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Doctor insights on: How Long Does Plavix Stay In Your System

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How long does plavix (clopidogrel) stay in system?

How long does plavix (clopidogrel) stay in system?

7 days: We usually ask patients to stop Plavix (clopidogrel) 7 days prior to a procedure to prevent bleeding. So the effect of Plavix (clopidogrel) lasts 7 days. ...Read more

Dr. Mathew Chengot
338 Doctors shared insights

Plavix (Definition)

Plavix is a platelet inhibitor is a kind of anti-coagulation drug ...Read more


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How long does it take to get plavix (clopidogrel) out of your system I took it for 31/2 months?

How long does it take to get plavix (clopidogrel) out of your system I took it for 31/2 months?

Double question: The active metabolite has an elimination half-life of about eight hours. Following an oral dose of 14c-labeled clopidogrel in humans, approximately 50% was excreted in the urine and approximately 46% in the feces in the five days after dosing. Because Plavix works by irreversibly inhibiting a receptor on platelet cell membranes, the effect of the drug will linger even though the drug is gone. ...Read more

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If plavix (clopidogrel) is out of system after 33 hrs, why would dr. Want you off for 7 days for medical procedures where you could bleed?

If plavix (clopidogrel) is out of system after 33 hrs, why would dr. Want you off for 7 days for medical procedures where you could bleed?

Effect on platelets: Has irreversible effect on platelets so must clear the drug from your system before you have operative procedure. Effect lasts longer than the half life of the medication in your blood. ...Read more

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How long post-stroke take plavix (clopidogrel)? 3 month or more?

How long post-stroke take plavix (clopidogrel)? 3 month or more?

Depends: It depends on the indication. Usually if prescribed post stroke, one stays on clopidogrel indefinitely unless there are severe side effects. Some physicians prescribe it for few weeks or months and then switch to some other medication (aspirin, for example). Please ask your doctor what was the indication. ...Read more

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A semi-consious patient needs to do Endoscopy, how long shall he stop using plavix before & after the procedure? He has been using it for 20 years.

A semi-consious patient needs to do Endoscopy, how long shall he stop using plavix before & after the procedure? He has been using it for 20 years.

Plan: All these questions must be answered by your doctor who know this exactly patient with complex medical condition. Gastroenterologist and anesthesiologist are doctors, who responsible for providing this information. ...Read more

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Been on plavix (clopidogrel) 75 mg since december (switched from effient) dr. Will now stop after a year. How long until the plavix (clopidogrel) is out of my body.

Plavix (clopidogrel) out: Plavix (clopidogrel) is rapidly with absorbed-peak plasma levelsof the main circulating metabolite occurring in~1hr. In humans, 50% excreted in urine and ~ 46% in feces five days after dosing. Plavix (clopidogrel) effect lasts for the life of the platelet (~ 7–10 days). ...Read more

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I have a total of 6 stents, how long should I expect to be on plavix (clopidogrel) or other blood thinning medication?

I have a total of 6 stents, how long should I expect to be on plavix (clopidogrel) or other blood thinning medication?

Depends: It doesn't matter so much how many stents you have but why you have them, what do you your other arteries look like and when were they put in. For instance, if a patient had stents for a heart attack and got 2 stents and then got 2 more 8 months later and then another 2 in a year, I might recommend life long antiplatelet treatment with Aspirin (81 mg) and plavix (clopidogrel). ...Read more

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How long should I take plavix and/ or eliquis after stent implant?

How long should I take plavix and/ or eliquis after stent implant?

Cardiologist: This is question for your cardiologist as there are different guidelines depending on the stent put in. ...Read more

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I am due for an outpatient surgery, how long should I be off plavix (clopidogrel) and 81 mg aspirin before the surgery?

I am due for an outpatient surgery, how long should I be off plavix (clopidogrel) and 81 mg aspirin before the surgery?

Depends: It depends on the type of surgery. It also depends on the reason you are on these medication for. It would be prudent to check with your doctor. ...Read more

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How long does it take for stomach biopsy to heal while taking Plavix (clopidogrel)?

No Change: Plavix (clopidogrel) dos enot affect wound healing. You are more prone to bleeding when taking plavix (clopidogrel) and if there is no bleeding a wound woul dheal in the same time frame as someone not taking plavix (clopidogrel). ...Read more

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If a person, senior citizen, is on a blood thinner plavix (clopidogrel) or baby asperin, does a wound take longer to heal?

Not necessarily: Blood thinners such as Plavix (clopidogrel) and Aspirin do not impair normal wound healing. As one ages- definitely the wound healing capability is impaired. This is secondary to higher rates of diabetes, cv disease, and other metabolic disorders. ...Read more

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Yesterday I had a BM that looked like coffee grounds and also real long snake BM is this serious? I take plavix (clopidogrel) and baby aspirin. Emilie

Yesterday I had a BM that looked like coffee grounds and also real long snake BM is this serious? I take plavix (clopidogrel) and baby aspirin. Emilie

This is Serious: Black 'coffee ground' BM which also has characteristics of being long (which could be sticky/tarry) is concerning for bleeding in the gastrointestinal tract, especially in someone on 2 anti-platelet medications which 'thins' the blood.
The medical term for black stool from blood is called melena.
There are also other causes for black stools, but the worrisome cause needs to be evaluated. ...Read more

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My husband has 3 medicine coated stents and has been on plavix (clopidogrel) since. How long does he have to stay on plavix (clopidogrel)? His bruising and bleeding is unreal!

