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Doctor insights on: How To Wean Off Effexor

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How can I wean myself off Effexor (venlafaxine) 75mg. Safely

How can I wean myself off Effexor (venlafaxine) 75mg. Safely

With medical help: Hopefully the doctor who prescribed it will assist in terminating it. It needs to be either a very slow tapering off or being switched to a different ssri with a longer half-life and have that drug tapered. Those take a shorter time to taper. The "discontinuation" syndrome can be very troubling and serious. You want to avoid it and you can, but not alone. Best wishes for success. ...Read more

Dr. Krishna Kumar
547 Doctors shared insights

Venlafaxine (Definition)

It belong to classification of snri antidepressant also help anxiety start slow go slow its approved for depression and anxiety disorder there are some common side effects important never stop suddenly always taper slowly if you ever ...Read more


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Used Effexor (venlafaxine) 75mg, for 2 years. Weaned off at 33.5mg. Stoped taking for 4 months because I thought I was better. Having anxiety again, tried but made wors?

Used Effexor (venlafaxine) 75mg, for 2 years. Weaned off at 33.5mg. Stoped taking for 4 months because I thought I was better. Having anxiety again, tried but made wors?

Return of symptoms: Return of symptoms is not uncommon with anxiety. Are you still working with a therapist (you list "behavior therapy" your clinical findings)? If you stopped that therapy also, you could resume it and hopefully get your symptoms into remission again. Are you still on klonopin (clonazepam)? Tolerance can develop with it, and this may be happening with you also. Talk with your doctor about medication options. ...Read more

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Weaning off effexor (venlafaxine) for the past year, now at point of 37.5mg everyother day, but feeling very emotional. Is this normal?

Weaning off effexor (venlafaxine) for the past year, now at point of 37.5mg everyother day, but feeling very emotional. Is this normal?

Effexor (venlafaxine) tapering: You may be having symptoms of underlying depression/ anxiety from lower Effexor (venlafaxine) dose or you're having withdrawal symptoms. If going back up a little on the dose helps, you may need to either stay on that dose for maintenance or go more slowly with tapering Effexor (venlafaxine). Best to review with prescribing doctor and ask what to do. I hope this helps. ...Read more

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I've been on Effexor (venlafaxine) for almost ten yrs. Seems like its not helping anymore? Should I wean off nd go on something else like a ssri?

I've been on Effexor (venlafaxine) for almost ten yrs. Seems like its not helping anymore? Should I wean off nd go on something else like a ssri?

DO NOT DO ANYTHING: Without talking wtih your doctor first! You may need a change, or an augmentation strategy, but you need to be working with your doctor! ...Read more

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I'm weaning off EFFEXOR, (venlafaxine) can euphoria/excitation/feeling of being high be a withdrawal symptom?

I'm weaning off EFFEXOR, (venlafaxine) can euphoria/excitation/feeling of being high be a withdrawal symptom?

Talk to your doctor: The usual withdrawal symptoms are more flu like. The symptoms you are describing sounds more like mania. Tell your doctor about your symptoms. ...Read more

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I'm weaning off Paxil from 20mgs down to 10mgs while starting effexor (venlafaxine) at the same time 37.5mgs a day having withdrawals how long does this last?

Medication effects: Using Paxil with Effexor (venlafaxine) can increase the risk of Serotonin Syndrome- confusion, extreme changes in blood pressure, increased heart rate, fever, sweating, shaking, blurred vision, stomach cramp, nausea, vomiting, and diarrhea.
See Psychiatrist immediately for
• Diagnosis
• Medication effects, interactions
Withdrawal symptoms
• Treatment
• Frequent follow up
• Therapy for stresses in your life ...Read more

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I am under a doctor's care and currently weaning off of 15 years of using Effexor (venlafaxine) 150 mg daily. Why is it such an ordeal with this drug? Horrible.

Yes.: Getting off antidepressant is not a pleasant experience and may take a lot longer than you think. The secret is to gradually wean by small increments and if symptoms occur, go back to the last dose that you felt good at then wait a few days and decrease by12.5 mg at a time for a week then decrease again in a week. Increase your exercise level and continue following your doctor's advise. ...Read more

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As I gradually weaned off Effexor (venlafaxine) XR and took Prozac to decreased Effexor (venlafaxine) xr, my sleep hasn't been the same and I get aggravated, what is this?

As I gradually weaned off Effexor (venlafaxine) XR and took Prozac to decreased Effexor (venlafaxine) xr, my sleep hasn't been the same and I get aggravated, what is this?

