Doctor insights on:
How Often Is Hemolytic Disease Of The Newborn Fatal
Depends on form: Decades ago when i started rh hemolytic disease was often fatal during pregnancy & problamatic in newborns. Surviving infants often needed many exchange transfusions & had worrisome futures. Then a treatment called Rhogam came along & has ended that nightmare. In 26 yrs, I have transfused 1-2 ABO babies primarily for late stage anemia but had no fatalities. Rh disease is a problem without rx. ...Read more
Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read moreSee 1 more doctor answer
ABO hemolysis: Hemolysis in newborns due to ABO incompatibility is not preventable, but is manageable under the care of an experienced pediatrician or neonatologist. For this reason, newborns from mothers with type O blood type or who are Rh- will be screened closely for this condition, as early recognition and intervention is key to successful recovery. ...Read more
Potentially fatal: Although we have seen a great reduction of the bacterial meningitis frequency in the us since the introduction of the hib vaccine in the '90's, bacterial meningitis does still occur and may be devastating.It is more common in unvaccinated populations & includes several agents.The case fatality & complication rate varies with the germ and how quickly treatment is started. ...Read more
Difficult to measure: This is difficult to measure because in most people with inherited persistence of fetal hemoglobin are entirely asymptomatic. However, population studies have shown that about 10% of the population has been seen to have some persistence of fetal hemoglobin but in varying levels (from 0.8% of cells containing the fetal hemoglobin up to about 10% fetal hemoglobin levels). ...Read moreSee 1 more doctor answer
Blood cell disorders: It is the blood obtained from the cord, not the cord itself, that is being used to treat disease. Early, primitive cells, called stem cells, are used to treat many disorders of the blood, including aplastic and other anemias, leukemias, certain immunologic diseases, and even some metabolic disorders. Ongoing research includes non-blood diseases, such as stroke, diabetes, and even heart attacks. ...Read more
Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more
None: I have never heard of a liver disease, which gives the same symptoms as "shaken baby" syndrome. ...Read more
CAD plus: Heart disease is a broad category of any condition that affects the heart. The most common condition and the condition that is the leading cause of death is coronary artery disease. This is a condition in which the blood vessels on the surface of the heart which bring blood to the heart muscle develop blockages. When these coronary arteries become blocked the result can be a heart attack. ...Read moreSee 3 more doctor answers
Complex: Children with Kawasaki disease are treated with IVIG (immunoglobin)and initially, high dose aspirin.Having G6PD deficiency complicates things a bit because high dose aspirin therapy can cause a severe hemolytic anemia. Still, high dose aspirin therapy would more than likely be initiated, but intensely close monitoring for the development of hemolysis would be employed.Stopping the Rx stops hemolys ...Read more
In cirrhosis does the presence of ascites always indicate decompensation and is this considered a serious complication and stage of the disease?
It is concerning: Ascites- buildup of fluid in the abdominal cavity- can be a sign of serious decompensation in the liver function. This is usually seen in the later stages of liver failure. If this is seen you should let your doctor know right away. This is associated with decreased survival. However if the cause of the liver damage is found early-& treated this can delay progression. Cirrhosis can't be undone. ...Read moreSee 1 more doctor answer
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