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Doctor insights on: How Much Does Humira Compromise My Immune System

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How much does humira (adalimumab) compromise my immune system?

How much does humira (adalimumab) compromise my immune system?

No simple answer: Some physicians use t cell subsets to measure immune impairment but there are many other tests. It is actually quite hard to quantify easily. ...Read more

Dr. Robert Lowe
177 Doctors shared insights

Adalimumab (Definition)

Adalimumab is an arthritis therapy which is a ...Read more


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How much does taking weekly humira (adalimumab) injections lower my immune system?

How much does taking weekly humira (adalimumab) injections lower my immune system?

Not definitive: It lowers resistance, but unclear how much. Essential is avoiding infectious exposure. Avoid individuals who have had live vaccines - for 30 days after vaccination. ...Read more

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Is there an immune system build up after discontinuing humira (adalimumab)?

Humira (adalimumab): The body makes tnf- Alpha as one of the proteins involved in systemic inflammation. When any tnf blocker is stopped inflammation will usually increase and the levels of many cytokines that are involved in inflammation increase as the systemic inflammation increases but tnf is only one protein that increases with increases in inflammation. There is not a build up. ...Read more

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Immune system build up after discontinuing humira, (adalimumab) can you tell me about this?

Immune system build up after discontinuing humira, (adalimumab) can you tell me about this?

Humira (adalimumab) Clearance: It takes about 5-6 x the "half life" for the body to metabolize / excrete a medication from the body. The "half life" of Humira (adalimumab) is 10-20 days. The shortest time period it would take for Humira (adalimumab) to be cleared from your body would be 5x10 or 50 days (almost 2 months) and the longest would be 6x20 or 120 days (4 months). Probably after 3 months your immune system wouldn't see the effects of Humira (adalimumab) ...Read more

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Trying to boost my immune system. Can I take echinacea or astragalus while on humira (adalimumab) for as?

Humira (adalimumab) and herbs: Yes, however, there is no scientific data that these herbs will do anything. A healthy diet is the best way to boost your immune system. ...Read more

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Is it true that taking the combination of prednisone and Humira (adalimumab) for 6 months is not safe and suppresses the immune system completely?

MD supervision: Is mandatory while using those strong medications, counseling is important too, which I'm sure happened, yes steroids and biologicals suppress the immun system, but not permanently ...Read more

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Can diabetes compromise my immune system?

Can diabetes compromise my immune system?

Glucose immune syst: When the blood sugar is high, white blood cells do not work as well to fight off infections. When the blood sugar is well controlled, the immune system generally works well in patients with diabetes. In diabetics with other problems (renal failure, neuropathy, poor circulation, etc) then there can be compounding of problems leading to immune compromise. ...Read more

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Can kidney cyst compromise my immune system?

Can kidney cyst compromise my immune system?

No.: One person in four has a simple kidney cyst. Ignore it. I wish all the questions here were this easy! Thanks for writing. ...Read more

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Can having hypothroidism or taking zyrtec (cetirizine) daily compromise my immune system?

Yes and No: Not a lot. No. Zyrtec (cetirizine) can help the symptoms of a overreactive part of the system that we call allergy but does not influence the immune system. Hypothyroidism can in more severe cases realted to influences on other structures in the body. ...Read more

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Can a ppi compromise your immune system?

Technically no.: A ppi does not directly affect your immune system, but because of reduced stomach acidity you may have more bacteria able to survive in your upper GI tract. This could be important in the event you are intubated or aspirate your gastric contents. So... I guess your overall "system" may be less effective but it is not a result of an immune defect. ...Read more

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Can you tell me why an individual with a compromised immune system (for example, a person with aids) may be unable to?

Can you tell me why an individual with a compromised immune system (for example, a person with aids) may be unable to?

Suppressed immunity: THere are many reasons for a compromised immune system. This can cause increased susceptibility to infections of various kinds. As such, one must take extra care to avoid things that will increase infection risks, such as direct contact with someone who is ill. As well, some live vaccines may be contraindicated, and certain types of travel may be ill-advised. ...Read more

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Will having a compromised immune system and generally being overall unhealthy affect MGUS that I've been diagnosed with several years ago?

Will having a compromised immune system and generally being overall unhealthy affect MGUS that I've been diagnosed with several years ago?

Difficult to answer: Only about 1% of MGUS progress to more sever lesion each year. So the risk is low that you will get multiple myeloma. However, you must follow your doctor's advise for follow-up tests to detect any changes. ...Read more

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Seeing as sepsis is an overreaction by the immune system, are immune compromised individuals capable of getting sepsis?

Seeing as sepsis is an overreaction by the immune system, are immune compromised individuals capable of getting sepsis?

Yes and more severe: Sepsis is more frequent and generally more dangerous in people with immune compromise. You are over-interpreting the science involved. It is true that some manifestations of sepsis result from immune system overreaction. But the main problem is unrestrained growth of bacteria, which is a problem in many kinds of immune deficiency. ...Read more

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Can diabetes compromise the immune system?