More data needed: Effexor (venlafaxine) xr works on more neurotransmitters than prozac. Also depending upon the dose of the Effexor (venlafaxine) xr perhaps it was tapered too fast and or the dose of Prozac was not high enough. In either event you need to discuss it with you doc. Often their are other temporary medications that can be taken prn
to get you through the switch over phase. Also the time of day that you take the meds
is important. ...Read more

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I was taking Effexor (venlafaxine) for approximately 1 year. With the help of my doctor I managed to wean off. How long will I experience withdrawl symptoms?

I was taking Effexor (venlafaxine) for approximately 1 year. With the help of my doctor I managed to wean off. How long will I experience withdrawl symptoms?

About 3-4 weeks: Although Effexor (venlafaxine) has a relatively short half-life and is out of your system already, your body has gotten used to its presence and certain receptor sites changed as a result. I find that it takes about 3-4 weeks for the discontinuation symptoms to subside, and I often recommend that my patients take an occasional small dose of the medication if the discontinuation symptoms become unbearable. ...Read more

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I have been on Effexor (venlafaxine) XR 75mg for 10 yrs but want to wean off of it. How should I do this and what withdraw symptoms could I have? What are brain zaps?

I have been on Effexor (venlafaxine) XR 75mg for 10 yrs but want to wean off of it. How should I do this and what withdraw symptoms could I have? What are brain zaps?

Effexor (venlafaxine) withdrawal: If you've been on Effexor (venlafaxine) for that long, you need to work with your physician on a tapering schedule. First make sure that the symptoms you were having before effexor, (venlafaxine) are stable. Common discontinuation symptoms include dizziness, electric shock-like sensations, sweating, nausea, insomnia, tremor, confusion, nightmares, and vertigo. "brain zaps" are electric shock-like sensations in the head. ...Read more

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Can I wean off of Effexor (venlafaxine) XR 35mg, and take Zoloft 25mg at the same time, so there is no lapse in treatment? And how long until Zoloft starts working?

Can I wean off of Effexor (venlafaxine) XR 35mg, and take Zoloft 25mg at the same time, so there is no lapse in treatment? And how long until Zoloft starts working?

Yes, if doc agrees: Always discuss your plan of care with ur doc. It's most common 4 docs 2 recommend that patients reduce the dose of one med while they transition on to a new one, for the reason u mentioned -- no lapse. Docs call this a "cross taper". Unclear how long it will take for zoloft (sertraline) to work. Some pts feel btr in just a few days, while others may need up to 8 wks on the right dose. Ring ur doc to discuss :) ...Read more

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On Effexor (venlafaxine) XR 150 mg and need to wean off. Have not been successful in the past because of horrible withdrawal symptoms. What can I do? What vitamins?

On Effexor (venlafaxine) XR 150 mg and need to wean off. Have not been successful in the past because of horrible withdrawal symptoms. What can I do? What vitamins?

Gradual: Need guidance by physician

gradual dosage reduction guided by the emergence with discontinuation symptoms

in some circumstances, due to its long half life, using fluoxetine as the agent to use as for the withdrawal process is considered. ...Read more

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I am suffering from G A D.since birth. I am on effexor 300mg valium 10mg since 1979, amitriptyline75mg for pain and trazodone 100mg. My dr stated months ago that there is no cure but this week we wants me to wean off them. My phys wants to stay on them?

I am suffering from G A D.since birth. I am on effexor 300mg valium 10mg since 1979, amitriptyline75mg for pain and trazodone 100mg. My dr stated months ago that there is no cure but this week we wants me to wean off them. My phys wants to stay on them?

GAD: Please do not change your medications w/out the guidance of your doctor. Choose one, perhaps your primary care doctor, since he/she looks at your overall health picture. Have you seen a psychologist for other kinds of help such as clinical hypnosis (see www. Asch. Net), biofeedback, or psychotherapy? All if these can help w/anxiety and pain. Peace and good health. ...Read more

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I recently weaned off Effexor (venlafaxine) XR by taking Prozac 10 mg and from dropping from 50-25mg seroquel for a week then 12.5mg seroquel then stopped both Prozac and seroquel on 5/13.I can't sleep now, help!

I recently weaned off Effexor (venlafaxine) XR by taking Prozac 10 mg and from dropping from 50-25mg seroquel for a week then 12.5mg seroquel then stopped both Prozac and seroquel on 5/13.I can't sleep now, help!

