Doctor insights on:
How To Treat Antiphospholipid Syndrome Quickly
I have antiphospholipid syndrome,I had a sagital sinus thrombosis 1 yr ago,for the past 4 weeks I've had severe earpain, not treatable with antibiotic?
Failure of other Tx: Apls (antiphospholipid antibody syndrome) if necessary can be treated first with steroids like prednisone. Sometimes just being on a blood thinner is enough to avoid blood clots that it can cause or miscarriages. Other treatments like Rituxan (rituximab) (antibody) have been used especially if low platelet counts are seen. If these initial tx fail, doctors may resort to chemo drugs like cyclophosphamide. ...Read moreSee 1 more doctor answer
What are common neurological symptoms for seronegative antiphospholipid syndrome and once treated do these symptoms go away?
Yes and no!: First, all acla are of not the same significance, since the igm anticardiolipin ab is more likely to cause blood vessel blockage than the igg, which is worse than the iga! second, if a mini-stroke has occured, there may be complete resolution. If a major stroke has occurred then resolution will be incomlete at best. Individuals with antiphospholipid syndrome should be anticoagulated. ...Read more
Heparin: Risk for miscarriages have been related and will be significant in patient with anti phospholipids syndrome. Heparin will be needed during prenancy to reduce risk for miscarriages. It is safe to use Heparin during pregnancy. You will need to be seen by your ob/perinatologist and will likely be referred to a hematologist for your high risk pregnancy. ...Read more
Blood clots: Antiphospholipid Syndrome (APS) can exist on its own or in association with another autoimmune condition such as lupus. It is caused by antibodies that increase the risk of blood clots. These antibodies also interfere with routine laboratory tests of blood clotting by binding to phospholipids, hence the name. The symptoms of APS can include blood clots, Raynaud's and pregnancy loss. ...Read moreSee 2 more doctor answers
Short description: It involves arterial or venous clotting or specific pregnancy complications, with laboratory evidence of anti-phospholipid antibodies. Autoantibodies, meaning produced and directed against one's self, are to plasma proteins (many:) altering normal clotting leading to thrombus (clot) and/or pregancy complications like fetal death, recurrent early pregnancy loss, eclampsia, and others. ...Read more
Lupus, stress.: Systemic lupus erythematosus, chronic/acute severe stress and genetic predisposition all conspire to lead to antiphospholipid antibody syndrome. This is a very rare but devastating disorder that can have horrible perinatal outcomes with each pregnancy. Considered an autoimmune disorder, apls may have its etiological underpinnings in maternal-fetal cell trafficking, as most autoimmune conditions. ...Read more
Autoimmune: Autoimmune means your body produces antibodies - cells that attack your own body. In antiphosopholipid syndrome the antibody which is made provokes blood clots (thrombosis) in both arteries and veins as well as pregnancy-related complications such as miscarriage, stillbirth, preterm delivery, or severe preeclampsia. ...Read moreSee 4 more doctor answers
Complex problems: The manifestations of aps range from having no symptoms at all to catastrophic, disastrous clotting affecting multiple organs leading to death within days. Many will present with blood clots, some with skin changes, others with low platelets or women will have repeated spontaneous miscarriages. Another autoimmune disorder may also be diagnosed such as lupus erythematosus. See:http://www.Apsfa.Org/. ...Read more
Short description: It involves arterial or venous clotting or specific pregnancy complications, with laboratory evidence of anti-phospholipid antibodies. Autoantibodies, meaning produced and directed against one's self, are to plasma proteins (many:) altering normal clotting leading to thrombus (clot) and/or pregancy complications like fetal death, recurrent early pregnancy loss, eclampsia, and others. ...Read moreSee 1 more doctor answer
Antiphospholipid antibodies: Antiphospholipid antibodies are components in one's blood that can increase the risk of blood clots especially in the smallest blood vessels called capillaries. These individuals are prone to deep venous thrombosis in the leg and potentially pulmonary embolus in the lungs. ...Read moreSee 2 more doctor answers
There are a few...: The criteria for the diagnosis of aps is based upon both clinical findings(what happens to you) and laboratory findings(results of blood tests). Some of the clinical findngs are a history of blood clots; fetal death over 10 weeks; delivery under 34 weeks due to preeclampsia; 3 or more recurrent miscarriages. Since aps can adversely affect a pregnancy, you need to discuss with your physician. ...Read moreSee 1 more doctor answer
Hard to know: True anti phospholipid syndrome is rare we only diagnose this problem when people have a history of clotting problems the diagnosis has now been extended to people with 2 or more miscarriages. The diagnosis needs to be carefully considered if diagnosed Aspirin or Heparin maybe useful. ...Read more
Not likely, but...: It is possible but unlikely.Get a more detailed answer ›
Pregnancy outcome: Individuals with antiphospholipid syndrome may be at an increased risk of first trimester recurrent pregnancy loss. Treatments are available though to improve outcome. Make sure your OB or your fertility specialist knows so he/she can address appropriately. ...Read moreSee 2 more doctor answers
Common young/mid-age: Aps is commonly seen in the young and middle age group but can be seen in the pediatric and elderly population also. Since aps may be a part of sle (lupus), a sizable number of aps patients are young in common with the sle population. There is a female preponderance also. ...Read more
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