Doctor insights on:
How Much Does Humira Compromise My Immune System
No simple answer: Some physicians use t cell subsets to measure immune impairment but there are many other tests. It is actually quite hard to quantify easily. ...Read more
Not definitive: It lowers resistance, but unclear how much. Essential is avoiding infectious exposure. Avoid individuals who have had live vaccines - for 30 days after vaccination. ...Read more
Humira (adalimumab): The body makes tnf- Alpha as one of the proteins involved in systemic inflammation. When any tnf blocker is stopped inflammation will usually increase and the levels of many cytokines that are involved in inflammation increase as the systemic inflammation increases but tnf is only one protein that increases with increases in inflammation. There is not a build up. ...Read more
Humira (adalimumab) Clearance: It takes about 5-6 x the "half life" for the body to metabolize / excrete a medication from the body. The "half life" of Humira (adalimumab) is 10-20 days. The shortest time period it would take for Humira (adalimumab) to be cleared from your body would be 5x10 or 50 days (almost 2 months) and the longest would be 6x20 or 120 days (4 months). Probably after 3 months your immune system wouldn't see the effects of Humira (adalimumab) ...Read more
I have uc. I take humira (adalimumab) bi weekly but still have active colitis. Wants me to do weekly humira (adalimumab). How much more does this suppress your immune system?
Somewhat more!: But weekly doses are sometimes needed!Get a more detailed answer ›
Should I take something to help boost my immune system while taking Humira (adalimumab)? Have genital warts (HPV) that appeared recently. Immune system issue?
Glucose immune syst: When the blood sugar is high, white blood cells do not work as well to fight off infections. When the blood sugar is well controlled, the immune system generally works well in patients with diabetes. In diabetics with other problems (renal failure, neuropathy, poor circulation, etc) then there can be compounding of problems leading to immune compromise. ...Read more
Technically no.: A ppi does not directly affect your immune system, but because of reduced stomach acidity you may have more bacteria able to survive in your upper GI tract. This could be important in the event you are intubated or aspirate your gastric contents. So... I guess your overall "system" may be less effective but it is not a result of an immune defect. ...Read more
Can you tell me why an individual with a compromised immune system (for example, a person with aids) may be unable to?
Suppressed immunity: THere are many reasons for a compromised immune system. This can cause increased susceptibility to infections of various kinds. As such, one must take extra care to avoid things that will increase infection risks, such as direct contact with someone who is ill. As well, some live vaccines may be contraindicated, and certain types of travel may be ill-advised. ...Read more
Will having a compromised immune system and generally being overall unhealthy affect MGUS that I've been diagnosed with several years ago?
Seeing as sepsis is an overreaction by the immune system, are immune compromised individuals capable of getting sepsis?
Yes and more severe: Sepsis is more frequent and generally more dangerous in people with immune compromise. You are over-interpreting the science involved. It is true that some manifestations of sepsis result from immune system overreaction. But the main problem is unrestrained growth of bacteria, which is a problem in many kinds of immune deficiency. ...Read more
Theoretical, unproved: See the following abstract from the national institutes of health: http://www. Ncbi. Nlm. Nih. Gov/pubmed/8281221 it's very technical-just pay attention to the first & last sentences. In summary: obesity may reversibly impair a certain type of white cell (lymphocytes) but clearly, considering that almost half the usa is obese, the effect is minor if it occurs at all. ...Read more
No: It's mostly your genes and is basically a curiosity. ...Read more
I Had mono 30 years ago, now my daughter has it, and my immune system is compromised, What are the chances that I can get it again?
What are the long-term effects of chemo and immunosuppressants? (long after you're cured). Will your immune system always remain more compromised?
Not true: The immune system is minimally compromised during chemo but the effects are temporary. As soon as the blood counts recover (4 weeks after last chemo), the immune system is practically back to normal. Total body irradiation as done for allogeneic bone marrow transplantation is the only therapy that has longer lasting immunosuppression. ...Read more
Is immune system compromised when w/d from fentanyl? In supervised w/d and I have caught a nasty flu.
It can be: The stress response to withdrawal from opiates can indeed alter your immune system function via stress hormones such as cortisol. However, the flu you caught may have been caught even if you were not withdrawing. Your symptoms may seem worse because the aches and pains feel worse when you are in withdrawal. ...Read more
My question is, how can a sick person that has a compromised or week immune system be given perscription drugs but we can't give them to a well person?
Rx drugs: We need more information to answer your question. What specific drugs are you talking about? ...Read more
Depends: On which part of the immune system is compromised, if it is a neutrophil problem, cells responsible for eating up the staph organisms, yes you can a problem eradicating the organism on your own or even with oral antibiotics, you might need a strong antibiotic injection, and at times through intravenous infusion, at any rate keep a close follow up with your doctor ...Read more
It depends...: ...On how your immune system is compromised. If you take medication to suppress your immune system (e.g. Prednisone), then you may be at greater risk. Some immune deficiencies may increase risk for staph, while others may increase risk for different infections (not caused by staph). You should discuss your concerns with a clinical immunologist. ...Read more
I have a compromised immune system due to meds I'm on and quite often get infects such as sinus, yeast and MRSA what can I do to help prevent these?
Preventive measures: People w meds or health problems affecting immunity can take measures to reduce infections (CHECK W DOC 1st!)MRSA can be carried in the nose;if testing +, can be treated. Avoiding contact w infected fluids + washing/disinfecting surfaces can help. Folds of skin should be kept dry to prevent skin yeast infections. For vaginal, eating yogurt may help. Sinuses:Controlling allergies&using Neti Pot can help. ...Read more
What is the incidence of shingles in var. Vaccinated children? 18 month old with shingles outbreak should I be worried about compromised immune system
Lifetime incidence: The lifetime incidence of shingles is relatively less with the vaccine than with wild chickenpox, but occurs with both. I have seen it in a 1yo in a kid with an otherwise normal immune system. As with any issue, surveillance of an individuals response to a variety of infections over many years can reveal an acquired immune problem (not present or evident in childhood). ...Read more
Once the HPV virus cleared up by the immune system will be only dormant? After years or so if the immunity compromised the virus will be active again?
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