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Doctor insights on: How To Treat Factor Viii Deficiency

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What is the treatment for factor viii deficiency?

What is the treatment for factor viii deficiency?

Factor VIII: Concentrate. Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma. Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding. The drug is given intravenously. ...Read more

Dr. James Lin
26 doctors shared insights

Factor Viii Deficiency (Definition)

Factor VIII deficiency (also known as Hemophilia A) is disease of the blood in which a person lacks a protein necessary for clotting. These patients are prone to excessive ...Read more


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How to treat pernicious anemia?

How to treat pernicious anemia?

B-12 deficiency: Unless there is an intestinal parasite, we usually just do blood studies to confirm and supplement vitamin b-12 using 1000 mcg injected monthly, i.M. Some pts will absorb sufficient amounts by mouth or intranasal routes, but most efficient to inject. ...Read more

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How can deficiency to vitamin D3 cause depression?

How can deficiency to vitamin D3 cause depression?

Not really known yet: Depression is a complex problem & no one really knows the cause of any type of depression! many people get depressed in winter; it was thought to be due to lack of light but may be due to low vit d- giving d works better than light therapy! there are vit. D receptors in the brain & it may help regulate the levels of serotonin. See http://www.Vitamindcouncil.Org/health-conditions/depression/. ...Read more

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How to treat alpha1-antitrypsin deficiency/emphysema?

How to treat alpha1-antitrypsin deficiency/emphysema?

Enzyme replacement: The enzyme can be replaced by monthly IV treatments to raise blood levels to adequate levels. ...Read more

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I have type 2 von willebrands, severe, unknown subtype. I only respond to humate p (factor viii and von willebrand factor). Is there anything else i can take to help with minor bleeds. ?

There are options: There are two other possibiliries that are approved "non-replacement" therapies for the treatment of VWD type 2a, in addition to humamte p there is Alphanate sd/ht. The other is called Koate dvi (factor viii) but this one is used in an off lable fasion for vwd. Read starting at page 50 here for more information. Only your hematologist should make any changes. http://www.nhlbi.nih.gov/guidelines/vwd/vwd.pdf. ...Read more

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How can I treat leiden factor v?

How can I treat leiden factor v?

Pls. clarify: Do you mean factor v deficiency? Someone with this deficiency and had blood clots would likely be prescribed a blood thinner for lifetime. If there is a life-threatening blood clot, they may receive a tranfusion of plasma (blood liquid). Plasma does not last long in the body. ...Read more

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Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Yes, in men: Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm. ...Read more

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How do you treat a pregnancy with the factor v leiden mutation?

How do you treat a pregnancy with the factor v leiden mutation?

Lovenox (enoxaparin): The woman needs to be on long term Heparin treatment. Usually a subcutaneously injected preparation is used. ...Read more

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How to prevent g6pd deficient to become leukemia?

How to prevent g6pd deficient to become leukemia?

No relation: Individuals with g6pd deficiency are not at higher risk to develop leukemia than general population. ...Read more

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What does Acquired Coagulation Factor Deficiency mean relating to surgery?

What does Acquired Coagulation Factor Deficiency mean relating to surgery?

Higher risk of bleed: ... is a concern. A select factor deficiency (missing, depleted or inhibited for various reasons) can adversely impact at least 1 of 3 pathways that prevent bleeding. Some factor deficiencies are more serious than others. The surgeon usually consults a hematologist in these cases so that there are no problems during or around the surgery. No excess bleeding w/ any prior surgery = good omen. ...Read more

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How is 'pernicious anemia' treated?

How is 'pernicious anemia' treated?

With B12!: Taken by injection, or with 2500 mcg oral B12. Can be associated with iron deficiency of gastric acid production is reduced! ...Read more

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How to feed the child to prevent iron-deficiency anemia?

How to feed the child to prevent iron-deficiency anemia?

Oral iron supplement: You may give the child oral iron supplement. You may look of foods, e.g., cereals, with iron supplement. ...Read more

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What sort of disorder is factor viii deficiency?

R/o vWD: A patient with von willebrand's disease, which is extremely common and usually mild, may be told they have factor viii deficiency. ...Read more

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How to treat a person with protein deficiency having gout?

How to treat a person with protein deficiency having gout?

See your doctor: If there is an underlying medical reason for your protein deficiency, medical treatment will be in order. If it is due to malnutrition or crash dieting, getting the right protein in the diet and/or supplementation might help. It is controversial, but in patients who do not take in enough protein and/or calories, muscle catabolism takes place before burning fat. ...Read more

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How is testosterone deficiency diagnosed?

How is testosterone deficiency diagnosed?

History and Labs: History indicates this may be present. Any male suffering fatigue and having erectile dysfunction should have testosterone levels. I like to use both total testosterone and free testosterone levels to verify deficiency. I also get a psa (prostate cancer blood test) to make sure prostate cancer is not present prior to starting testosterone replacement in someone proven to need it. ...Read more

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How to help someone with immune deficiency to prevent infection?

How to help someone with immune deficiency to prevent infection?

Education: Different measures are indicated according to the type and degree of immunodeficiency. All immunodeficient patients should avoid contact with obviously sick individuals. Washing hands and avoiding crowded environments. Antibiotic in prophylaxis doses are a common indication for some conditions. Antibody replacemtns is indicated for those with proven antibody deficiency. ...Read more

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What are the tests for factor viii deficiency?

What are the tests for factor viii deficiency?

Blood tests and: Family history. Blood tests for levels of factor viii are available, though simpler tests, e.g., PTT with appropriate family history may be sufficient. ...Read more

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What sort of disorder is factor viii deficiency?

R/o vWD: A patient with von willebrand's disease, which is extremely common and usually mild, may be told they have factor viii deficiency. ...Read more

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What are the symptoms of factor viii deficiency?

