Doctor insights on:
How To Know If Ovarian Cancer Has Spread
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Pelvis & abomen: Commonly when advaced spreads in the abdomen affecting the peritoneum producing increased intra pelvic and abdominal fluid. As most cancers may spread to liver, lung, brain, bone. Most ovarian cancer produce symptoms only in advanced stages with nonspecific sensations of increased belly or intraabdominally discomfort. Ca 125 is not a screening test because of so many false positives and negatives. ...Read moreSee 1 more doctor answer
Depends on surgery: Ovarian cancer has a high incidence of metastasis. When it occurs surgical debuling is the procedure of choice. The omentum becomes involved due to presence of TGF-B producing caking and leading to ascites followed by diaphragm and small bowel seeding. Best results with total omentectomy and debulking to no lesion left that is larger than 1 cm or smaller. Chemo then can be effective. ...Read more
Can be helped: A radical resection of the omentum essentially removing the entire cake of tumor is performed eliminating vasucular permeability factor that leads to ascites. All peritoneal nodules are resected to smaller than 1 cm. and patient then placed on chemotherapy. Occassionally hyperthermic peritoneal chemotherapy lavage employed. Often patients may be cured if not helped in terms of survival. ...Read more
What are my chances of getting ovarian cancer? My aunt had something that spread through her abdomen but we never heard what it was before she died.
It is a cancer which arises from the ovary. This cancer is typically silent, producing little or no symptoms till it spreads, first into the pelvic area and later into the peritoneal cavity leading to fluid accumulation(ascites) which is often the first symptom. Despite its late presentation, there is a reasonable treatment for it, with some long term survivors even ...Read more
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