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Doctor insights on: How Quickly Does Zoloft Start To Become Effective

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How quickly does Zoloft (sertraline) start to become effective?

How quickly does Zoloft (sertraline) start to become effective?

Zoloft (sertraline) onset: According to research studies, about 75% of patients will improve in the first four weeks, but it may take 4 to 6 weeks for the other 25% to improve with antidepressant treatment. Also, it is important a person takes an adequate dose, for some, this may be as much as 150-200 mgs per day. I would go to a dr. Who would see me every few weeks until i was better. Good luck. ...Read more

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Dr. Donald Jacobson
1,039 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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How long do the side effects of Zoloft (sertraline) last? How long till the medicine is effective and I start noticing a difference in myself?

How long do the side effects of Zoloft (sertraline) last? How long till the medicine is effective and I start noticing a difference in myself?

Sertraline effects: some Pts notice mild improvement in mood or anxiety within days of starting an SSRI (doses are adjusted daily in hosp). pts will need to be on a therapeutic dose for up to 8 weeks to see full benefits of the med. Pts also differ with respect to SEs. Most Pts have only self limited or rather tolerable SEs (like dry mouth). Rarely, more serious SEs occur. Talk to your doc about your risks/benefits ...Read more

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I was on Zoloft (sertraline) for 8 Month & quit gradullay, Now I rebound and Dr. Prescribed it again, I read on Internet that this may be not effective, I'm afraid?

I was on Zoloft (sertraline) for 8 Month & quit gradullay, Now I rebound and Dr. Prescribed it again, I read on Internet that this may be not effective, I'm afraid?

Restarting Zoloft (sertraline): Your doctor is right to restart Zoloft (sertraline). If it helped you previously, it should be as effective now. Be aware it may take several weeks to adjust the dose so you feel the benefit. Assume you take this for anxiety or depression. I hope this helps. ...Read more

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Is Zoloft (sertraline) better or safer or more effective than luvox ?

Is Zoloft (sertraline) better or safer or more effective than luvox ?

FDA indications: Luvox (Fluvoxamine) is approved by the FDA for the treatment of obsessive compulsive disorder. However, it has been used off-label by some to treat major depressive disorder, PTSD, panic disorder and social anxiety disorder. Sertraline (Zoloft/ Lustral) is an SSRI which is FDA approved for treatment of major depressive disorder, panic disorder, social anxiety disorder, post traumatic disorder ...Read more

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I have anxiety.My Zoloft (sertraline) dose was raised from 50(was fine for 2 years)to100(fine for 6mos and now 150 anxiety back.Have you seen this amount effective?

I have anxiety.My Zoloft (sertraline) dose was raised from 50(was fine for 2 years)to100(fine for 6mos and now 150 anxiety back.Have you seen this amount effective?

Yes: Doses of antidepressants like zoloft (sertraline) needed for symptom control can vary from person to person, and from time to time in their lives. If your prescribing doctor isn't a psychiatrist, it might be time to consult one. Also, working in psychotherapy can help you discover what drives your anxiety, and learn how to modulate it. The book "the mindful way through anxiety" can be very helpful too. ...Read more

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Is Zoloft (sertraline) the most effective medication for anxiety and depression?

One of several: Zoloft (sertraline) is an effective drug for treating anxiety and depression. Other drugs in its class (ssris) are also effective for these conditions. The most effective drug is the one you tolerate which works. ...Read more

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Is Effexor (venlafaxine) more effective for panic disorder than Zoloft?

Is Effexor (venlafaxine) more effective for panic disorder than Zoloft?

Different strokes...: The polls of patients say slightly more prefer Zoloft (sertraline) for panic, but it's a very unique fit. Neither was initially for that - they're antidepressants. That said it's often effective for panic and much, more combined w/ CBT therapy. Discuss w/ Dr. Don't do it yourself! ...Read more

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How effective is sertraline (Zoloft) for treating obsessive compulsive disorder (OCD)?

How effective is sertraline (Zoloft) for treating obsessive compulsive disorder (OCD)?

It's effective: Studies indicate SSRIs including sertraline, fluoxetine (Prozac), citalopram (Celexa) and paroxetine (Paxil) can reduce OCD symptoms by 40-60%. SSRIs may also be used in combination with two empirically validated psychotherapies, Exposure plus Response Prevention and Cognitive Therapy. Ask your doctor for more information about your options. ...Read more

Dr. Alan Ali
991 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more