Doctor insights on:
How Noticable Is The Salty Skin On A Person With Cystic Fibrosis
Not a reliable sign: Salty taste on kissing is one of the features of cystic fibrosis (CF) due to excess salt loss in sweat of CF patients. The chloride content of sweat is used as a diagnostic test for confirming the diagnosis of cf, but tasting the saltiness of skin is not reliable by itself. If there is a concern about cf, please contact your nearest CF center for an evaluation & sweat test. ...Read more
Depends on Severity: This would depend on the severity of the disease state in the individual, but by and large, it's enough of a difference from "normal" sweat to make one take notice. Clinically, the sweat chloride level is measured twice to make the diagnosis of cystic fibrosis (cf). The cutoff level to make the diagnosis of CF is 60 milliequivalents per liter of sweat chloride. ...Read moreSee 1 more doctor answer
Chloride channel...: The genetic defect that causes cystic fibrosis (CF) interferes with the body’s ability to move salt in and out of cells. The salt that cannot be absorbed is excreted through the skin by the sweat glands, resulting in salty sweat. Sometimes, there may even be visible salt deposits on the skin. Salt excretion by the sweat glands is the basis of the most common test used to diagnose cf. ...Read more
Varies: Not everyone has a similar experience post lung transplant. In general, respiratory symptoms and breathing, overall improve, and people are able to do activities they were not able to do before as easily. Not all respiratory symptoms go away. Various medications are required and close follow up is mandatory. Survival after lung transplantation is ~ 50% at 5 years. ...Read moreSee 1 more doctor answer
Pancreatic insuffic: The pancrease (pancrelipase) is the organ that (among other things) secretes enzymes that help the body absorb fat. In CF the pancrease (pancrelipase) can become clogged and fail to do this... So the patient needs to take enzymes orally. Additionally, when the lungs are injured enough, cfers will start having a lack of appetite as well, the cause of this is less clear. ...Read moreSee 2 more doctor answers
Is it possible for a person to have a "minor" form of cystic fibrosis so-to-speak? And if yes, how would it manifest?
Yes: I would rather use a term "mild" or "atypical" instead of minor form of cystic fibrosis. Cystic fibrosis is caused by mutation involving cftr gene, and there are a few hundred different mutations. Atypical or mild form of CF manifest at a later age than in infancy as often seen in classic form, and mild in symptoms. ...Read moreSee 1 more doctor answer
Extra loss: Cystic fibrosis is caused by a genetic mutation of cftr protein that moves chloride ions out of cells in respiratory tract, but into the cells in sweat gland ducts. Since cftr protein is not functional in CF pts, excess chloride gets secreted in their sweat, which causes the sweat to have higher salt concentration. That is why a sweat test measuring chloride is used as a diagnostic test for cf. ...Read more
What happens if there is an intrapulmonary shunt or the person has cystic fibrosis, can they survive on a ventilator?
Yes: Shunts and CF do not preclude survival on a ventilator. It may be more difficult to clear secretions from CF on ventilator but can be done ...Read more
Varies: Newborns can present with bowel obstruction from lthickened meconium , early stool, from lack of normal enzymes.Sometimes bowel atresia and twisted bowel in utero are other manifestations. In child, respiratory symptoms may result with over aeration and asthmatic symptoms from mucus plugging in lungs. Malabsorption, fatty liver, and anemia in early childhood. Some mild forms do not show until later. ...Read more
As a carrier: Genetic carrier testing: more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more
Poor growth/GI: In some children, 1st sign of CF is poor growth with child being small for age. This may be subtle enough that child continues to follow a growth curve on the growth chart, but in the lower percentiles until growth flattens out. Others have loose greasy stools as 1st sign. Frequent "bronchitis"/"sinus infections" that are thought to be just that until someone asks if that's just too many. ...Read more
Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US.A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications.Emotional & phys. development depend on severity, time in hospital, complications.Morb. & mort.factors afect emotional,cognitive behavior. ...Read more
Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read moreSee 1 more doctor answer
No: You are born with cystic fibrosis, you don't "get" it later in life. It may not be diagnosed right away depending on the type and severity of symptoms. For example, a newborn with an intestinal blockage would be picked up quickly, but an older child or even an adult who presented with mostly sinus symptoms might not get diagnosed until later. ...Read moreSee 1 more doctor answer
One gene bad: The cftr gene codes for (has information for your body about) a sodium-chloride transporter on your cell membranes. If you have two bad copies you have cf, if you have one, you are a carrier. As many as 1 in 25 caucasian adults in the us has this mutation. If you are planning on having children, talk to your spouse about genetic counseling, unless your spouse is of asian or african descent. ...Read more
- Talk to a doctor live online for free
- How noticeable is the salty skin that people get with cystic fibrosis?
- How noticeable is salty skin with cystic?
- Why do people with cystic fibrosis have salty skin?
- Ask a doctor a question free online
- Cystic fibrosis skin problems
- Why do people with cystic fibrosis have unusually salty sweat?
- How to prevent cystic fibrosis?
- How serious is cystic fibrosis?
- Talk to a pediatrician online