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Doctor insights on: How Safe Is Reglan Used For Long Term Gastroparesis

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How safe is reglan (metoclopramide)? Used for long term gastroparesis.

How safe is reglan (metoclopramide)? Used for long term gastroparesis.

Risky: Maximum recommended duration of Reglan (metoclopramide) use is 12 weeks. It's because of the increases risk with the long term use including extrapyramidal side effects such as tardive dyskinesia, which is an involuntary movement disorder. ...Read more

Reglan (Definition)

Metoclopramide increases emptying of food from the stomach and decreases symptoms of nausea, vomiting, heartburn, and fullness,. It should ideally be taken 30 minutes before meals. It's use in pregnancy should be reserved for severe conditions where the risks to the baby of not treating exceed the potential ...Read more


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How long after stopping bydureon (exenatide) should nausea and gastroparesis end? Should I discuss reglan with md?

How long after stopping bydureon (exenatide) should nausea and gastroparesis end?  Should I discuss reglan with md?

Weeks: Bydureon (exenatide) takes many weeks to start working, and also many weeks to get out of your system once you stop it. It will make gastroparesis worse. Reglan can be of some benefit in people with gastroparesis, but it has side effects after you have been on it for some time. ...Read more

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I was recently diagnosis with gastroparesis a few weeks ago and the medicine im on iz reglan (metoclopramide). Whats the time to the pills?

I was recently diagnosis with gastroparesis a few weeks ago and the medicine im on iz reglan (metoclopramide). Whats the time to the pills?

With meals: Not sure what the question is asking but if you are taking this med for gastroparesis, you should take it 30 min before your big meals, so essentially, 3x/day. ...Read more

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On 100mg Zoloft and on reglan (metoclopramide) for gastroparesis, could Zoloft be contributing to the low motility issues?

On 100mg Zoloft and  on reglan (metoclopramide) for gastroparesis, could  Zoloft be contributing to the low motility issues?

Zoloft (sertraline) and motility: Gastroparesis is such a severe condition that anything and everything that can be tried to help should be; with that said zoloft (sertraline) seems to have effect on motility in individiauls. If you can handle going off the med after a discussion with your dr you should give it a try to see if it helps - even a little bit good luck! ...Read more

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Should I take reglan/domperidone for gastroparesis?

Domperidone: "Food and Drug Administration (FDA) stresses that domperidone is not an FDA-approved drug, and that it may not be legally marketed in the US." " FDA's concern about the potential health risks associated with the use of domperidone in lactating women. These risks include cardiac arrhythmias, cardiac arrest, and sudden death." ...Read more

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Told my gastroparesis can't be treated due to being allergic to reglan (metoclopramide). My t 1/2 time = 342min . What other options can I ask my dr about?

Told my gastroparesis can't be treated due to being allergic to reglan (metoclopramide). My t 1/2 time = 342min . What other options can I ask my dr about?

Lots of options...: Depending on the nature of your gastroparesis (dysmotility versus partial obstruction) treatment options may include: gastric pacemaker insertion, pro-motilin drugs like Erythromycin (yes, the antibiotic), experimental protocol therapies (there are several), and medications that are not fda-approved but available outside the us (like zelnorm, domperidone). Discuss merits of each with your doctor. ...Read more

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Thrown up almost every day for a year. In sept I was diagnosed W/ gastroparesis. What else could cause this? Diet changes and meds like Reglan (metoclopramide) no help

Many things: can cause gastroparesis. It can be from anything that can affect the innervation(nerve system) of the stomach. That can range from hormonal problems like diabetes or thyroid disease, infections, autoimmune diseases, nutritional disease and more. ...Read more

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Two docs have told me TD resulting from Reglan (metoclopramide) use for idiopathic gastroparesis is reversible, and two say it's not. Who's correct?

Two docs have told me TD resulting from Reglan (metoclopramide) use for idiopathic gastroparesis is reversible, and two say it's not. Who's correct?

