Doctor insights on:
How Reliable Is The Ca 125 Test
Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?
Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read moreSee 1 more doctor answer
Ca125 is also known as Cancer antigen 125. Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more
CA-125: Cancer antigen 125 (ca-125) is a protein found on the surface of many ovarian cancer cells. It also can be found in other cancers and in small amounts in normal tissue. A ca-125 test measures the amount of this protein in the blood and can be used as a tumor marker. ...Read moreSee 1 more doctor answer
Screening? No: Ca 125 is not a screening test. It can be elevated for reasons other than cancer. It should be used for follow up of certain cancers ie ovarian cancer. Even then, it is done periodically as part of surveillance strategy. Also used to help the clinician decide if a patient who is on chemotherapy is responding or not & some oncologists obtain them per 'cycle' of chemotherapy i.e. Every 3-4 wks. ...Read more
Yes and No: Ca-125 is a test for follow-up after diagnosis and with the treatment of ovarian cancer. It is elevated in many other diseases.The test should not be used for a fishing expedition because it would be misleading and concerning for a patient like you. Why was the test done in the first place? Do you have cancer? In any case a 25 level could be normal? What was the normal range.In the lab? ...Read more
Can a hemorhaggic, endometrioma or fibroid cause high level on the ca-125 test? I am 27 y/o with a level of 190. I have a 10cm and 4cm cyst on ovaries
Measures a protein: The ca-125 test is a blood test that detects a protein in the blood that is produced by malignant ovarian cells. It is used to help determine if an ovarian cancer patient has had a relapse, or to help differentiate a cyst found by sonogram or ct. The most important point: it should never be used as a yearly screening test, and should not be requested by patients as a screening test. ...Read more
Not very.: Ca 125 is touted as a screening tool for ov ca but is elevated in only 50% of those with early stage disease. Approx 1% of normals have a high ca 125. Since ovarian cancer is relatively uncommon, the ability of a positive test to predict ca is about 3%. There is general consensus that ca 125 is not a good screening tool for average risk females. Consider ca 125 for those with high risk. ...Read more
Other conditions too: Ca25 test can be positive in many conditions pregnancy endometriosis uterine fibroids pancreatitis liver disease normal menstruation other malignancies like lung, breast.Pacreas and GI tract cysts of the ovaries so here you have it it is not a specific test for ovarian cancer, thogh it may be positive as well. ...Read more
CA-125: This marker is elevated significantly at this value. It's greatest specificity for ovarian cancer is in post-menopausal women, but a variety of things that irritate the lining of the abdomen and even chest, can elevate it mildly. So things like appendicitis, endometriosis, and even diverticulosis can also result in high levels. But, getting checked out for what is behind this is a good idea. ...Read more
- Talk to a doctor live online for free
- Is the hida scan a reliable test?
- How accurate is the finger prick cholesterol test?
- Ca 125 blood test how long for results
- Ask a doctor a question free online
- How accurate is the pregnancy test?
- How accurate is the dettol pregnancy test?
- How accurate is the mri test for a mcl tear?
- What makes the ca 125 test results to go up?
- Talk to an oncologist and hematologist online for free