Typically: The recommendation after receiving drug coated stents is dual antiplatelet therapy for 1 year. That is Aspirin and drugs like plavix (clopidogrel). Certainly there will be exceptions for many reasons. See your cardiologist before stopping any meds. There is a real risk of the stent thrombosing if Plavix (clopidogrel) is stopped too soon. ...Read more

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Would I be eligible for ultrasonic liposuction with the medication I'm taking? I am a woman in my 40's. I am no longer taking warfarin, but I am taking plavix (clopidogrel) as part of my anticoagulant drug regimen and I would like fat removed from my butt

Would I be eligible for ultrasonic liposuction with the medication I'm taking? I am a woman in my 40's. I am no longer taking warfarin, but I am taking plavix (clopidogrel) as part of my anticoagulant drug regimen and I would like fat removed from my butt

Maybe...: You will need to make sure that you are medically fit to proceed with elective surgery. Also, you will need to make sure that you are off all blood thinners. The doctors who know you best will be able to evaluate your situation and provide you with recommendations based on safety first. Best wishes. ...Read more

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My father (75) had a brain stroke 10 months ago and he has been on plavix (clopidogrel) all this time. For how long should he stay with it? Can he pass to aspirin?

My father (75) had a brain stroke 10 months ago and he has been on plavix (clopidogrel) all this time. For how long should he stay with it? Can he pass to aspirin?

Prevention: Would not recommend aspirin, as the data shows relatively mediocre results unless he would take one full asa, 325mg four times daily, which could cause gastritis and bleeding. Based on research data, the most successful protection against a subsequent stroke comes from Aggrenox twice daily, and if it were my dad, I would consider this first. ...Read more

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Can Plavix replace Eloquis or Zarelto & is it milder than the two?

No. Arterial vs veno: Plavix represents an entirely different class of blood thinners than Eliquis & Xarelto. Plavix (Clopidogrel) is an ARTERIAL blood thinner & stabilizes cholesterol plaques that are found in arteries. Eliquis / Xarelto are VENOUS (atrial) blood thinners that prevent pooled blood from clotting. The choice depends on the type of disease (arterial or venous?). TTYD or use HealthTap Prime to discuss. GL ...Read more

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Half life of plavix 300 mg. Procedure cancelled. How much plavix to give after rescheduled proc 24 hours later?

Plavix: Since plavix' effect on platelets can last up to 10 days, the dose on resumption depends upon how long it was discontinued preoproperatively. If it was held for only a week or less, I would resume it at a one daily dose. Your pharmacist may be able to better answer your question, however. ...Read more

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What u think about plavix (clopidogrel)?

What u think about plavix (clopidogrel)?

Useful: Plavix (clopidogrel) is a very good medication for some conditions, and is a required medication for others (if you have a certain type of heart stent, for example). As with all medications, only careful discussion with your doctor can determine if it is right for you. ...Read more

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Is too much plavix (clopidogrel) harmful?

Plavix (clopidogrel): Plavix (clopidogrel) is used for specific purpose in specific doses. Some people do require more Plavix (clopidogrel) dose than others. Too much Plavix (clopidogrel) can be associated with too much bleeding. ...Read more

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Please describe the medication: plavix (clopidogrel)?

Please describe the medication: plavix (clopidogrel)?

Anti platelet med: Clopidogrel is an anti platelet medication that irreversibly binds to a receptor on the platelet to make it have decreased capability of sticking to another platelet or the endothelial lining of a blood vessel. Used in the treatment of heart attacks and strokes to decrease recurrent events. ...Read more

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Why can't plavix (clopidogrel) be injected?

Liver activation: Plavix (clopidogrel) is a pro-drug which is inactive. Upon oral administration, Plavix (clopidogrel) is activated in the liver to become the active drug, injection of Plavix (clopidogrel) will bypass the liver activation of phase of the drug. Clinical studies of Plavix (clopidogrel) were done with oral administration, there are however other medications used in the hospital setting that are injectable, however used in the setting of heart attacks ...Read more

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Which is better for strokes==plavix or aggrenox?

Which is better for strokes==plavix or aggrenox?

Both good: Plavix (clopidogrel) needed if you have carotid stent. Your doctor will help you choose. ...Read more

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Gerd and taking plavix (clopidogrel) what helps?

Gerd and taking plavix (clopidogrel) what helps?

PPI + Plavix (clopidogrel): Is ok, but proton pump inhibitors (omeprazole) makes Plavix (clopidogrel) less effective. You may need to consider making changes to your lifestyle: a healthy weight, quitting smoking, drinking less alcohol, or not eating foods that make gerd worse.
Rec.: talk to your pcp about medication adjustment. ...Read more

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What are the effects of Plavix (clopidogrel) on stomach?

What are the effects of Plavix (clopidogrel) on stomach?

Easy bleeding: Of course, the purpose of Plavix (clopidogrel) is to prevent blood clots by inhibiting the ability of platelets (tiny blood cells) to clump together. Plavix (clopidogrel) doesn't really irritate the stomach, but is dangerous because it will cause an inflamed/irritated stomach lining, caused by ulcers/gastritis, etc, with many blood vessels close to the surface, to bleed. Plavix (clopidogrel) should not be taken in these conditions. ...Read more

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What is Plavix (clopidogrel) used for?

↓ Blood Clotting: Plavix (clopidogrel) inhibits platelets (usually the first step in blood clotting) from becoming activated: sticking to tissue, attracting other platelets to stick & activating the 12 clotting proteins (which act in a chain reaction) to form thrombin which polymerizes & ties everything together into clots. Plavix (clopidogrel) has no affect on blood viscosity; it is an anti-coagulant; it does not thin blood viscosity. ...Read more