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Doctor insights on: How Many Benadryl Can I Take For An Allergic Reaction

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Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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How much Benadryl (diphenhydramine) can I take for an allergic reaction.?

How much Benadryl (diphenhydramine) can I take for an allergic reaction.?

50 mg: Is usually a goo dose. Often, 25 mg will do. Benadryl (diphenhydramine) can be taken every 4 - 6 hours. The most common side effect is drowsiness. ...Read more

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How many 25mg Benadryl (diphenhydramine) are safe to take for an allergic reaction?

How many 25mg Benadryl (diphenhydramine) are safe to take for an allergic reaction?

Just Answered: You can take 2 x 25 mg tab. Every 4 hours/day with max. Dose of 400 mg (adult dose). Don't drive because drowsiness is one of the side effects. Others are: tachycardia, dry mouth, hypotension, paradoxical excitement, etc. ...Read more

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I have had an allergic reaction to Bactrim, I currently have hives from head to toe, literally. What dose of benadryl can I take?

I have had an allergic reaction to Bactrim, I currently have hives from head to toe, literally. What dose of benadryl can I take?

Depends: Benadryl is sedating and interacts with alcohol and other sedating meds. 25mg is usually a good starting point. Always read and follow the directions provided with any otc medication. Also recommend a long-acting medication such as cetirizine for sustained effect when treating new hives) Notify the treating physician and, if hives occur in other circumstances, see an Allergist. ...Read more

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I'm having n allergic reaction to ambian can I take benadryl (diphenhydramine) to help?

Benadryl (diphenhydramine): Benadryl (diphenhydramine) will help with itching and rash from an allergic reaction. An individual with lip or tongue swelling, or any sensation of difficulty breathing should be seen by a doctor right away. ...Read more

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How much Benadryl (diphenhydramine) can you take for allergic reaction?

How much Benadryl (diphenhydramine) can you take for allergic reaction?

BENADRYL (diphenhydramine) DOSE:: Up to 50 mg each dose every 4 hours as needed. Maximum dose not more than 400 mg in a day.
Adverse events: drowsiness, hypotension, increased heart rate, paradoxical excitement, dry mouth, thickened bronchial secretions, etc. ...Read more

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Other than benadryl, (diphenhydramine) what else can I take to stop an allergic reaction from getting worst?

Other than benadryl, (diphenhydramine) what else can I take to stop an allergic reaction from getting worst?

See your doctor/ER: In the interim keep taking the benadryl (diphenhydramine) as directed, if an allergic reaction is getting worse, you'd better be seen and evaluated, good luck ...Read more

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I am having an allergic reaction to salmon, should I take benadryl?

I am having an allergic reaction to salmon, should I take benadryl?

If mild hives or...: If a food reaction is merely itching, nausea, or some hives, a person can take antihistamines (like Benadryl) to decrease the reaction. Hives are due to release of histamine, commonly related to allergy to foods, medicines, viruses, molds, animals, pollens, etc... Some people release histamine and get hives when exposed to cold temperatures, cold water, sunshine, stressful situations, etc... ...Read more

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I'm allergic to Benadryl (diphenhydramine) and im having an allergic reaction what can I take?

I'm allergic to Benadryl (diphenhydramine) and im having an allergic reaction what can I take?

Benadryl (diphenhydramine) allergy: Kind of rare, but present, can try other OTC antihistamines as cetirizine, loratadine or fexofenadine, might still get sedated but to a lesser extent than diphenhydramine (benadryl) so be careful when you drive or operate machinery ...Read more

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Is it okay to take Benadryl (diphenhydramine) with aller tec (by kirklands) for an allergic reaction?

Is it okay to take Benadryl (diphenhydramine) with aller tec (by kirklands) for an allergic reaction?

