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Doctor insights on: How Quickly Does Benadryl Start To Work

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How quickly does Benadryl (diphenhydramine) start to work?

How quickly does Benadryl (diphenhydramine) start to work?

About 30 minutes: Lasts in the body for about 4-6 hours and then it needs to be redosed. ...Read more

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Dr. John Chiu
1,037 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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How fast should Benadryl (diphenhydramine) work?

How fast should Benadryl (diphenhydramine) work?

15 to 60 minutes: It start working within 15 to 60 minutes of ingestion. ...Read more

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Would Benadryl (diphenhydramine) work for my mild sa?

Would Benadryl (diphenhydramine) work for my mild sa?

?sa: I am going to assume "sa" is seasonal allergies. So, yes, Benadryl (diphenhydramine) would work for these, but is certainly not the optimal answer. Benadryl (diphenhydramine) tends to be sedating and also needs to be taken 4 times a day for optimal effect. If you are having to take doses that often to keep symptoms under control, should consider alternative treatment for allergies. If "sa" not allergies, please resubmit question. ...Read more

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Does Benadryl (diphenhydramine) work for anxiety?

Does Benadryl (diphenhydramine) work for anxiety?

Time For DroolSchool: We here on the ranch call it"Benadrool"because it can shlog you out.So yes sometimes it can work for calming down. But too much turns it into Bena-DryMouthBlurredVisionKnockedOut-Dryl.So just take one capsule(25mg)or at most 50mg. It's not usually prescribed for this.There are other medications specifically for anxiety. But Benadryl (diphenhydramine) is a non-prescription medication and usually safe at proper doses ...Read more

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Does Benadryl (diphenhydramine) work for jock itch?

Does Benadryl (diphenhydramine) work for jock itch?

Possibly: Benedryl is an antihistamine which helps itching associated with hypersensitivity reactions such as allergies, bug bites, etc. You may find some transient relief of itching caused by fungal infections, but the ultimate treatment would be that of cure (i.e. topical antifungal cream/powder/spray). ...Read more

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Do Ambien and Benadryl (diphenhydramine) work the same way?

Do Ambien and Benadryl (diphenhydramine) work the same way?

Not at all: Ambien is a prescription only sleep aid which works directly on the brain to reduce electrical activity thereby causing sleep. Benadryl (diphenhydramine) which is used for treatment of allergies causes sleep as a side effect by working on different than Ambien brain receptors called H1. Consult with a physician if you need to take sleep aids on a regular basis. ...Read more

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Which goes to work faster? Claritin or Benadryl (diphenhydramine)

Which goes to work faster? Claritin or Benadryl (diphenhydramine)

About the same speed: Unless Benadryl (diphenhydramine) is injected, either starts to work between 1-2 hrs. ...Read more

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Can allegra work the same as benadryl (diphenhydramine)?

Can allegra work the same as benadryl (diphenhydramine)?

Antihistamines: Both are antihistamines. Benadryl (diphenhydramine) works for a maximum of 6 hours, Allegra works for 24. Allegra is non drowsy but Benadryl (diphenhydramine) is very sedating. ...Read more

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Does Claritin work better than benadryl (diphenhydramine)?

Not necessarily: Claritin is non-sedating at 10 mg and is a once daily medication. It has an onset of action approximately 30 minutes after taking. Benadryl (diphenhydramine) tends to work more quickly but lasts only 4-6 hours and can be sedating. ...Read more

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I used Benadryl (diphenhydramine) and it dried up my rash in two nights. How did it work?

I used Benadryl (diphenhydramine) and it dried up my rash in two nights. How did it work?

By itself: The rash would have dried up in the same time with or without benadryl (diphenhydramine). The only way Benadryl (diphenhydramine) might have helped would be its effect on itching thus cutting your edge to scratch the rash ...Read more

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Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more