Doctor insights on: How much does humira compromise my immune system
Humira (adalimumab): The body makes tnf- Alpha as one of the proteins involved in systemic inflammation. When any tnf blocker is stopped inflammation will usually increase and the levels of many cytokines that are involved in inflammation increase as the systemic inflammation increases but tnf is only one protein that increases with increases in inflammation. There is not a build up. ...Read moreSee 1 more doctor answer
Humira (adalimumab) Clearance: It takes about 5-6 x the "half life" for the body to metabolize / excrete a medication from the body. The "half life" of Humira (adalimumab) is 10-20 days. The shortest time period it would take for Humira (adalimumab) to be cleared from your body would be 5x10 or 50 days (almost 2 months) and the longest would be 6x20 or 120 days (4 months). Probably after 3 months your immune system wouldn't see the effects of Humira (adalimumab) ...Read more
I have uc. I take humira (adalimumab) bi weekly but still have active colitis. Wants me to do weekly humira (adalimumab). How much more does this suppress your immune system?
Somewhat more!: But weekly doses are sometimes needed!Get a more detailed answer ›
Should I take something to help boost my immune system while taking Humira (adalimumab)? Have genital warts (HPV) that appeared recently. Immune system issue?
Glucose immune syst: When the blood sugar is high, white blood cells do not work as well to fight off infections. When the blood sugar is well controlled, the immune system generally works well in patients with diabetes. In diabetics with other problems (renal failure, neuropathy, poor circulation, etc) then there can be compounding of problems leading to immune compromise. ...Read more
Technically no.: A ppi does not directly affect your immune system, but because of reduced stomach acidity you may have more bacteria able to survive in your upper GI tract. This could be important in the event you are intubated or aspirate your gastric contents. So... I guess your overall "system" may be less effective but it is not a result of an immune defect. ...Read more
Can you tell me why an individual with a compromised immune system (for example, a person with aids) may be unable to?
Suppressed immunity: THere are many reasons for a compromised immune system. This can cause increased susceptibility to infections of various kinds. As such, one must take extra care to avoid things that will increase infection risks, such as direct contact with someone who is ill. As well, some live vaccines may be contraindicated, and certain types of travel may be ill-advised. ...Read more
Will having a compromised immune system and generally being overall unhealthy affect MGUS that I've been diagnosed with several years ago?
Seeing as sepsis is an overreaction by the immune system, are immune compromised individuals capable of getting sepsis?
Yes and more severe: Sepsis is more frequent and generally more dangerous in people with immune compromise. You are over-interpreting the science involved. It is true that some manifestations of sepsis result from immune system overreaction. But the main problem is unrestrained growth of bacteria, which is a problem in many kinds of immune deficiency. ...Read more
Theoretical, unproved: See the following abstract from the national institutes of health: http://www. Ncbi. Nlm. Nih. Gov/pubmed/8281221 it's very technical-just pay attention to the first & last sentences. In summary: obesity may reversibly impair a certain type of white cell (lymphocytes) but clearly, considering that almost half the usa is obese, the effect is minor if it occurs at all. ...Read more
No: It's mostly your genes and is basically a curiosity. ...Read more
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