All 4 are correct!: Bazinga! Everyone wins here except the patient who ends up with the permanent side effects of TD. I know cuz I've seen it happen & it's not fun. Darn thing is, we can't predict who'll reverse & who won't. If it reverses when med's stopped then? REVERSIBLE! If it doesn't then, NOT REVERSIBLE. Better question- MUST you TREAT? The answer may surprise you. Write me: www.healthtap.com/drsaghafi ...Read more

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I have severe gastroparesis, anyone heard about any natural supplements to help with this? I certainly don't want to take reglan! ;)

Some ideas proposed: Ginger accelerates gastric emptying. The dose used was three capsules containing a total of 1, 200 mg of ginger acupuncture has been shown in randomized trials to be effective for gastroparesis.Erythromycin has been shown to affect gastroparesis, the oral form is usually given in lower dosages than required for antibiotic effects (ie, 150-250 mg PO 3 to 4 times a day given before meals. Good luck. ...Read more

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I was diagnosed with silent reflux & gastroparesis. I was prescribed Reglan (metoclopramide) . Having heart palps and stopped reglan (metoclopramide). Can 500 mg cause this too?

I was diagnosed with silent reflux & gastroparesis.  I was prescribed  Reglan (metoclopramide) .  Having heart palps and stopped reglan (metoclopramide).  Can 500 mg  cause this  too?

Check dosage: Side effects of reglan (metoclopramide) can be quite serious, but heart palpitations is not one of them. However, I am concerned about the dosage you are saying. Is that over 24 hr? 10mg every four hours is the higher end of normal, and Reglan (metoclopramide) is not a medicine you want to take for long periods of time. Please see the Rx'ing MD regarding this, and to go over your other medications and symptoms. ...Read more

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I have gastroparesis which the pacer has been ineffective, so since april i take 80mg of reglan (metoclopramide) a day, could this cause intense nerve pain in my legs?

Unlikely: You are taking very high dose of reglan (metoclopramide). I don't think you're severe leg pain is related to reglan (metoclopramide). But you should discuss with your gastroenerelogist to change your treatment of gastroparesis if possible. ...Read more

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Starting out on Prozac (20mg daily), Zofran(8mg,twice daily), and Cyclizine (before bed) for gastroparesis, thoughts? Reglan (metoclopramide) didn't work out.

Follow GI suggestion: Gastroparesis is difficult to treat,Rx is individualized. Some times Domeperidome ( not available in US, but available in Canada) works. Ginger tea and chewing dry salted Ginger may help Nausea. ...Read more

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I have gastroparesis. I'm on Reglan&Flagyl. I feel like I'm starving but just throw up. I wake up at night drenched in sweat shaky. What can I do?

I have gastroparesis.  I'm on Reglan&Flagyl. I feel like I'm starving but  just throw up. I wake up at night drenched in sweat shaky. What can I do?

Tough problem: Hi. Why do you have gastroparesis? Diabetes is the most common cause, but there are many causes. Gastroparesis is tough to treat effectively. If you are diabetic, waking up drenched in sweat and shaky makes me suspect nocturnal hypoglycemia. That's a lot to have assume, and I would have to think you'd tell us if you were on insulin. Otherwise, infections and certain malignancies should be consider ...Read more

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EGD shows gastroparesis.Allergic to Reglan (metoclopramide) & Erythromycin.Told to manage with diet.Is that enough?

EGD shows gastroparesis.Allergic to Reglan (metoclopramide) & Erythromycin.Told to manage with diet.Is that enough?

Define "allergic": True "drug allergy", or "adverse drug reaction", often times it is the latter, side effects are interpreted as "allergy" to a certain drug, we avoid it and lose the benefit. Kindly write down what exactly were your symptoms when had the drug, how long after administering it, and how did the symptoms go away for each dug separately,show them to your doctor.You can see an allergist to sort it out ...Read more

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I have gastroparesis. Md wants reglan (metoclopramide) but I have a family history of Parkinson's and a personal history of depression and anxiety. What about the gastric sleeve?

No: Surgery, especially sleeve gastrecyomy, would make the problem of gastroparesis much worse. Medication is a much superior choice for this diagnosis. Rarely subtotal gastrectomy as a last resort. ...Read more

Dr. Vivek Huilgol
420 doctors shared insights

Gastroparesis (Definition)

A condition where the stomach is not able to empty its contents as effectively, but there is ...Read more


Dr. Marcus Reidenberg
247 doctors shared insights

Metoclopramide (Definition)

Reglan (metoclopramide) improves GI motility and is also ...Read more