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Doctor insights on: How Painful Is An Endometrial Biopsy Procedure

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Is endometrial biopsy a very painful procedure? Was told once I have a narrower cervix. Stories online are causing me much panic & sleepiness nights.

Is endometrial biopsy a very painful procedure?  Was told once I have a narrower cervix. Stories online are causing me much panic & sleepiness nights.

Relax: Please relax! Most women do fine with endometrial biopsy. The doctor inserts a very thin 3mm straw like pipe into your uterus to obtain some tissue. It is true that you might have pain and discomfort and cramps, but if you relax and breathe the actual insertion part takes only a minute or two. Take 800mg ibuprofen and 1000mg acetaminophen an hour before procedure if not allergic to them. ...Read more

Dr. Dariush Saghafi
2 doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more


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How is endometrial biopsy done? Can this procedure confirm presence of abnormal cells or a surgery/operation is required to check for abnormal cells?

How is endometrial biopsy done? Can this procedure confirm presence of abnormal cells or a surgery/operation is required to check for abnormal cells?

Uterine sample: Usually an endometrial biopsy is completed in the office by inserting a small catheter/tube through your cervix and into the uterus. This takes a sample of tissue from the lining of the uterus. It can evaluate the presence of normal or abnormal cells in the uterus. A surgical procedure (D&C) may be necessary if unable to do an office biopsy. ...Read more

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[contd from q re: 60 year old to have endometrial biopsy] I have never had symptoms of uterine problems (bleeding, cramps, pain, etc). Why is this procedure being performed? My last pap was normal.

Why would: U let your doc do a procedure without asking him or her why ? I do not know any doc who would do that without a reason ! in my pts the reason i would do it and i would tell them the reason before hand , would be post menopausal bleeding, or too thick endometrium on a pelvic ultrasound, or endometrial cells seen on a pap, but my pt would know why and have the choice to refuse the bx. ...Read more

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55 yow, history of complex partial seizures, postmenopausal, endometrial biopsy neg, day hosp. hysteroscope D&C scheduled, could this procedure trigger a seizure?

55 yow, history of complex partial seizures, postmenopausal, endometrial biopsy neg, day hosp. hysteroscope D&C scheduled, could this procedure trigger a seizure?

Unlikely: But, if your complex partial seizures are not well controlled, and your medications are placed on hold for the procedure, then you do have increased risks. Maybe receive your meds that day via intravenous route. ...Read more

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How painful is an endometrial biopsy? I've read stories about women passing out, going into shock, etc. Any truth to those claims? I'm so scared

Discomfort: Different people react differently to the discomfort of dilatation of the cervix that is needed to pass the instrument through the canal. The biopsy per se should not be that painful. Express your concern to your doctor to ensure you have adequate pain medication and if needed, be under moderate sedation. ...Read more

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Had endometrial biopsy 2 days ago and found it very painful wig no painkillers. Been booked for a novasure while I'm awake. Will this hurt too?

Had endometrial biopsy 2 days ago and found it very painful wig no painkillers. Been booked for a novasure while I'm awake. Will this hurt too?

Other options: Most people find an endometrial ablation slightly uncomfortable. If you found it very painful then you may not be a good candidate for an in office Novasure due to a low pain tolerance. Novasure is more uncomfortable than a biopsy. You may want to ask to have it done under general anesthesia in a hospital. ...Read more

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My doctor attempted to do an endometrial biopsy and had to stop because it was very painful. What are the alternative options I have to to get this d?

My doctor attempted to do an endometrial biopsy and had to stop because it was very painful.  What are the alternative options I have to to get this d?

Sonogram or sedation: A pelvic sonogram performed by a certified skilled sonographer or a saline sonohysterogram may help decide if an endometrial sampling is really necessary. If your endometrium is "thickened", an office procedure under sedation or paracervical anesthesia is an "alternative option"; otherwise you may need a dilatation of your cervix in an OR or ambulatory surgical unit served by an anesthesiologist ...Read more

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With painful periods w/large clots, the ob gyn did a endometrial biopsy. After 4 days, i'm still spotting/bleeding w/pain after walking little. Ideas?

With painful periods w/large clots, the ob gyn did a endometrial biopsy. After 4 days, i'm still spotting/bleeding w/pain after walking little. Ideas?

Unsure: It may be related to the biopsy, or from whatever is causing your heavy bleeding. If you are having fever, you should call your doctor soon. If no fever, some Ibuprofen or tylenol (acetaminophen) if you are not allergic should help. ...Read more

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Dr. Deepali Kashyap
155 doctors shared insights

Endometrial Biopsy (Definition)

Endometrial biopsy: a common procedure for sampling the inner lining of ...Read more