Not necessary: Allertec contains Cetirizine (zyrtec) which is a very good new generation antihistamine. Benadryl (diphenhydramine) is an older antihistamine that doesn't last as long and has more side effects. Likely the main issue with using both together at usual doses would be drowsiness, fatigue and delayed reaction time. ...Read more

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I had allergic reaction & took 2 benadryl (diphenhydramine). Within 15 mins, I threw up. I'm worried I threw up the med before it worked. How soon can I take more?

Seek medical help: I'm not sure what kind of allergic reaction you are having but throwing up can be part of a serious allergic reaction if accomanied with other symptoms. (anaphylaxis) seek medical help. ...Read more

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Can I take mucinex D and benadryl (diphenhydramine)? I have taken mucinex D for a combination of a cold and allergies but just had an allergic reaction to a food.

Can I take mucinex D and benadryl (diphenhydramine)? I have taken mucinex D for a combination of a cold and allergies but just had an allergic reaction to a food.

Yes, but. . .: If any tongue or lip swelling, or difficulty breathing/swallowing, call 911 or local emergency services. Need to avoid allergen & carry EpiPen (epinephrine). www. Drugs. Com Interactions Checker says there's no interaction btwn Mucinex D (guaifenesin & pseudoephedrine) & Benadryl (diphenhydramine). However, only antihistamine like latter is useful for allergies. Former is combo of expectorant & decongestant. ...Read more

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Benadryl (diphenhydramine) tabs take about 1 hour to start working to treat my allergic reaction (rash) Would Benadryl (diphenhydramine) IM be a faster alternative? Can I obtain an RX?

Benadryl (diphenhydramine) tabs take about 1 hour to start working to treat my allergic reaction (rash) Would Benadryl (diphenhydramine) IM be a faster alternative? Can I obtain an RX?

Depends: Benadryl (diphenhydramine) may help hives but not a rash which has lasted more than 24 hrs. IM Benadryl (diphenhydramine) gives you perhaps a 30-minute head start vs oral = not worth the cost or hassle. If you have throat swelling, you may need adrenaline and an allergy consult since this can be life-threatening. ...Read more

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Is there a difference between taking Benadryl vs reactine? I had an anaphylactic allergic reaction a few weeks ago and was recommended to take 25-50 m

Both: Are anti-histamines. Benadryl however produced drowsiness whereas the newer anti-histamines (eg "Reactine") are less likely to do that! For anaphylaxis I would stick to BENADRYL. (Plus an EP-PEN!!!!!)
It has a long history of safety/effectiveness
Hope this helps
Dr Z ...Read more

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1st severe allergic reaction 2 something last night. Given steroids & benadryl (diphenhydramine). Reaction returned today. How long do I need to take meds 2 rid this?

1st severe allergic reaction 2 something last night. Given steroids & benadryl (diphenhydramine). Reaction returned today. How long do I need to take meds 2 rid this?

Depends: It depends on exposures such as foods, medications, environmental, etc. If this resulted in swelling of the tongue or throat, a blood allergy test is in order. Additionally, an EpiPen (epinephrine) should be available to you at all times. Continue steroid until the prescriptions complete. You may want to continue the antihistamine longer however. See your physician for testing. ...Read more

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I had a severe allergic reaction to ciprofloxacin (only took 2 pills) and have been on steroids&benadryl for 5 days. How long will it take to clear?

About a week.: You should be able to get off the Benadryl (diphenhydramine) now if your not having any chest pain, shortness of breath, difficulty swallowing or swelling of face and neck. Take the steroids a couple more days. Make sure this is ok with your doctor. If you have severe return of your previous symptoms, go to the ER. ...Read more

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If I get severe irritability when I take benadryl (diphenhydramine) is it still ok to take occasionally when having an allergic reaction? Safe to take?

If I get severe irritability when I take benadryl (diphenhydramine) is it still ok to take occasionally when having an allergic reaction? Safe to take?

Appears safe.: If irritability is your only side effect it is apparently not a physical threat. Are you able to tolerate the irritability without threatening your livelihood, family, or significant relationships? There are other antihistamines. ...Read more

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Never took trymadol til yesterday when prescribed wake up itching I got some Benadryl (diphenhydramine) is itching allergic reaction doctor said was k take still?

