presence or absence of the tri-nucleotide expansion pathology on chromosome 4. Because this an autosomal dominant gene, on average, 50% of descendants will alsoanifest the disease because they received the gene from the affected parent. ...Read more

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What are the stages of huntington's disease?

YES !!: Huntington's disease (named after the long island doctor who described it ) has dementia , chorea (a dance like involuntary movement) and family history as its main features it is transmitted by a dominant gene (50% chance of it occuring in the offspring). It is at present incurable although the movements can be modified by medication. ...Read more

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What are early signs of huntingtons disease?

What are early signs of huntingtons disease?

Many signs: 50% of Huntington's patient develop psychiatric symptoms and 50% develop neurological symptoms which are usually involuntary movements - including chorea,a the tho sis, dystopia and tics. ...Read more

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Symptoms of huntingtons disease, is it fatal?

Symptoms of huntingtons disease, is it fatal?

No cure but treatmen: It is a relentless, progressive degenerative neurological disease. There is no cure for the disease. The symptoms include chorea (dance-like movements) for which there is an fda approved medicine and psychiatric symptoms usually with disinhibition. Any child of a patient has a 50% chance of inheriting the disease. One should see a movement disorders neurologist for treatment. ...Read more

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Please help me? What is huntington's disease?

Huntington's Disease: is a neuro-degenerative disorder. Each child of a person with HD has a 50% chance of inheriting it. Symptoms are involuntary movements called chorea, cognitive impairments & psychiatric disorders.There are medications to help control the movement & emotional aspects of the disease. Unfortunately, they do not alter the course of the disease. See http://www.hdsa.org/about/our-mission/what-is-hd.html ...Read more

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What are the symptoms of huntington's disease?

What are the symptoms of huntington's disease?

Movement disorders: Changes in movement with a lack of coordination. You are usually unsteady while walking. As the disease progresses, the jerky, or spastic movements increase, with a decline in mental status and development of psychiatric disorders in the last stages of the disease. ...Read more

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