Doctor insights on:
How Soon Can Holoprosencephaly Be Detected
Undivided brain: Most of us have 2 halves in our brain, known as "hemispheres". Holoprosencephaly (HPE) is abnormal division of the embryo's brain and lack of separation of the cerebral hemispheres. HPI can be mild to severe and can cause defects in the development of the face and in brain structure and function. ...Read more
When the embryo's forebrain does not divide to form bilateral cerebral hemispheres (the left and right halves of the brain), it causes defects in the development of the face and in brain structure and function.
In less severe cases, babies are born with normal or near-normal brain development and facial deformities that may affect the eyes, nose, and upper lip. The condition can be mild or severe. ...Read more
Lobar Holopreosenceh: I believe you are referring to Lobar Holopreosencehaly in which the brain is not formed well leading to severe mental retardation. This is a rare condition from failure of the brain to completely divide into two separate halves. Many parts of the entire brain may be fused and not allow normal function. This may be as a result of some chromosomal disorders. A more complete descriptionfromgeneticist ...Read more
Undetermined: Potential depends on the severity of the defect and associated features. Many die before birth and most have a brief existence. The defect involves a great range from very major to minor, with longevity matching the degree of defect. See www. Ninds. Nih. Gov/disorders/holoprosencephaly for more information ...Read more
Maybe none: If I am understanding the question correctly, you're asking if someone who has a child with holoporsencephaly has genetic problems themselves. As dr ferfuson said, this problem is sometimes associated with genetic problems *in the kid.* children with these types of problems can be born from perfectly normal parents. It just happens. To be sure, parents can get tested if they want. ...Read more
Yes, some.: The fetal/neonatal brain has enough plasticity to allow for mild/moderate porencephalic cases to function at an acceptable level after a long and hard road to recovery. Lissencephaly and holoprosencephaly are developmental disorders of the brain anatomy and usually are manifested with recalcitrant seizures, profound neurodevelopmental delay and limitations to independent living. ...Read more
It can be detected during the pregnancy, but by the mean of the obstetrical ultrasonography and depends on the skills of the technician performing the procedure.
The other screening tests performed during pregnancy, may predict some of the chromosomal disorders, associated with holoprosencephaly, such as trisomy 13. ...Read more
I am 35 weeks pregnant and had two abortions and one induced abortion at 5 months due to holoprosencephaly child that was very painful want to know how much painful this time ll be to deliver a baby and whether baby will come on time or earlier?
Labor hurts: Most women find labor a lot of work and painful. They are blessed with selective forgetting since most are willing to do it again later. Your history of prior abortions will have no particular impact on the process. Labor will start when it decides to. Only about 5% deliver on their due date while 80% + deliver within 2 wks of it. ...Read more
Here are some. ..: The ED-related symptoms may be slowly developing and subtle since ED results from multiple factors including aging, diseases, drugs, low-T, etc. So, men with ED may start noticing less energy, ability, & endurance to conduct daily personal and occupational chores and tasks than before with subtle worsening; they may get SOB easier than before and require more resting. ...Read more
Many possibles: ED can have many sources. The most common by far is psychological. While difficult to hear, there usually is a underlying issue that impedes your erections. If you can masturbate without difficulty, then it is probably not a physical problem. There are also physical problems that can cause it, high blood pressure, certain medications, peripheral vascular disease. See your doctor for a work up. ...Read more
Need eval: At 25 erectile dysfunction is more unusual. If you have had surgery or injury then your potential concerns are valid. However you need to have labs done and questioned carefully to clarify cause. I hesitate giving a "fix it" without knowing what the true problem is. If it is physiological then finding out underlying cause is essential. ...Read more
Depends on "ED": If you are using ed to mean "erectile dysfunction": the ssri's can cause ed as a side-effect in between 5-50% of men - depending on the agent involved; the ed usually resolves when the ssri is stopped; also, there are meds which can be taken to reduce the ed. If you are referring to "eating disorder": ssri's are often used in the treatment of anorexia and bulimia. ...Read more
No, but...: Everything we do in life / medicine is just to modify something for working better, but always comes with a price. Any surgical care is considered as the last resort of care after failing to respond to drug, physical therapy, lifestyle change, injection, etc. So, ed-related surgery may be penile implant, penile straightening for peyronie's disease, just like hip/knee replacement for djd... ...Read more
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