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Doctor insights on: Humira Psoriasis

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Methotrexate vs humira (adalimumab), rheumatoid arthritis?

Methotrexate vs humira (adalimumab), rheumatoid arthritis?

Methotrexate: is a first line drug for rheumatoid arthritis, used frequently with hydroxchoroquine and sulfasalazine. Humira is an expensive biologic for those who have failed traditional first line regimens!

Humira works well for RA, but it is second line! ...Read more

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Dr. Thomas Namey
1,035 doctors shared insights

Psoriasis (Definition)

An autoimmune disease that causes itchy, thickened, skin lesions on the skin, nail changes, and occasionally joint arthritis. ...Read more


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Methatrexate for psoriasis?

Methatrexate for psoriasis?

Can be excellent: Can be an excellent drug, if the severity of the psoriasis requires it and with close monitoring for side effects. ...Read more

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Methotrexate vs humira (adalimumab), rheumatoid arthritis question?

Methotrexate vs humira (adalimumab), rheumatoid arthritis question?

MTX vs Humira (adalimumab): These drugs fight RA in completely different fashions. Mtx is the consensus first round choice of drugs to treat ra, both by the acr and eular (european version). Most, if not all, insurances require treatment failure with mtx before you start humira, (adalimumab) a much more expensive drug. In most cases, even if Humira (adalimumab) is started, patients will remain on mtx. ...Read more

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What's more effective for pustular psoriasis, methotrexate or enbrel (etanercept)?

Both: Both can be effective, personally i feel Enbrel (etanercept) is safer. There are other options. Talk it over with your dermatologist. ...Read more

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Anyone taking humira (adalimumab) for rheumatoid arthritis?

Anyone taking humira (adalimumab) for rheumatoid arthritis?

Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it binds to tnf-a rendering ineffecftive. It is completely human in origin. A good choice for those who do prefer home sc injection, every two weeks. It is my favorite tnf-a class drug. ...Read more

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Is methotrexate or humira (adalimumab) better for rheumatoid arthritis?

Is methotrexate or  humira (adalimumab) better for rheumatoid arthritis?

It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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Anyone tried enbrel (etanercept) for treating rheumatoid arthritis?

Anyone tried enbrel (etanercept) for treating rheumatoid arthritis?

Many patients: Rheumatoid arthritis can often be controlled with some of the newer medications including enbrel (etanercept). Many patients are saved from irreversible crippling of the joints. The key is to get early diagnosis and effective treatment to prevent worsening. Enbrel (etanercept) is a biologic response modifier meaning that the drug is made by a biological system. The drug can be very effective. Untreated RA has huge risks. ...Read more

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Can methotrexate treat psoriasis?

Can methotrexate treat psoriasis?

Yes. Agree, but....: Methotrexate can be very effective. However, the first studies raising the specter of liver disease came from psoriasis patients on daily low dose oral mtx!. The first pass effect is dangerous for the liver. Mtx cannot be adjudicated aqs an oral drug. Absorption is variable (40-90%), causes GI upset, and hits the liver first. I only use subcutaneous mtx once weekly. This is the safest! ...Read more

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Is arava (leflunomide) effective for rheumatoid arthritis?

Is arava (leflunomide) effective for rheumatoid arthritis?

It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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Is humira (adalimumab) an effective treatment for psoriasis?

Is humira (adalimumab) an effective treatment for psoriasis?

Yes: Humira (adalimumab) is one of our tnf inhibitors and it is a potent medication. It can quite helpful for psoriasis. You and your physician need to discuss the risks and benefits of the drug versus how bad your psoriasis is. ...Read more

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Psoriasis+psor. Arthritis..Methotrexate 15mg for 2 mos. Already+humira weekly..Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe..Ok?

Nod to others:: Humira is a tnfa antibody, and is similar to envbrel. Remicade (infliximab) is an antibody to the tnfa receptor, so it works differently. But i would have tried you on leflunomide, and oral drug, before starting biologics. ...Read more

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Treat psoriasis with cyclosporine?

Treat psoriasis with cyclosporine?

Last resort: Cyclosporine is an effective treatment for psoriasis - but it is usually used only when all else has failed, because it is toxic to the liver and kidneys, among other things, and weakens the immune system. It should never be taken without close monitoring by an expert in its use for that purpose (usually a dermatologist). ...Read more

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Humira (adalimumab) every 2 weeks stopped working&got a bad psoriasis flare-up...Now on humira (adalimumab) weekly w/15mg methotrexate but still have bad psoriasis.U recommend?

Psoriasis: While Humira is an excellent therapy for severe psoriasis, there are times when it stops working. Another option for you may be stelara (ustekinumab) which is also an injectable treatment which works a little differently than does Humira and is extremely effective in many patients. ...Read more

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How is enbrel (etanercept) used for treating rheumatoid arthritis?

How is enbrel (etanercept) used for treating rheumatoid arthritis?

Second line.: While Enbrel (etanercept) can be used alone, it works better in tandem with methotrexate. It is given by subcutaneous injection once per week, the dose being dependent on body size. It is also indicated for psoriatic arthritis and spondylitis. Most insurers want the patient to have been on lesser drugs. These would include incomplete response to mtx, sfz, and ho-q. It binds to tnf-alpha, which caues inflamm. ...Read more

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How to cure psoriasis?

