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Doctor insights on: How Long Will Mono Show Up In Your Blood

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Dr. Michael Ein
738 doctors shared insights

Mono (Definition)

Infectious mononucleosis, also known as mono, is a contagious illness caused by the Epstein-Barr virus. Symptoms include fever, fatigue, sore throat, enlarged lymph nodes, and enlarged spleen. It is spread via saliva, hence its ...Read more


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How long after having mono will it show up in a blood test? And how long must you have it before it will show up

How long after having mono will it show up in a blood test? And how long must you have it before it will show up

It depends: It depends on the blood test, mono spot is helpful but not as sensitive as IgG and IgM titters. Igg will show if you have ever had it and IgM will show a recent or current infection. ...Read more

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It possible to be relapsing with mono and not show any obvious symptoms? Blood tests would be abnormal?

It possible to be relapsing with mono and not show any obvious symptoms? Blood tests would be abnormal?

Not likely relapse.: Infectious mononucleosis has 2 big causes. Cytomegalovirus (cmv), and epstein-barr virus (ebv). CMV has high fevers with chills, fatigue, and malaise. The main lab finding is peripheral lymphocytosis with over 10% atypical lymphocytes on blood smear. Ebv has pharyngitis and cervical lymphadenopathy. In both cases, infants may be asymptomatic or show mild diseaese, though CMV has side effects. ...Read more

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If you had mono already will it show up again on a blood test?

If you had mono already will it show up again on a blood test?

Yes: Depends on the blood test. There are antibody tests that determine if the mono is new or old, and if you have already had it in the past. ...Read more

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For how long after I have mono will my blood count of monocytes be elevated?

For how long after I have mono will my blood count of monocytes be elevated?

Not important: Is your diagnosis of infectious mono correct? Because high monocytes can represent a variety of other diseases also. If you had lab proven infectious mono, the monocytes stay up for 4-8 weeks but that is not important. If you are worried re infecting others, the + igm of ebv is what determines if you can infect someone else and that may stay up up to 18 months. ...Read more

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I was diagnosed with mono. Took a blood test recently and it had passed. Now I have an enlarged liver after the mono is gone, from what and how long?

I was diagnosed with mono. Took a blood test recently and it had passed. Now I have an enlarged liver after the mono is gone, from what and how long?

Can take a while: Mono is caused by 2 viruses (epstein-barr more often, cytomegalovirus-less common). Same presentation and clinical course. Usually about 2 weeks with fatigue, sore throat, swollen glands; either can cause liver inflammation (w/ or w/o enlargement), enlarged spleen. Can take up to 6 months for recovery. Follow up labs. No alcohol, eat right; no contact sports if enlarged liver/spleen, . ...Read more

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February I had bloodwork tested for Mono @ hospital. Do they do full blood counts? if I had a thyroid problem would it show on that test & notify me?

Hard to say: One mono test is quite specific and doesn't look for anything else.The lab is unlikely to do any test that is not ordered, so you must ask the personnel involved to see if anything else was done. ...Read more

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Would having mono 5 years ago cause a blood test to show possibility of autoimmune liver disease today?

Would having mono 5 years ago cause a blood test to show possibility of autoimmune liver disease today?

No: In fact, if you have labs suggesting autoimmune hepatitis, i would be very concerned and would be hammering away at my doctor for all the information i could get. It is possible that an old hepatitis (infectious mono, hepatitis a) may trigger autoimmune hepatitis -- the jury's out on this, but it's moot. Please comply with your diagnosis and if needed treatment, and enjoy a long healthy life. ...Read more

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Sick for 2 weeks now. Throat so bad appeared to be mono (tests show it's not). Blood count normal. What's wrong?

Sick for 2 weeks now. Throat so bad appeared to be mono (tests show it's not). Blood count normal. What's wrong?

Ask your doctor: There are many causes of a sore throat. If you have been tested for mononucleosis you have seen a doctor, so go ask that doctor what he/she thinks you have. Perhaps you have sinusitis and allergies with post-nasal drip. Perhaps you have some other kind of infection. Only your doctor (or another who sees you) can figure this out. ...Read more

Dr. Jeff McFadden
719 doctors shared insights

Mononucleosis (Definition)

Glandular fever (infectious mononucleosis, or just "mono") is an illness caused by infection with the Epstein-Barr virus. The infection may feature fever, sore throat, fatigue, and swollen lymph ...Read more