Doctor insights on:
How Will Leukemia Affect My Everyday Life
Ongoing treatment: Most acute leukemias are treated with IV chemotherapy. Some chronic leukemias are treated with oral medication (CML) or sometimes observation alone (cll). If you are receiving IV chemo, you may lose your hair, feel tired, and be at risk for infections due to low blood counts. You will need to change your diet and activities to decrease risk of infection. Ask your doctor. ...Read more
A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more
Several ways: Fatigue is the most common symptom. Patients also have increased risk of bruising/bleeding. Infections are a higher risk for these patients as well. ...Read more
Usually many yrs: Many pts survive many years with this diagnosis./ your doctor likely discussed the genetic tests and blood work that can help define the rate of progression expected with current therapy. A small percentage have a rapid course of disease. ...Read more
Usually long: Lgl is usually indolent and may nto require any intervwention for long time, you need to follow up regualrly with your hematologist. ...Read more
Very good: Most people diagnosed with CML today are treated with imatinib or a similar drug like nilotinib or desitanib. These medications will often put people into remission. If you obtain a cytogenetic/molecular and hematologic remission people often live for years. The biggest risk is transformation to an aggressive leukemia, though this does not frequently occur. Many factors determine prognosis. ...Read more
CML has good treatme: The life expectancy for patients with CML has increased a lot during the last 10 years. Most people live upto and beyond 15-20 years and the good news is the treatment keeps geting better every year. So it is potentially going to be successfully treated. But it does require life long treatment which is a bummer! ...Read more
What is the life expectancy of a person with chronic lgl leukemia that is under control but not in remission?
Years: This is a rare entity with a good prognosis. It responds to treatment, but is not completely eliminated. ...Read more
Too many: Factors to make a specific comment. Without treatment survival is weeks to a few months. Many AML patients can be cured. ...Read more
Could you give me the median survival for the elderly, over 65, with acute lymphoblastic leukemia? Also, what was it 30 yrs. Ago? I lost a loved one in 1982, wondering if life expectancy improving in this age group? I'm not sure what the life expectancy w
Not too good...: Age older than 60 years is one of the adverse prognostic indicators for adult acute lymphoblastic leukemia. The presence of the philadelphia chromosome, mll gene rearrangement, WBC over 100, 000/microliter, and failure to achieve remission after 4 weeks of therapy are other poor prognostic factors. Overall, only 20-40% of adults are cured and these are usually the ones without adverse factors. ...Read more
Complex question: Your oncologist would have addressed this question by now. If not ask them for any precautions. It depnds on the type of leukemia that you have and also if it is in remission or not. There is often an increased risk of infections till your leukemia is in remission following treatment. ...Read more
Cures in Leukemias: CLL is usually managed by watchful waiting. CML can be held back with lifelong tyrosine kinase inhibitors, but the leukemia recurs in most pts if drug stopped. Children with ALL can be cured, but adult ALL is difficult to cure. A minority of AML can be cured with chemo (APL, CBF AML). Allogeneic transplant can be curative, but is risky. Cure depends on the individual's leukemia genetics, etc. ...Read more
Cell are abnormal: Leukemia is a cancer of blood and bone marrow. These cells are not normal and are not found in normal blood and marrow. Usually there is some type of dna damage in these cells that causes the cancer. Eventually leukemia will destroy the bone marrow, making it impossible to make normal blood cells. That is the key feature, it's progressive, destructive and eventually fatal if not treated. ...Read more
Are there other need as effective for treating lgl leukemia as methotrexate that aren't as hard on kidneys.
Obesrvation or Tx: Large granular lymphocyte (lgl) leukemia (t-cell or nk-cell) may be observed until there are symptoms due to -- anemia (low hgb), neutropenia (low wbc, anc), thrombocytopenia (low platelets). Treatment may be with methotrexate, cyclosporine, cyclophosphamide, steroids. These drugs all may have associated side effects and should be monitored. ...Read more
Anyone...: Can get leukemia. Rarely some individuals might inherit a familial disposition, and a few occupational exposures may increase risk (radiation or benzene exposure). More often it occurs from a series of random mutations that happens by bad luck in a single bone marrow stem cell. These mutations causes it to increase in number dramatically, pushing out healthy cells, but leaves them under developed. ...Read more
Leukemia cause: We don't know for sure. Leukemia develops as the consequence of a series of genetic changes in blood cell offsprings. These changes alter normal growth and differentiation of the cells, resulting in an accumulation of abnormal, immature blood cells in the bone marrow and peripheral blood. Exposure to chemicals, radiation, tobacco, or chemotherapy, infection, etc have been associated with leukemia. ...Read more
No necessarily: Long time ago that was true. But the modern treatments for leukemias are quite effective and are often curative. But the treatment is best done at a cancer center where you can find experienced leukemia specialists especially if it is an acute leukemia (as opposed to chronic leukemias which are less serious and easier to treat). ...Read more
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