Doctor insights on:
How Long Does Neuropathy Last After Taxol Chemo
My mom is undergoing chemotherapy-currently taxol- for breast cancer-is neuropathy that comes and goes a normal side effect?
A complete nerve transection will leave an area totally numb. The distribution of the numbers depends upon where the nerve was cut. A partial nerve injury may leave the area tingly or incompletely numb. Finally even if the nerve is not cut the swelling and bruising to the tea can affect the nerve as well. Usually we consider sharp penetrating injuries as likely having nerve lacerations when sensation is lost. A hand surgeon can examine the hand and pinpoint the site or extent of nerve injury and recommend ...Read more
Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug, protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more
What to do if I have severe neuropathy in both feet following chemo treatment for colon cancer. How long will it last?
Unknown: It could last a yea or forever. ...Read more
Having peripheral neuropathy 1 leg and foot for several weeks. Last chemo 2 years ago and am on tamoxifen now. Any ideas how to minimize the discomfort?
How long will I need to take vitamin B6 for peripheral neuropathy that was caused by chemotherapy?
Finished my last Taxol (paclitaxel) chemotherapy last week, having a side effect of my fingers swelling, swelling hurts, what can I do to stop the pain & swelling?
Hand swelling and pain: This is most likely side effect of Taxol (paclitaxel). Some side effects of taxol (paclitaxel) are neuropathy which is damaging of the nerve fibers joint pains and sometimes swelling of extremities. Most of this side effects get better after stopping the treatment but the neuropathy sometimes persists and requires lifelong medications. Follow up with your oncologist and discuss this problem. ...Read more
Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more
Difficult to treat: However, nerve pain medications like Gabapentin or Lyrica (pregabalin) can be beneficial. Some medications that can also be used as anti-depressants, such as Cymbalta or Effexor can be used as well. Topical pain creams containing ketamine can be helpful in treating chemo induced polyneuropathy as well. ...Read more
Is autonomic neuropathy common after chemo? If you can develop it from chemotherapy, will it go away eventually?
Can happen: Autonomic neuropathies do occur with some chemotherapy treatments, but is less common than the sensory or sensorimotor neuropathies. The prognosis is dependent on the level of change, intensity of chemotherapy, and whether modifications of the chemotherapy were given as well as if treatment was initiated. See your oncologist and discuss the issue. ...Read more
Oncologist told me to take sublingual b 12 for post chemo neuropathy. What dosage is recommended?
Maybe: Zostrix (capsaicin) 0.075% applied as a cream 3-4 times a day can help for neuropathic pain. It needs to be used for 10-14 days before becoming effective and initial applications can burn a bit. Pretreatment with a Lidocaine based gel beforehand can help prevent the zostrix (capsaicin) pain as well as help numb the painful area on its own. ...Read more
Will a taxane for chemo cause permanent peripheral neuropathy if hereditary pn in family? Any alternative to taxane?
Depends: Taxanes may cause permanent neuropathy in any patient although uncommon. There is increased intolerance to taxanes and preexisting sensory neuropathy. Unless the individual is effected by hereditary neuropathy I am not aware of any data suggesting an increased risk just because the family is affected. Whether taxanes can be replaced depends on disease and for what purpose it is used. ...Read more
Got neuropathy after chemo 5 yrs ago; gone in 3 mo. Bak 2 yrs ago & now. Neuro md said could return for lifetime. Worry or not? Neuro md or fp? Worse
Most commonly presented as numbness/decreased sensation and tingling on your fingers and toes (stocking-glove pattern). When it is worse it can then be presented as pain / discomfort on your hands and feet. (painful neuropathy). Sometimes, particular chemotherapy like oxaliplatin also can give you cold induced pain.
Chemo induced neuropathy - usually is accumulative. ...Read more
Does gabapantin use have a goal? Is there a point where I'm cured of post chemo neuropathy? Can I take metanx with I t? Chemo 1999.Numb feet 3 years.
Neuritic pain: Chemo damages nerves. They can die, recover fully, or partial recovery with dysesthesia. Gabapentin (neurontin) helps during recovery to reduce pain. Once recovery period is over medication rarely helps. You are well past recovery period. Gabapentin should not affect other meds. ...Read more
What is the most effective treatment for neuropathy and swollen hands that is caused by oxiplaten (a chemo drug)?
Difficult to treat: There are 2 forms acute and chronic. There are mixed benefits from use of calcium and magnesium infusion in the acute situation. The drug venlafaxine, an antidepressant has had some benefit in both situations. There are other drugs like Amitriptyline and Gabapentin has been helpful in some cases. It is hard to treat. It may very slowly improve if the drug is stopped. ...Read more
I get into bed at night, the skin on my lower legs feels sensitive for a few mins. I have foot / leg neuropathy (6 yrs) re chemo & am sick right now.?
Discuss with doctor.:
Many cases of the perepheral are ideopathic, meaning no identifiable cause, but chemotheraphy and diabetes are common reasons. You have not mentioned whether you are receiving chemo now and what kind of illness you have now.
Post chemotheapy neuropathy can be managed by multiple nerve pain pill including antipressant medications like Duloxetine and anti seizure drugs like gabaoentin. ...Read more
I have severe neuropathy pain as a result of radiation & chemo for colorectal cancer Stage IIIB. Taking Neurontin. Tried Lyrica (pregabalin). Nothing is helping.
I injured l shoulder 4 july & still severe pain shoulder/neck/chest wall. No fracture or tissue damage on mri. I have chronic peripheral neuropathy post chemo 2007 & 2009, bilateral mastect. Pls help!
Paclitaxel: Paclitaxel or Taxol (paclitaxel) is a micro tubule inhibitor. It has great activity in breast cancer. Side effects include low blood counts, hair loss, numbness and tingling which may persist despite stopping the drug. Typically given either weekly or every other week in breast cancer. It is mixed with a chemical called cremophor which can cause an allergic reaction so patients are monitored. ...Read more
Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more
I'm taking Taxol (paclitaxel) chemotherapy, my lips and skin are now drying out. What can I use to ease this problem?
Lips and skin:
Pharmacists are, in my opinion, the best folks to help you select the best 'over the counter" creams for your lips and something else for your skin.
If you decide to go that route please let me know how things are going. ...Read more
Comp 16 weeks of taxol/herceptin. Diangosis with mult pe's recently and about to begin a/c chemo. Will this be possible with existing pe's in both lungs?
Yes: You have obviously survived the bilateral pulmonary emboli. You didn't mention being on Coumadin (warfarin) or any blood thinner but you should be if you are not (speak to your doctor). Hopefully, most of the clot on your lungs has dissolved. If you can't be on blood thinners for some reason, you could have a filter placed in your vena cava. Having cancer is a risk factor for having blood clots and pes. ...Read more
I have stage 4 tnbc before I was to start AC chemo my platelets were too low 85. Started Taxol (paclitaxel) for a week now my liver enzymes are too high 590?
If platelets were low before starting, il'd worry that you have spread to the bone marrow. In that case, you would get treatment anyway, no matter what the counts, in hopes of clearing the marrow. If your liver enzymes are high, there may be liver metastases.
I don't know your'e whole story, but I would strongly consider treating with something like Carboplatin and abraxane. Also check her2 again. ...Read more
AFTER taxol/A/C for breast cancer stage2, path result-Lympho vascular invasion-shouldn't chemo resolved this? What now?
Ask your oncologist!: You need to givel us more information...Did the tumor shrink on chemotherapy? How much. Shrinkage? If the tumor did not shrink much, that is a bad sign. But if it reduced in size substantially then you are on the right track. But your oncologist can address your questions and guide you better. ...Read more
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