Can diabetes compromise the immune system?

Yes: Poorly controlled diabetes can suppress your immune system causing poor wound healing and lesser ability to fight infection. ...Read more

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How does being overweight compromise the immune system and why?

How does being overweight compromise the immune system and why?

Theoretical, unproved: See the following abstract from the national institutes of health: http://www. Ncbi. Nlm. Nih. Gov/pubmed/8281221 it's very technical-just pay attention to the first & last sentences. In summary: obesity may reversibly impair a certain type of white cell (lymphocytes) but clearly, considering that almost half the usa is obese, the effect is minor if it occurs at all. ...Read more

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What are the health risks of AIDS, aside from a compromised immune system?

What are the health risks of AIDS, aside from a compromised immune system?

Don't need more: Than immunodeficiency, however malignancy remains another health risk after opportunistic infections in AIDS patients, but again stemming from the fact that immune surveillance is compromised too, wish everybody wellness ...Read more

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Can having multiple sexual partners compromise your immune system?

Think twice: If a sexual partner is infected with hiv, you would be at risk for contracting the infection leading to acquired immune deficiency (aids). ...Read more

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I Had mono 30 years ago, now my daughter has it, and my immune system is compromised, What are the chances that I can get it again?

I Had mono 30 years ago, now my daughter has it, and my immune system is compromised, What are the chances that I can get it again?

Depends: Usually, once you have had an infection, your immune system remembers that and you have a lower risk of getting that infection again. Mono sometimes can recur despite this. The real question is what type of immune system compromise you have. ...Read more

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What are the long-term effects of chemo and immunosuppressants? (long after you're cured). Will your immune system always remain more compromised?

What are the long-term effects of chemo and immunosuppressants? (long after you're cured). Will your immune system always remain more compromised?

Not true: The immune system is minimally compromised during chemo but the effects are temporary. As soon as the blood counts recover (4 weeks after last chemo), the immune system is practically back to normal. Total body irradiation as done for allogeneic bone marrow transplantation is the only therapy that has longer lasting immunosuppression. ...Read more

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Is immune system compromised when w/d from fentanyl? In supervised w/d and I have caught a nasty flu.

It can be: The stress response to withdrawal from opiates can indeed alter your immune system function via stress hormones such as cortisol. However, the flu you caught may have been caught even if you were not withdrawing. Your symptoms may seem worse because the aches and pains feel worse when you are in withdrawal. ...Read more

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Can staph/strep be difficult to cure if my immune system is compromised?

Can staph/strep be difficult to cure if my immune system is compromised?

Depends: On which part of the immune system is compromised, if it is a neutrophil problem, cells responsible for eating up the staph organisms, yes you can a problem eradicating the organism on your own or even with oral antibiotics, you might need a strong antibiotic injection, and at times through intravenous infusion, at any rate keep a close follow up with your doctor ...Read more

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I have a compromised immune system, am I am I more susceptible for staph infections?

It depends...: ...On how your immune system is compromised. If you take medication to suppress your immune system (e.g. Prednisone), then you may be at greater risk. Some immune deficiencies may increase risk for staph, while others may increase risk for different infections (not caused by staph). You should discuss your concerns with a clinical immunologist. ...Read more

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I have a compromised immune system due to meds I'm on and quite often get infects such as sinus, yeast and MRSA what can I do to help prevent these?

I have a compromised immune system due to meds I'm on and quite often get infects such as sinus, yeast and MRSA what can I do to help prevent these?

Preventive measures: People w meds or health problems affecting immunity can take measures to reduce infections (CHECK W DOC 1st!)MRSA can be carried in the nose;if testing +, can be treated. Avoiding contact w infected fluids + washing/disinfecting surfaces can help. Folds of skin should be kept dry to prevent skin yeast infections. For vaginal, eating yogurt may help. Sinuses:Controlling allergies&using Neti Pot can help. ...Read more

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What is the incidence of shingles in var. Vaccinated children? 18 month old with shingles outbreak should I be worried about compromised immune system

What is the incidence of shingles in var. Vaccinated children? 18 month old with shingles outbreak should I be worried about compromised immune system

Lifetime incidence: The lifetime incidence of shingles is relatively less with the vaccine than with wild chickenpox, but occurs with both. I have seen it in a 1yo in a kid with an otherwise normal immune system. As with any issue, surveillance of an individuals response to a variety of infections over many years can reveal an acquired immune problem (not present or evident in childhood). ...Read more

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Once the HPV virus cleared up by the immune system will be only dormant? After years or so if the immunity compromised the virus will be active again?

Once the HPV virus cleared up by the immune system will be only dormant? After years or so if the immunity compromised the virus will be active again?

Dormant: HPV comes from a family of viruses that can remain dormant in your system for your lifetime. It can possibly re-activate, and you can shed virus without knowing it. However, for most this is just a possibility, not an expected outcome. ...Read more

Dr. Robert Lowe
193 Doctors shared insights

Humira (Definition)

Humira is an arthritis therapy which is a ...Read more