Talk w/your doctor: This question is best answered by your own doctor who prescribed you the medications and then tapered them. If you're having difficulty, please contact him/her. S/he may want you to continue a low dose of seroquel (quetiapine) for a little longer -- but I don't know what symptoms you were having in the first place. Symptoms can return when medication is stopped. Your doctor knows you best, & can help. ...Read more

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Is it possible to be weaned off the Effexor and get my body back to normal? I have been taking Effexor for years. A doctor recently increased my dosage to 300mg from 75mg. I have major digestive issues (constipation), I can't loose weight no matter what I

Is it possible to be weaned off the Effexor and get my body back to normal? I have been taking Effexor for years. A doctor recently increased my dosage to 300mg from 75mg. I have major digestive issues (constipation), I can't loose weight no matter what I

Serotonin: Serotonin discontinuation symptoms, associated with abrupt discontinuation of Effexor (venlafaxine), could be related to it`s short half life. In most cases, this may be minimized by slowly tapering the dosage. Another strategy would be using a low dosage of a long acting ssri like fluoxetine. The physical symptoms include problems with balance, gastrointestinal and flu-like symptoms, and sensory and sleep disturbances. Psychological symptoms include anxiety and/or agitation, crying spells, irritability and aggressiveness. ...Read more

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Can u take lorazepam for an attack if u are taking clonazepam twice daily? And I'm just starting Zoloft and still taking Effexor (venlafaxine) weaning off

Benzos are Dangerous: No. Why would you have two drugs of the same class? Does your prescribing physician know you are on all of this medication? The goal is to find a way to prevent anxiety. Benzos do not cure, treat or prevent anxiety. They calm you down; they are sedating? And they are extremely addictive. ...Read more

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Seroquel is not helping with insomnia. It was for about a week, but loss of sleep is creeping up again since I weaned off Effexor (venlafaxine) and prozac?

Seroquel is not helping with insomnia. It was for about a week, but loss of sleep is creeping up again since I weaned off Effexor (venlafaxine) and prozac?

Call your doctor: Please contact your physician about this asap. S/he may need to adjust your seroquel (quetiapine) dose. If you have bipolar disorder, the sleep loss could be impending hypomania or mania. Your doctor will be best able to advise you. Be well. ...Read more

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150mg Venlafaxine and 20mg Mianserin. Mianserin is what I would like to wean off. Please help.

Weaning medication: Both of venlafaxine and mianserin are have withdrawal symptoms of nausea, vomiting, diarrhea, anxiety, panic attacks, fatigue, lack of appetite, dizziness/room spinning, headache, insomnia, etc. And the venlafaxine has a feeling described as "brain zaps" if stopped too fast. So neither med is the kind to manipulate by yourself. See the doctor who is prescribing them and work with her/him. ...Read more

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How to wean off venlafaxine 300 mg's to start impramine?

How to wean off venlafaxine 300 mg's to start impramine?

Consult with your dr: Weaning off meds is not easy. There are several ways to do what you asking, but the process needs to be supervised by a specialist. ...Read more

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Can effexor treat schizophrenia?

Possibly helpful: Effexor is an SNRI used to treat depression, can be added sometimes. Treatment of schizophrenia today is most often using second-generation antipsychotic medications. There are about a dozen of these, and about a half dozen first-generation antipsychotics. The newer drugs have less side effects, but the older ones are cheaper. Consult with your doctor to determine which may be best for you ...Read more

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Can I take flexeril if I took Effexor earlier?

Can I take flexeril if I took Effexor earlier?

Be careful!: In general, those two medicines taken at the same time can give you a condition called serotonin syndrome. Therefore, Usually is not recommended that you take them together. ...Read more

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Does effexor (venlafaxine) help with opiate wd?

Does effexor (venlafaxine) help with opiate wd?

Not really: That medication will help underlying depression that may be secondary to or certainly an underlying condition with a history of drug use. Check with your Doctor as there are other meds that can help with opiate withdraw, that can be prescribed in a plan of care designed specifically for you by your doctor. Best wishes. ...Read more

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Does Effexor (venlafaxine) affect male fertility?

Yes: There is a risk of ejaculatory problems and low sperm counts with use of effexor (venlafaxine). Best advice is to seek an evaluation with your fertility doctor. ...Read more

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Can I take Effexor (venlafaxine) XR and synthroid?

Can I take Effexor (venlafaxine) XR and synthroid?

Yes: Yes. Ideally synthroid (thyroxine) should be taken on an empty stomach 30 min. Before food or other meds. ...Read more

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Can I drink coffee while takin effexor (venlafaxine)?

Yes: There's no special restriction about drinking coffee while taking Effexor (venlafaxine). Of course, the caffeine may make you anxious or jumpy, but this would be true with or without the medication. In addition, Effexor is sometimes experienced as mildly stimulating itself, so this could add to the caffeine effect. ...Read more

Effexor (Definition)

Venlafaxine is a non-tricyclic which is a kind of serotonin-norepinephrine reuptake inhibiting drug (atypical anti-psychotic ...Read more