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Doctor insights on: How Long Will Mono Show Up In Your Blood

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Can mono still show up on a blood test if your body has fought it all off? If so how long after can it

Can mono still show up on a blood test if your body has fought it all off?  If so how long after can it

May be life long: Mono is not a specific infection and similar symptoms can occur with more than one virus. EBV is the usual cause and once a person is infected, the virus stays in the body for the rest of the life and antibodies to EBV can be detected for years after the initial infection. The so call mono-spot test may become negative in a few months after infection. ...Read more

Dr. Michael Ein
760 doctors shared insights

Mono (Definition)

Infectious mononucleosis, also known as mono, is a contagious illness caused by the Epstein-Barr virus. Symptoms include fever, fatigue, sore throat, enlarged lymph nodes, and enlarged spleen. It is spread via saliva, hence its ...Read more


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How long after having mono will it show up in a blood test? And how long must you have it before it will show up

How long after having mono will it show up in a blood test? And how long must you have it before it will show up

It depends: It depends on the blood test, mono spot is helpful but not as sensitive as IgG and IgM titters. Igg will show if you have ever had it and IgM will show a recent or current infection. ...Read more

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It possible to be relapsing with mono and not show any obvious symptoms? Blood tests would be abnormal?

It possible to be relapsing with mono and not show any obvious symptoms? Blood tests would be abnormal?

Not likely relapse.: Infectious mononucleosis has 2 big causes. Cytomegalovirus (cmv), and epstein-barr virus (ebv). CMV has high fevers with chills, fatigue, and malaise. The main lab finding is peripheral lymphocytosis with over 10% atypical lymphocytes on blood smear. Ebv has pharyngitis and cervical lymphadenopathy. In both cases, infants may be asymptomatic or show mild diseaese, though CMV has side effects. ...Read more

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If you had mono already will it show up again on a blood test?

If you had mono already will it show up again on a blood test?

Yes: Depends on the blood test. There are antibody tests that determine if the mono is new or old, and if you have already had it in the past. ...Read more

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For how long after I have mono will my blood count of monocytes be elevated?

For how long after I have mono will my blood count of monocytes be elevated?

Not important: Is your diagnosis of infectious mono correct? Because high monocytes can represent a variety of other diseases also. If you had lab proven infectious mono, the monocytes stay up for 4-8 weeks but that is not important. If you are worried re infecting others, the + igm of ebv is what determines if you can infect someone else and that may stay up up to 18 months. ...Read more

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I was diagnosed with mono. Took a blood test recently and it had passed. Now I have an enlarged liver after the mono is gone, from what and how long?

I was diagnosed with mono. Took a blood test recently and it had passed. Now I have an enlarged liver after the mono is gone, from what and how long?

Can take a while: Mono is caused by 2 viruses (epstein-barr more often, cytomegalovirus-less common). Same presentation and clinical course. Usually about 2 weeks with fatigue, sore throat, swollen glands; either can cause liver inflammation (w/ or w/o enlargement), enlarged spleen. Can take up to 6 months for recovery. Follow up labs. No alcohol, eat right; no contact sports if enlarged liver/spleen, . ...Read more

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February I had bloodwork tested for Mono @ hospital. Do they do full blood counts? if I had a thyroid problem would it show on that test & notify me?

Hard to say: One mono test is quite specific and doesn't look for anything else.The lab is unlikely to do any test that is not ordered, so you must ask the personnel involved to see if anything else was done. ...Read more

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Would having mono 5 years ago cause a blood test to show possibility of autoimmune liver disease today?

Would having mono 5 years ago cause a blood test to show possibility of autoimmune liver disease today?

No: In fact, if you have labs suggesting autoimmune hepatitis, i would be very concerned and would be hammering away at my doctor for all the information i could get. It is possible that an old hepatitis (infectious mono, hepatitis a) may trigger autoimmune hepatitis -- the jury's out on this, but it's moot. Please comply with your diagnosis and if needed treatment, and enjoy a long healthy life. ...Read more