Never took trymadol til yesterday when prescribed wake up itching I got some Benadryl (diphenhydramine) is itching allergic reaction doctor said was k take still?

Drug reaction: Itching could be considered a drug reaction. It may become worse the next time you take the medication. You may even get a rash. I csn't predict how your body is going to react. It does not make sense to use another drug, which may be sedating to counteract the side effect of another drug. Ask your doctor to switch you to something else or use OTC Meds if you can control your pain. ...Read more

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In the event of a hives-only, but still troubling, allergic reaction, what can someone allergic to Benadryl (diphenhydramine) take? Don't wanna use an epipen for hives.

In the event of a hives-only, but still troubling, allergic reaction, what can someone allergic to Benadryl (diphenhydramine) take? Don't wanna use an epipen for hives.

Hives: Depending on the extent of your hives, you may wish to seek medical help. You can go to a walk in clinic or emergency room. I doubt your hives are from benadryl (diphenhydramine). Whatever prompted you to take Benadryl (diphenhydramine) may have been the cause of your hives. ...Read more

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I had an allergic reaction (bugbite) and was given steroids and zyrtec. Can I take Benadryl (diphenhydramine) for itch before bed if I take both of those in the morning?

I had an allergic reaction (bugbite) and was given steroids and zyrtec. Can I take Benadryl (diphenhydramine) for itch before bed if I take both of those in the morning?

Yes: Benadryl (diphenhydramine) is one of the best anti-itch antihistamines, and can be taken together with zyrtec and steroids. The only caution is that as you take more antihistamine, there is an increased likelihood of drowsiness. This obviously isn't a problem at bedtime, and will help you sleep through the itchiness, but be very careful about taking extra antihistamines if you'll be driving or operating machinery. ...Read more

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Would it be wise to take Benadryl (diphenhydramine) 50mg before CT scan with contrast just incase of allergic reaction?

Would it be wise to take Benadryl (diphenhydramine) 50mg before CT scan with contrast just incase of allergic reaction?

Talk to radiologist: But it will not likely help to prevent a true anaphylactic reaction by itself although it will not hurt either. ...Read more

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Is it safe to take Benadryl (diphenhydramine) and Zyrtec together? I was put on Zyrtec for an allergic reaction with steroids for swelling and it's keeping me awake.

Is it safe to take Benadryl (diphenhydramine) and Zyrtec together? I was put on Zyrtec for an allergic reaction with steroids for swelling and it's keeping me awake.

Zyrtec (cetirizine) not the cause: It's unlikely that Zyrtec is keeping you awake. If anything, it usually causes drowsiness. You can take one dose of Benadryl (diphenhydramine) with Zyrtec, although it's not usually recommended as it may cause dizziness or excess sedation. ...Read more

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I had an allergic reaction to makeup. My eyes are red swollen and itchy. I have both benadryl (diphenhydramine) and claritin, which would be better to take?

I had an allergic reaction to makeup. My eyes are red swollen and itchy. I have both benadryl (diphenhydramine) and claritin, which would be better to take?

Contact dermatitis: Sounds like you are suffering from allergic contact dermatitis from makeup product. OTC antihistamines can help with itch but the best treatment for contact dermatitis is topical corticosteroid creams. Talk with your doctor and consider scheduling patch testing with an allergist to determine your sensitivities so you can avoid this reaction in the future. ...Read more

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Bug / insect bites with allergic reaction. Can I take hydrocortisone and Benadryl (diphenhydramine) to cure?

Bug / insect bites with allergic reaction. Can I take hydrocortisone and Benadryl (diphenhydramine) to cure?

INSECT BITE ALLERGY: It depends on the allergic reaction. If it is only itchy bumps, hc cream or other steroids plus Benadryl (diphenhydramine) intake will suffice. If the reaction is severe like anaphylactic shock or angioedema, you need Epipen shots or call 911. ...Read more

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I had an allergic reaction to bell peppers two days ago. Should I take Benadryl (diphenhydramine) for the residual swelling in my throat or stick with advil?