How to cure psoriasis?

Psoriasis: There is no cure for psoriasis only control. There are prescription topical steroids. There are intralesional steroid injections. The biologics like Humira, Enbrel, Remicade, (infliximab) and Otezla are very effective at treating psoriatic arthritis and also the skin lesions of psoriasis. Patients with psoriasis are also prone to cardiovascular disease but the biologics help reduce this. ...Read more

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Was on humira (adalimumab) weekly&psoriasis came back. Now on enbrel&25mg methotraxte.Do u think psorias will clear?Y did humira (adalimumab) stop working?Stress overpower it?

Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this. ...Read more

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I quit Humira (adalimumab) for my Psoriasis/psoriatic arthritis for 4 1/2 months. Symptoms returning. Can I restart my normal dose or is a loading dose needed?

Clinical judgement: On whether you will need the medicine again in the first place, as why did you quit using it? Decision to restart is based on clinical judgement of the physician(s) managing your case. As for the loading dose, it may be needed if the decision is to restart, best wishes ...Read more

Dr. John Chiu Dr. Chiu
2 doctors agreed:
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How well does humira (adalimumab) actually work for psoriasis? And what does it mean to be moderate/severe?

Dr. John Chiu Dr. Chiu
2 doctors agreed:

Well enough: Humira (adalimumab) targets the tumor necrosis factor (tnf) which is involved in inflammation and immune response. However when there is too much, the target may get damaged. Psoriasis involving mainly the skin, phototherapy may be helpful. But for arthritis, Humira (adalimumab) (and other tnf inhibitors) is a good option. They all have similar side effects- the risk of severe infection. Good luck to you. ...Read more

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Is humira (adalimumab) an effective treatment for psoriasis?

Yes: Humira (adalimumab) is one of our tnf inhibitors and it is a potent medication. It can quite helpful for psoriasis. You and your physician need to discuss the risks and benefits of the drug versus how bad your psoriasis is. ...Read more

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I Started taking humira (adalimumab) in January 2014, 40mg bi weekly, I have Psoriasis Arthritis. It was great. I have a problem with the insurance and I quit Hum?

I Started taking humira (adalimumab)  in January 2014, 40mg bi weekly, I have Psoriasis Arthritis. It was great. I have a problem with the insurance and I quit Hum?

What's the ?: There are alternatives for Humira (adalimumab) for your condition but the first thing would be for your doctor to request authorization which may require a peer-to-peer discussion. If still unsuccessful, consider writing to your state's insurance commissioner to file a complaint. ...Read more

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Humira (adalimumab) every 2 weeks stopped working&got a bad psoriasis flare-up...Now on humira (adalimumab) weekly w/15mg methotrexate but still have bad psoriasis.U recommend?

Psoriasis: While Humira is an excellent therapy for severe psoriasis, there are times when it stops working. Another option for you may be stelara (ustekinumab) which is also an injectable treatment which works a little differently than does Humira and is extremely effective in many patients. ...Read more

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Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! both should be tried only after Methotrexate therapy has failed! ...Read more

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I was on humira (adalimumab) biweekly for psoriais and psoriatic arthritis. Now i'm on weekly because psoriasis came back. Is weekly good idea & what r side effect?

I was on humira (adalimumab) biweekly for psoriais and psoriatic arthritis. Now i'm on weekly because psoriasis came back. Is weekly good idea & what r side effect?

Some people!: Some people who are larger, or have more severe inflammation may need more, and a weekly dose is not rare in these instances. Twice weekly, sounds like too much! dr. Litt said this; perhaps you used the wrong term!? ...Read more

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Im taking HUMIR(Adalimumab) beacuseof Psoriasis. I used to take clonazepam sometimes to sleep because of Imsomnia. Im wondering If i still can take clonazepam while humira. Is there a problem, Is contraindicated?

Im taking HUMIR(Adalimumab) beacuseof Psoriasis. I used to take clonazepam sometimes to sleep because of Imsomnia. Im wondering If i still can take clonazepam while humira. Is there a problem, Is contraindicated?

OK: OK to take with Humira. Note that this is best used as an occasional aid to sleep. If you have a chronic problem you should consult your Dr. For long term sleep therapy the best treatment is cognitive behavior therapy. ...Read more

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Psoriasis+psor. Arthritis..Methotrexate 15mg for 2 mos. Already+humira weekly..Dr say stelera no good for arthr...Says remicade (infliximab) or enbrel maybe..Ok?

Nod to others:: Humira is a tnfa antibody, and is similar to envbrel. Remicade (infliximab) is an antibody to the tnfa receptor, so it works differently. But i would have tried you on leflunomide, and oral drug, before starting biologics. ...Read more

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Humira and Methotrexate are not working for my psoriasis. I asked the doctor about Stelara (ustekinumab).  Dr. hasn't seen good results w/other patients on Stelera so doesn't use it. What would you recommend?

STELERA/HUMIRA/METHT: Well if you have no improvement with Humira (adalimumab) and methtrexate, than there is no harm in trying stelera.Discuss with your doctor that it is not working, so what is the harm in trying if stelera will work for you otherwise you can get a second opinion from another dermatologist. ...Read more

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Dr. Robert Lowe
181 doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more


Dr. Robert Lowe
196 doctors shared insights

Humira (Definition)

Humira is an arthritis therapy which is a ...Read more