Doctor insights on:
How Much Does Taking Weekly Humira Injections Lower My Immune System
I have uc. I take humira (adalimumab) bi weekly but still have active colitis. Wants me to do weekly humira (adalimumab). How much more does this suppress your immune system?
It does suppress it: In general, when someone takes humira (adalimumab) more frequently, their immune system will theoretically be more affected. That being said, no more tests will be needed. Also, one should assess the risk and the benefit of any intervention, because every intervention carries risk with it. Humira (adalimumab) here is trying to postpone the need for surgery. ...Read more
Humira (adalimumab): The body makes tnf- Alpha as one of the proteins involved in systemic inflammation. When any tnf blocker is stopped inflammation will usually increase and the levels of many cytokines that are involved in inflammation increase as the systemic inflammation increases but tnf is only one protein that increases with increases in inflammation. There is not a build up. ...Read moreSee 1 more doctor answer
Humira (adalimumab) Clearance: It takes about 5-6 x the "half life" for the body to metabolize / excrete a medication from the body. The "half life" of Humira (adalimumab) is 10-20 days. The shortest time period it would take for Humira (adalimumab) to be cleared from your body would be 5x10 or 50 days (almost 2 months) and the longest would be 6x20 or 120 days (4 months). Probably after 3 months your immune system wouldn't see the effects of Humira (adalimumab) ...Read more
Should I take something to help boost my immune system while taking Humira (adalimumab)? Have genital warts (HPV) that appeared recently. Immune system issue?
What would happen if one took methotrexate injections weekly and their immune system was not overactive? Would they feel sick or have side effects?
Yes: In many patients yes in many patients know it is a liver toxin which causes fibrosis of the liver with long-term use . This has to be monitored all during the drug usage every six months. ...Read more
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