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How Noticeable Is The Salty Skin That People Get With Cystic Fibrosis
Depends on Severity: This would depend on the severity of the disease state in the individual, but by and large, it's enough of a difference from "normal" sweat to make one take notice. Clinically, the sweat chloride level is measured twice to make the diagnosis of cystic fibrosis (cf). The cutoff level to make the diagnosis of CF is 60 milliequivalents per liter of sweat chloride. ...Read moreSee 1 more doctor answer
Cystic fibrosis is a genetic disorder involving lungs & digestive tract, causing recurrent lung infections due to thick inspissated mucus & poor growth in majority of patients due to malabsorption. Treatment involves inhaled respiratory therapies to prevent lung disease & pancreatic enzymes to enable absorption of nutrients. Average life expectancy is near 40 years, ...Read more
Not a reliable sign: Salty taste on kissing is one of the features of cystic fibrosis (CF) due to excess salt loss in sweat of CF patients. The chloride content of sweat is used as a diagnostic test for confirming the diagnosis of cf, but tasting the saltiness of skin is not reliable by itself. If there is a concern about cf, please contact your nearest CF center for an evaluation & sweat test. ...Read more
Depends on ethnicity: CF is a genetic condition inherited from carrier parent. Carrier frequency depends on the ethnic background . 1/25 caucasians have one copy of normal, one copy of a mutated CF gene. Both genes have to be mutated to have cf. Hispanic carrier frequency 1/50, africanam 1/70 , asian 1/90. 1/5000 babies are born with cf, this may be decreasing, since pregnent females are now screened for CF ...Read more
Chloride channel...: The genetic defect that causes cystic fibrosis (CF) interferes with the body’s ability to move salt in and out of cells. The salt that cannot be absorbed is excreted through the skin by the sweat glands, resulting in salty sweat. Sometimes, there may even be visible salt deposits on the skin. Salt excretion by the sweat glands is the basis of the most common test used to diagnose cf. ...Read more
No: You are born with cystic fibrosis, you don't "get" it later in life. It may not be diagnosed right away depending on the type and severity of symptoms. For example, a newborn with an intestinal blockage would be picked up quickly, but an older child or even an adult who presented with mostly sinus symptoms might not get diagnosed until later. ...Read moreSee 1 more doctor answer
Equal: More than 10 million americans are unknowing, symptomless carriers of the defective cystic fibrosis gene. In order to develop cf, an individual must inherit a defective gene from each parent. Since the CF gene is not on a sex chromosome (x or y), males and females are equally affected. ...Read more
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