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Doctor insights on: How Often Is Hemolytic Disease Of The Newborn Fatal

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How often is hemolytic disease of the newborn fatal?

How often is hemolytic disease of the newborn fatal?

Depends on form: Decades ago when i started rh hemolytic disease was often fatal during pregnancy & problamatic in newborns. Surviving infants often needed many exchange transfusions & had worrisome futures. Then a treatment called Rhogam came along & has ended that nightmare. In 26 yrs, I have transfused 1-2 ABO babies primarily for late stage anemia but had no fatalities. Rh disease is a problem without rx. ...Read more

Dr. William Singer
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Neonatal (Definition)

The term neonatal is generally used to describe events that occur with an infant within the first 30 days after birth.Some practitioners are looser with the definition & extend the ...Read more


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How can hemolytic disease of the newborn occur?

How can hemolytic disease of the newborn occur?

Antibodies: Mom has an antibody against an antigen that baby has on the red cells acquired from dad. The antibody crosses the placenta. Rhogam has done wonders to prevent antibodies against rh/d from causing the devastating illness that used to be common. ...Read more

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What is the treatment for hemolytic disease of newborn?

What is the treatment for hemolytic disease of newborn?

Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read more

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How common is death from hemolytic-uremic syndrome?

How common is  death from hemolytic-uremic syndrome?

Depends on type: Children with enterotoxic hus die 5% or less. With atypical hus the death rate is higher with chronic recurrent episodes. ...Read more

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How can hemolytic disease be prevented in a newborn?

How can hemolytic disease be prevented in a newborn?

ABO hemolysis: Hemolysis in newborns due to ABO incompatibility is not preventable, but is manageable under the care of an experienced pediatrician or neonatologist. For this reason, newborns from mothers with type O blood type or who are Rh- will be screened closely for this condition, as early recognition and intervention is key to successful recovery. ...Read more

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Can you tell me the three classifications of hemolytic disease of the newborn?

Can you clarify?: The three most common blood group systems to cause hemolytic disease of the newborn are rh (usually d antigen, sometimes others), ABO (more common but less troublesome) and kell, though others can do it as well. Was this your question? If not, please write back. ...Read more

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What is the most common cause of neonatal sepsis?

What is the most common cause of neonatal sepsis?

Changing: Currently that is changing, probably due to preventive measures for group b streptococcus (gbs), which has been the leading cause for decades. Escherchia coli has taken over as the leading cause in premature babies while gbs still leads in full term neonates. ...Read more

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What is the cause of death for people with cystic fibrosis?

What is the cause of death for people with cystic fibrosis?

Respiratiry failure: Usually progressive respiratory embarrassment from the primary disease. Some pts die of refractory infection as a consequence of cystic fibrosis. Malabsorption from cystic fibrosis may also contribute to mortality. ...Read more

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How dangerous is the disease bacterial meningitis in a baby?

How dangerous is the disease bacterial meningitis in a baby?

Potentially fatal: Although we have seen a great reduction of the bacterial meningitis frequency in the us since the introduction of the hib vaccine in the '90's, bacterial meningitis does still occur and may be devastating.It is more common in unvaccinated populations & includes several agents.The case fatality & complication rate varies with the germ and how quickly treatment is started. ...Read more

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Which is the cause of polycythemia vera in infants of diabetic mothers?

Which is the cause of polycythemia vera in infants of diabetic mothers?

Polycythemia: Because blood sugar may be elevated in diabetic mothers, the blood cells become more viscous and can cause polycythemia in the newborn. Also if the cord isn't cut for three minutes, polycythemia may result. ...Read more

Emily Lu Dr. Lu
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How common is the inherited persistence of fetal hemoglobin?

Emily Lu Dr. Lu
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How common is  the inherited persistence of fetal hemoglobin?

Difficult to measure: This is difficult to measure because in most people with inherited persistence of fetal hemoglobin are entirely asymptomatic. However, population studies have shown that about 10% of the population has been seen to have some persistence of fetal hemoglobin but in varying levels (from 0.8% of cells containing the fetal hemoglobin up to about 10% fetal hemoglobin levels). ...Read more

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What diseases is the umbilical cord of a newborn baby used to treat?

What diseases is the umbilical cord of a newborn baby used to treat?

Blood cell disorders: It is the blood obtained from the cord, not the cord itself, that is being used to treat disease. Early, primitive cells, called stem cells, are used to treat many disorders of the blood, including aplastic and other anemias, leukemias, certain immunologic diseases, and even some metabolic disorders. Ongoing research includes non-blood diseases, such as stroke, diabetes, and even heart attacks. ...Read more

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Is there a genetic test for hemolytic disease of the newborn?

Is there a genetic test for hemolytic disease of the newborn?

Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more

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What is the cause of thrombocytopenia in malaria patients?

What is the cause of thrombocytopenia in malaria patients?

Enlarged spleen: The spleen is enlarged in patients with malaria and an enlarged spleen form any cause can destroy more platelets and cause thrombocytopenia. ...Read more

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Which type of genetic liver disease can cause the same symptoms as shaken baby syndrom?

Which type of genetic liver disease can cause the same symptoms as shaken baby syndrom?

None: I have never heard of a liver disease, which gives the same symptoms as "shaken baby" syndrome. ...Read more

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What is the cause of thrombocytopenia in most malaria patients?

Enlarged spleen: An enlarged spleen, due to any cause can cause excessive destruction of platelets. Malaria is generally associated with an enlarged spleen. ...Read more

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What exactly is heart disease and why is it the leading cause of death in America?

What exactly is heart disease and why is it the leading cause of death in America?

CAD plus: Heart disease is a broad category of any condition that affects the heart. The most common condition and the condition that is the leading cause of death is coronary artery disease. This is a condition in which the blood vessels on the surface of the heart which bring blood to the heart muscle develop blockages. When these coronary arteries become blocked the result can be a heart attack. ...Read more

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What is the treatment of child known case of G6bd deficiency diagnosed with kawasaki disease?

What is the treatment of child  known case of G6bd deficiency diagnosed with kawasaki disease?

Complex: Children with Kawasaki disease are treated with IVIG (immunoglobin)and initially, high dose aspirin.Having G6PD deficiency complicates things a bit because high dose aspirin therapy can cause a severe hemolytic anemia. Still, high dose aspirin therapy would more than likely be initiated, but intensely close monitoring for the development of hemolysis would be employed.Stopping the Rx stops hemolys ...Read more

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In cirrhosis does the presence of ascites always indicate decompensation and is this considered a serious complication and stage of the disease?

In cirrhosis does the presence of ascites always indicate decompensation and is this considered a serious complication and stage of the disease?

It is concerning: Ascites- buildup of fluid in the abdominal cavity- can be a sign of serious decompensation in the liver function. This is usually seen in the later stages of liver failure. If this is seen you should let your doctor know right away. This is associated with decreased survival. However if the cause of the liver damage is found early-& treated this can delay progression. Cirrhosis can't be undone. ...Read more

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