I had an allergic reaction to bell peppers two days ago. Should I take Benadryl (diphenhydramine) for the residual swelling in my throat or stick with advil?

As needed: Unfortunately, food reactions can persist for several days as the material proceeds through your digestive tract. If you tolerate Benadryl (diphenhydramine) ok you can certainly use it for several days. The advil is unlikely to influence allergic swelling. ...Read more

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I am taking prednisone for an allergic reaction to azithromycin. Can I take Benadryl (diphenhydramine) before I sleep? Will it help with this kind of allergic reaction?

I am taking prednisone for an allergic reaction to azithromycin. Can I take Benadryl (diphenhydramine) before I sleep? Will it help with this kind of allergic reaction?

No answer: You left out the information needed to answer. Benadryl (diphenhydramine) may help if you have hives. If you do, there are much better antihistamines. If you want a sleeping pill, use Benadryl (diphenhydramine). DO NOT TAKE BENADRYL (diphenhydramine) IF YOU DRIVE. It is dangerous to be sleepy and drive. If you have a rash, not hives, no antihistamine will make the slightest difference. ...Read more

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My boyfriend has itchy bumps on his hips, thighs and genital area. He takes 2 benadryl, (diphenhydramine) 4 Advil and b&e powder for his tooth ache. Allergic reaction maybe?

My boyfriend has itchy bumps on his hips, thighs and genital area. He takes 2 benadryl, (diphenhydramine) 4 Advil and b&e powder for his tooth ache. Allergic reaction maybe?

Yes, possibly: An allergy to advil (ibuprofen) can cause hives. If hives have another underlying cause then advil (ibuprofen) may exacerbate the underlying hive problem. Other possible causes of hives:

1. Allergies to pollens, mold, dust, food, drugs (like advil (ibuprofen)) and bee stings
2. Infections like hepatitis
3. Autoimmunity
4. Complement deficiency – acquired or hereditary
5. Vaculitis
6. Idiopathic – unknown cause. ...Read more

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I took 10 tablets of benadryl (diphenhydramine) not thinking because I had an allergic reaction. What should I do?

I took 10 tablets of benadryl (diphenhydramine) not thinking because I had an allergic reaction. What should I do?

Wait it out: Don't operate any machinery or vehicle. You may end up with dry mouth, constipation, and drowsiness but will not have life-threatening reactions. These effect should subside in about a day or so. If you took this many in a suicide attempt, call the suicide hotline immediately to get help. In the future, be sure not to exceed the recommend dose because you may not be as lucky the next time around. ...Read more

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Expert opinion please: could taking a Benadryl (diphenhydramine) before eating dairy stop my mild allergic reaction?

No advisable: You do not detail your "mild allergic reaction". If it is bloating and cramping and diarrhea, it is not an allergy but lactose intolerance and Benadryl (diphenhydramine) will have no effect, but lactaid pills will. If you are truly allergic as in hives, throat swelling shortness of breath, etc, I would avoid dairy at all cost. See an allergist to get tested. ...Read more

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I had a margarita around 8pm & an allergic reaction around 10:30pm. I took Benadryl @ 11:15pm not thinking about the margarita. Should I be worried?

I had a margarita around 8pm & an allergic reaction around 10:30pm. I took Benadryl @ 11:15pm not thinking about the margarita. Should I be worried?

Designated driver: Be sure you have a safe way back to your own bed. The additive forces of alcohol and an antihistamine would raise concerns about judgement and reaction time. Let someone else drive. ...Read more

Dr. John Chiu
1,044 Doctors shared insights

Allergic Reaction (Definition)

Sensitivities to substances, called allergens, that come into contact with the skin, nose, eyes, respiratory tract, and gastrointestinal tract. They can be inhaled into the ...Read more


Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more