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Doctor insights on: How Much Of The Population Is Affected By Muscular Dystrophy

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How much of the population is affected by muscular dystrophy?

How much of the population is affected by muscular dystrophy?

Unknown: The incidence is underestimated. Limb girdle dystrophy is actually under diagnosed, although still pretty rare. Always need muscle biopsy to rule out acquired polymyositis. ...Read more

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Dr. Kathryn Mosher
141 doctors shared insights

Muscular Dystrophy (Definition)

Muscular dystrophy includes a number of disorders which are associated primarily with abnormalities of the architecture of the cells, often causing changes in size and function (weakness). These disorders are typically inherited, and recognized early in life, although there are of course exceptions to this. Prognosis is based on the type of MD and expression ...Read more


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Why is the glycosylation of dystroglycan important for its function as in the case with duchennes muscular dystrophy?

Muscle unstable: Dystrophin is an important components of the skeleton of the muscle fiber that helps keep the membrane stable and the membrane proteins "anchored" in the correct place in the cells that allows to perform their normal function. When this is absent such as in duchenne, the muscle fibers degenerate. The sarcoglycans are other components that are linked to dystrophin and have relatively similar role. ...Read more

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How many americans are affected by duchenne muscular dystrophy? Is this common?

Approximately 14,000: Duchenne muscular dystrophy is a recessive x-linked form of muscular dystrophy, affecting around 1 in 3, 600 boys, which results in muscle degeneration. Approximately 14, 000 americans suffer from dmd. ...Read more

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What is the link between immobility and the complications of duchenne muscular dystrophy?

It's progressive: The most common forms of muscular dystrophy are progressive. Immobility in general is related to muscle atrophy independent of disease. Patients with muscular dystrophy who stay active retain independence longer than those who do not, and some medications and surgeries can assist in this goal. ...Read more

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How often does duchenne muscular dystophy occur in the american population?

How often does duchenne muscular dystophy occur in the american population?

Common: One boy in 3500 is born to develop duchenne's; it's uncommon in girls. Since the boys do not live as long as other people, around 1 child in 7000 has duchennes but it's much less common among adults. Becker's, the mild version, is about as common and most patients make it well into middle age. ...Read more

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How does immobility of the muscular and skeletal systems occur?

How does immobility of the muscular and skeletal systems occur?

Several ways.: Injury, disease (stroke), treatment (cast), severe mental illness like depression or catatonic states. What specifically do you want to know? ...Read more

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What is the biological cause of muscular dystrophy?

What is the biological cause of muscular dystrophy?

Muscular dystrophies: are a group of inherited neuromuscular disorders. Of the 9 major types & > 100 related disorders, each is caused by a specific mutant gene or genes. Some are inherited in an X-linked recessive pattern from a carrier mother; others are autosomal dominant, meaning each child of an affected parent has a 50% chance of inheriting it. Please specify the type to know the specific genetic defect. ...Read more

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What is the difference in MS and muscular dystrophy?

What is the difference in MS and muscular dystrophy?

Striking differences: Muscular dystrophy usually starts in childhood or adolescence, less commonly later in life. It is a hereditary progressive condition, causing problems with weakness in skeletal muscles, and occasionally cardiac muscles, with abnormal muscle enzymes. MS is an inflammatory autoimmune condition, affecting brain, spinal cord, and eyes, with relapses and remissions. MRI lesions can confirm. ...Read more

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How is leptospirosis spread and what part of the body is most affected by the disease?

How is leptospirosis spread and what part of the body is most affected by the disease?

Animal urine: You get leptospirosis from contact with the urine of animals, especially rodents. This may occur with the ingestion of contaminated water, food or soil. The disease starts with a fever, headache, and other flu-like symptoms. After recovering from those symptoms, you can then go on to develop meningitis, kidney failure, and liver damage with jaundice. ...Read more

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What race is mostly affected by dwarfism?

Dwarfism: Good wikipedia question and go to uptodate. I also recommend you learn to us pubmed.com to help with your research. ...Read more

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What is the frequency of brain cancer, is it heredity or genetic?

What is the frequency of brain cancer, is it heredity or genetic?

It is neither: Common, nor hereditary. There seems to be damage to genes, as in most cancers, and some forecast response to therapy (loss of chromosome 1). The dread glioblastoma, the far end of the histologic spectrum, has had very little progress therapeutically. Despite its local resistance, chemo approachs encourage many, but surgery and radiotherapy seem stalled. ...Read more

Dr. Alan Ali Dr. Ali
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What is the population affected by angelman syndrome?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
What is the population affected by angelman syndrome?

Angelman s.: Newborns with genetic abnormality involving chromosome #15q ( partial deletion of short piece of that chromosome). ...Read more

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How high is the percentage of obesity is caused by genes?

How high is the percentage of obesity is caused by genes?

Uncertain: Many researchers agree that genes may predispose some people to excess weight gain, although the exact relationship between genetics & obesity is unclear. Other inherited factors related to obesity could determine metabolic rates & how the body processes food. Studies on obesity genetics continue to indicate that heredity can contribute to obesity. ...Read more

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Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

Why cystic fibrosis only affects the caucasian population and how the disease may have originated?

not true: Cystic fibrosis is a metabolic disorder more common in caucasions by present in many populations.The incidence is 1/3500 caucasion, 1/17, 000 african american, 1/80, 000 native american. It arises in mutations in the cftr gene that regulates cellular transport of chloride.There are in excess of 700 known mutations recorded but most common is the delta 508. ...Read more

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Tell me about muscular dystrophy DMD. The test like CPK to identify the problem measured in which unit and is there different type of CPK test?

Muscular dystrophy: Muscular dystrophy is a genetic disorder affecting the muscles. There are different types with different modes of inheritance, age of onset and severity. The CK (or CPK), creatinine kinase are usually elevated in any one. There are different isoenzymes for CK yet it is the total CK that is measured and important in muscular dystrophy. The final diagnosis is made by genetic testing or other tests ...Read more

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If acetylcholinesterase is not present to remove acetylcholine, the muscle is in contraction. What is the name of the disorder/disease?

If acetylcholinesterase is not present to remove acetylcholine, the muscle is in contraction. What is the name of the disorder/disease?

Acetylcholinesterase: is always present. Acetylcholine doesn't just cause muscle contraction; it's essential in the CNS as well. You can't have absence in one place & presence in the other. Our bodies don't work that way. An absence of acetylcholinesterase is not compatible with life. ...Read more