Doctor insights on:
How To Treat Antiphospholipid Syndrome Quickly
I have antiphospholipid syndrome,I had a sagital sinus thrombosis 1 yr ago,for the past 4 weeks I've had severe earpain, not treatable with antibiotic?
Antiphospholipid antibodies are components in one's blood that can increase the risk of blood clots especially in the smallest blood vessels called capillaries. These individuals are prone to deep venous thrombosis in the leg and potentially pulmonary ...Read more
Failure of other Tx: Apls (antiphospholipid antibody syndrome) if necessary can be treated first with steroids like prednisone. Sometimes just being on a blood thinner is enough to avoid blood clots that it can cause or miscarriages. Other treatments like Rituxan (rituximab) (antibody) have been used especially if low platelet counts are seen. If these initial tx fail, doctors may resort to chemo drugs like cyclophosphamide. ...Read moreSee 1 more doctor answer
What are common neurological symptoms for seronegative antiphospholipid syndrome and once treated do these symptoms go away?
Yes and no!: First, all acla are of not the same significance, since the igm anticardiolipin ab is more likely to cause blood vessel blockage than the igg, which is worse than the iga! second, if a mini-stroke has occured, there may be complete resolution. If a major stroke has occurred then resolution will be incomlete at best. Individuals with antiphospholipid syndrome should be anticoagulated. ...Read more
Heparin: Risk for miscarriages have been related and will be significant in patient with anti phospholipids syndrome. Heparin will be needed during prenancy to reduce risk for miscarriages. It is safe to use Heparin during pregnancy. You will need to be seen by your ob/perinatologist and will likely be referred to a hematologist for your high risk pregnancy. ...Read more
Blood clots: Antiphospholipid Syndrome (APS) can exist on its own or in association with another autoimmune condition such as lupus. It is caused by antibodies that increase the risk of blood clots. These antibodies also interfere with routine laboratory tests of blood clotting by binding to phospholipids, hence the name. The symptoms of APS can include blood clots, Raynaud's and pregnancy loss. ...Read moreSee 2 more doctor answers
Short description: It involves arterial or venous clotting or specific pregnancy complications, with laboratory evidence of anti-phospholipid antibodies. Autoantibodies, meaning produced and directed against one's self, are to plasma proteins (many:) altering normal clotting leading to thrombus (clot) and/or pregancy complications like fetal death, recurrent early pregnancy loss, eclampsia, and others. ...Read more
Lupus, stress.: Systemic lupus erythematosus, chronic/acute severe stress and genetic predisposition all conspire to lead to antiphospholipid antibody syndrome. This is a very rare but devastating disorder that can have horrible perinatal outcomes with each pregnancy. Considered an autoimmune disorder, apls may have its etiological underpinnings in maternal-fetal cell trafficking, as most autoimmune conditions. ...Read more
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