What are the symptoms of factor viii deficiency?

Bleeding/bruising: Factor viii deficiency or hemophilia- is a bleeding disorder. It is hereditary in most cases . The symptoms would be spontaneous bleeding- either in the joints, skin/gum, or other places etc or prolonged bleeding. The severity of bleeding will depend on how low the level of the factor viii is.. Usually the bleeding episodes will manifest at early age. Discuss further with your hematologist. ...Read more

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Can you tell me if someone is heterozygous w/ the hemophilia gene, is it possible for them to still have factor viii deficiency?

Yes, in men: Hemophilia is a sex linked disorder and men develop the disease when there only x chromosome has the defective gene. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/000538.htm. ...Read more

See 1 more doctor answer
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What is the treatment for factor viii deficiency?

Factor VIII: Concentrate. Factor viii is prepared by recombinant technology, though it may also be extracted from human plasma. Depending on the severity of deficiency, factor viii may be given prophylactically or to treat episodes of bleeding. The drug is given intravenously. ...Read more

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What to do along with Factor VIII for severe hemarthrosis along with large joint effusion of knee in patient with Hemophilia A?

What to do along with Factor VIII for severe hemarthrosis along with large joint effusion of knee in patient with Hemophilia A?

Xfusion with factor-: -Vlll, then aspiration of the joint. Chronic hemarthrosis destroys the articular cartilages. It consumes O2, & does not allow it 2 B nourished. Cartilages only O2 comes from the joint fluid, but it's not available since the inflammatory reaction 2 the blood consumes it ...Read more

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Factor viii inhibitor in hemophilia? What is a factor viii inhibitor?

Antibody to factor: Viii protein. People who are deficient in factor viii, i.e., have severe hemophilia, are treated with infusion of factor viii. Some make antibodies to factor viii and inhibit its function and are called factor viii inhibitors. Rarely non-hemophiliac can also develop such an inhibitor. ...Read more

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Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation?

Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation?

PTT and ARR: Are a mildly elevated PTT and mildly elevated Coagulation Factor VIII Activity, as all as a high ALDO/PRA RATIO something to be concerned about and is there a correlation? ANS: no and No. I specialize in ARR problems. Happy to do 2nd opinion. ...Read more

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What does it mean if I have a high factor viii assay value? E.G. 174%?

What does it mean if I have a high factor viii assay value? E.G. 174%?

Not hemophilia: Probably were being tested form blood clotting disorders. This is a test for hemophilia a (which you do not have based on this test). ...Read more

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Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

Why plasmapheresis is used to remove factor viii; could this be useful in a procoagulable state?

No.: Plasmapheresis removes all the clotting proteins, including factor viii, but the body rapidly replaces what is taken out. Usually all proteins are back to their usual levels within 24 hours. This would not be long enough to provide meaningful anti-coagulation. ...Read more

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What is the prognosis for a person suffering from severe hemophilia, but getting regular factor viii replacement therapy?

What is the prognosis for a person suffering from severe hemophilia, but getting regular factor viii replacement therapy?

Excellent: One of my new colleagues has almost no factor viii but leads a near-normal life (no boxing or tackle football) on replacement. We can be thankful for biotechnology that has made this possible. ...Read more

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What are the functions of factor viii? What if you're low on your factor viii?

Blood clotting: Factor viii is a clotting factor. This is one of many that help you stop bleeding from a cut. If you are low on factor 8, then you will bleed longer than someone who has normal factor 8. The associated condition is called hemophilia a. Treatment is done by replacing the factor 8 when necessary, such as after a trauma or surgery. In severe cases, you may be given factor 8 regularly for prevention. ...Read more

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What test can be done for someone with thrombophilia factor viii?

What test can be done for someone with thrombophilia factor viii?

Get exact diagnosis: Hemophilia with factor viii deficiency is the most common kind. These people today for the most part live near-normal lives thanks to biotechnology. There is talk of a thrombophilia (excess blood clotting / deep vein thrimbi) due to elevated levels of factor viii; this is a subspecialty hematologist question. ...Read more

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I just found out my daughter has a factor viii of 38. What does this mean? Doctor said to take her to hematologist.

I just found out my daughter has a factor viii of 38.   What does this mean?  Doctor said to take her to hematologist.

Little low: May have hemophilia a. Usually seen in men. Women can be carriers. Can have minor bleeding or asymptomatic. I agree that she needs to see a hematologist. She may require treatment with a drug called desmopressin if surgery is required. Check out site. http://www.ucdenver.edu/academics/colleges/medicalschool/centers/hemophiliathrombosis/resources/documents/guide%20to%20mild%20hemophilia.pdf. ...Read more

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What does a low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

What does a  low von willebrand factor (vwf) ag: 33 %, low vwf activity: 29 % and factor viii activity: 52 % result mean?

VWD: First of all, these test need to be repeated at least one more time, prederably while you are off all medications. If persistently low, this may mean that you have von willibrand disease (VWD) which is a bleeding disorder. These are several types of VWD and more testing is needed to determine the type. You need to see a hematologist for this. Avoid any surgery and trauma. ...Read more

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I have type 2 von willebrands, severe, unknown subtype. I only respond to humate p (factor viii and von willebrand factor). Is there anything else i can take to help with minor bleeds. ?

There are options: There are two other possibiliries that are approved "non-replacement" therapies for the treatment of VWD type 2a, in addition to humamte p there is Alphanate sd/ht. The other is called Koate dvi (factor viii) but this one is used in an off lable fasion for vwd. Read starting at page 50 here for more information. Only your hematologist should make any changes. http://www.nhlbi.nih.gov/guidelines/vwd/vwd.pdf. ...Read more