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Doctor insights on: How Typical Are False Positives On Cystic Fibrosis Tests

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How typical are false positives on cystic fibrosis tests?

How typical are false positives on cystic fibrosis tests?

Not Typical: Certain rare conditions can also lead to high sweat chloride levels (the gold standard test for cystic fibrosis). However, these rare conditions (there's a list) will cause the patient to exhibit different symptoms than those consistent with cystic fibrosis, so the sweat chloride test is considered to be reliable in diagnosing CF in conjunction with the patient's history and physical exam. ...Read more

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Dr. William Walsh
981 doctors shared insights

Cystic Fibrosis (Definition)

Cystic fibrosis is a genetic disorder of the lungs and digestive tract. It causes recurrent lung infections and inhibits growth in patients. Average life expectancy of patients with cystic fibrosis ...Read more


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How frequent are false positives on cystic fibrosis tests?

As high as 15%: The sweat chloride test is still the gold standard diagnostic test for cystic fibrosis. The accuracy of this test is highly dependent on the method used and the lab it is performed in. I only trust a result that is performed in a center that is certified by the cystic fibrosis foundation. Some reasons for false positives include: lab error, malnutrition, & eczema. ...Read more

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My son had a positive sweat test for cystic fibrosis. What next?

My son had a positive sweat test for cystic fibrosis. What next?

CFF.org: In addition to the answers provided, checking with your local children's hospital and the cff.Org for more information about your care is suggested. ...Read more

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Can an early cystic fibrosis test rule out the possibility of a late in life diagnosis?

Can an early cystic fibrosis test rule out the possibility of a late in life diagnosis?

Depends on test: Depending on the original test that was performed, it is unlikely that a diagnosis of CF will be made later in life. Most of the testing that is done today is highly accurate. If you are referring to yourself, at age 31, if the diagnosis of CF has not yet been made, and you have been relatively healthy all of your life, i would say it is unlikely you have it. ...Read more

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Can you tell me what heterozygous 57 have to do with the chances of being cystic fibrosis positive?

Can you tell me what heterozygous 57 have to do with the chances of being cystic fibrosis positive?

Cystic fibrosis: This is a start. http://www.cff.org/AboutCF/Testing/Genetics/GeneticCarrierTest/ also your ObGyn and/or a genetics specialist can help explain. ...Read more

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What is a test for cystic fibrosis?

Genetic or sweat : Most cases these days are caught at birth by genetic screening tests; rarer forms can be detected by the sweat chloride test. A positive test is usually still confirmed by genetic testing. ...Read more

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How do you test for cystic fibrosis?

Sweat test: Special test of an imbalance of chloride movement in the membranes. ...Read more

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Cystic fibrosis sweat test -- who gives it?

Cystic fibrosis sweat test -- who gives it?

DNA vs. sweat tests: For sweat tests, do not trust a laboratory which is not accredited by the Cystic Fibrosis Foundation. "Sweat tests should be done at a Cystic Fibrosis Foundation-accredited care center". See http://www.cff.org/AboutCF/Testing/ ...Read more

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