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Doctor insights on: How Long Does Tamoxifen Take To Work

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How long does it take before you feel the side effects of tamoxifen?

How long does it take before you feel the side effects of tamoxifen?

You may not have: Tamoxifen is well tolerated by most, in estrogen receptor + tive breast cancers will prevent recurrences, immediate reaction can occur but rare, most of the other side effects like hot flashes, thrombo-venous problems, neurological problems may occur slowly but manageable.

Dr. Sean Canale
638 Doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


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Would nolvadex (tamoxifen) restore fertility in a man with hypogonadatropic hypogonadism caused by a prolactinoma? If so, how long would it take?

Would nolvadex (tamoxifen) restore fertility in a man with hypogonadatropic hypogonadism caused by a prolactinoma? If so, how long would it take?

Possibly: Nolvadex (tamoxifen) is not a common name. It may be an aromatase inhibitor - like anastrozole. Prolactinoma is best treated by removing it if large or tablets of bromocriptine / cabergoline. The urologist determines if is needed as well.

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I've been taking Adderall for 10 years (30 mg 2xday). What are the long-term effects of central nervous system stimulants? #nqlu I'm 57 & in addition to adderall, take Zoloft (50 mg), Armour Thyroid (90 mg), bystolic (10 mg), and tamoxifen (20 mg).

I've been taking Adderall for 10 years (30 mg 2xday). What are the long-term effects of central nervous system stimulants? #nqlu I'm 57 & in addition to adderall, take Zoloft (50 mg), Armour Thyroid (90 mg), bystolic (10 mg), and tamoxifen (20 mg).

Usually not many: Some doctors recommend having "holidays" from stimulants, for times when not having the best concentration and focus might not matter as much - like weekends, vacations etc. There is little or no evidence that long-term medicinal stimulants taken as prescribed cause any significant damage to the cns, although sleep disturbance/anxiety and hopelessness (depression) may be related. Talk to your doc.

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How does tamoxifen actually work?

How does tamoxifen actually work?

Blocks estrogen: Some breast cancer cells have receptors on them that bind to estrogen in order to grow. Tamoxifen acts as an "antagonist" and blocks estrogen from binding to these receptors on the cancer cells by binding to them first. With tamoxifen sitting in estrogen's place, the cancer cell can no longer grow.

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Is it safe to take tamoxifen every other day?

Is it safe to take tamoxifen every other day?

Speak to your doctor: This is not the usual regimen for tamoxifen. It is usually recommended for daily use and intake for the best effect. Was this recommended by your doctor? If so, you need to find out why this deviates from the standard recommendation. If you are making up your own regimen, please do not proceed until you speak with your physician.

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I'm supposed to take tamoxifen daily for 5 years. What happen if I missed a day, a week or more?

Aim for better adher: An occasional missed dose is not a big deal and would not compromise the efficacy of tamoxifen. But better adherence should be executed. One way to do this is to make it a habit to take your medicine same time everyday: it could be timed as the first thing or the last thing you do daily. Then it will become a habit.

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Is it ok to take risperdal along with tamoxifen?

Is it ok to take risperdal along with tamoxifen?

Risperdal/Tamoxifen: Although rare, there are reports of irregular heart rhythm from the combination. Advise talking to your doctor first.

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Is it okay to take Paxil (paroxetine) with tamoxifen?

Is it okay to take Paxil (paroxetine) with tamoxifen?

Caution advised: Hi. In the interaction check, it says caution advised: combo may decrease active tamoxifen metabolite levels & efficacy.

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Can I take supplements such as kelp while taking tamoxifen?

Yes, but why: Why are you taking supplements in the first place. Try good, healthy nutritional food. You won't need supplements.

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I refuse to take tamoxifen due to bad side effects. Is there a natural way of reducing my estrogen levels?

No: There may be other agents that reduce estrogen levels but none that have been shown to treat or prevent breast cancer. Therefore, use at your own risk.

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Can you take a B12 shot while on tamoxifen? Does tamoxifen have any affect on your thyroid? Thanks shannon

Yes, no probelm: Tamoxifen is a fairly harmless drug. It does not interfere with B12 or have any effect on the Thyroid gland.

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Is it safe to take ativan (lorazepam) with tamoxifen?

Call doctor: This is better addressed by your medical oncologist and your pharmacist. It also depends on your other medications.

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Is it ever recommended to "take a break" from the 5 years of tamoxifen if it might be causing depression?

Is it ever recommended to "take a break" from the 5 years of tamoxifen if it might be causing depression?

2 issues: I think there are 2 issues. 1) optimal breast cancer adjuvant hormone treatment. At 5 yrs of tam it might (if post menopausal) be a good time to switch to an aromatase inhibitor (ai) or the absolute benefit of >5yrs of tam or ai may be limited (depends on cancer characteristics). 2) is it depression or something else. If depression is it from tam or? . It could be that counseling +/- rx is needed.

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I take tamoxifen and recently have been having a heat sensation in my right foot?

I take tamoxifen and recently have been having a heat sensation in my right foot?

Tamoxifen: Tamoxifen can cause hot flashes but shouldn't single out one part of the body only. Is there any skin color change on the right foot? Perhaps there is some irritability of the superficial nerves there giving you the sensation of heat.

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Is it bad to share the same drink my mom takes her tamoxifen with for fear some residue will get inside me?

Is it bad to share the same drink my mom takes her tamoxifen with for fear some residue will get inside me?

Not a risk: The amount of tamoxifen transferred by using the same drinking vessel is not likely to pose any health risk. However, it would be better to not share utensils for reasons of hygiene. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine.

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Is it safe to take evista (raloxifene) after five years of tamoxifen and five years of aromasin?

Is it safe to take evista (raloxifene) after five years of tamoxifen and five years of aromasin?

Maybe. Continued: ... Aromasin, which prevents the formation of estrogen, is effective in reducing the risk of recurrence of breast cancer, but after 5 years, you are very likely to have sustained bone loss due to its effect. Evista (raloxifene) will arrest bone loss, and certainly is very unlikely to increase the risk of breast cancer, but it has never been studied as an advujant preventative like tamoxifen and aromasin.

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