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Doctor insights on: How Much Does Taking Weekly Humira Injections Lower My Immune System

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How much does taking weekly humira (adalimumab) injections lower my immune system?

How much does taking weekly humira (adalimumab) injections lower my immune system?

Not definitive: It lowers resistance, but unclear how much. Essential is avoiding infectious exposure. Avoid individuals who have had live vaccines - for 30 days after vaccination. ...Read more

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Dr. Robert Lowe
169 doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more


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I have uc. I take humira (adalimumab) bi weekly but still have active colitis. Wants me to do weekly humira (adalimumab). How much more does this suppress your immune system?

I have uc. I take humira (adalimumab) bi weekly but still have active colitis. Wants me to do weekly humira (adalimumab). How much more does this suppress your immune system?

It does suppress it: In general, when someone takes humira (adalimumab) more frequently, their immune system will theoretically be more affected. That being said, no more tests will be needed. Also, one should assess the risk and the benefit of any intervention, because every intervention carries risk with it. Humira (adalimumab) here is trying to postpone the need for surgery. ...Read more

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How much does humira (adalimumab) compromise my immune system?

How much does humira (adalimumab) compromise my immune system?

No simple answer: Some physicians use t cell subsets to measure immune impairment but there are many other tests. It is actually quite hard to quantify easily. ...Read more

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Is there an immune system build up after discontinuing humira (adalimumab)?

Humira (adalimumab): The body makes tnf- Alpha as one of the proteins involved in systemic inflammation. When any tnf blocker is stopped inflammation will usually increase and the levels of many cytokines that are involved in inflammation increase as the systemic inflammation increases but tnf is only one protein that increases with increases in inflammation. There is not a build up. ...Read more

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Immune system build up after discontinuing humira, (adalimumab) can you tell me about this?

Humira (adalimumab) Clearance: It takes about 5-6 x the "half life" for the body to metabolize / excrete a medication from the body. The "half life" of Humira (adalimumab) is 10-20 days. The shortest time period it would take for Humira (adalimumab) to be cleared from your body would be 5x10 or 50 days (almost 2 months) and the longest would be 6x20 or 120 days (4 months). Probably after 3 months your immune system wouldn't see the effects of Humira (adalimumab) ...Read more

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Is it true that taking the combination of prednisone and Humira (adalimumab) for 6 months is not safe and suppresses the immune system completely?

MD supervision: Is mandatory while using those strong medications, counseling is important too, which I'm sure happened, yes steroids and biologicals suppress the immun system, but not permanently ...Read more

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Trying to boost my immune system.Can i take echinacea or astragalus while on humira (adalimumab) for as?

Humira (adalimumab) and herbs: Yes, however, there is no scientific data that these herbs will do anything. A healthy diet is the best way to boost your immune system. ...Read more

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What would happen if one took methotrexate injections weekly and their immune system was not overactive? Would they feel sick or have side effects?

Yes: In many patients yes in many patients know it is a liver toxin which causes fibrosis of the liver with long-term use . This has to be monitored all during the drug usage every six months. ...Read more

Dr. Robert Lowe
184 doctors shared insights

Humira (Definition)

Humira is an arthritis therapy which is a ...Read more