Doctor insights on: How long does it take to get birth defects if on accutane
Accutane: Accutane is known to cause human fetal abnormalities. While a woman is on Accutane she should use one or two reliable forms of contraception to prevent conception. Accutane stays in the body for a long time, so after stopping Accutane contraception must be continued for at least 3 months. ...Read more
It WILL cause defect:
"The baseline population risk of malformations is 3-5%, but it increases to almost 30% in women exposed to isotretinoin during the first trimester of pregnancy." see http://www. Ncbi. Nlm. Nih. Gov/pubmed/19961047
Many are profound, horrible defects--absent ears, tiny brain, deafness and blindness. Effects may occur many months after a woman ceases taking it. ...Read more
Accutane: There are multiple birth defects associated with intrauterine exposure to accutane. There is a certain critical time in the pregnancy where the greatest amount of potential harm can occur. Genetic counseling is strongly recommended to determine what possible effects Accutane exposure could have. ...Read more
I took two Accutane pills on february 22 and 23. Each pill is 5 mg. I conceived on may 30. Should I be worried that my baby will have birth defect?
Category X: Isotretinoin (accutane) is a significant human teratogen. It's marketed for cystic acne & despite methods to try to avoid pregnancies, it still happens. However, it's not stored in tissue, the drugs clears after 5 days of ingestion, & luckily for you, it's too early to cause birth defects. Topical tretinoin has not been associated with teratogenic effects. Check with your doc to confirm the above. ...Read more
Does accutane has a dangerous side effect (such as fatal birth defects) in the future like 3-5 years after taking the medication?
No: pregnancy has to be avoided 1 month before starting treatment, during treatment and one month after stopping the treatment, need to use two methods of contraception if sexually active, before, during and after treatment. Check information on the 'ipledge' program. Other side effects than fetal problems, are numerous, and the drug should be used under strict medical supervision, best wishes ...Read more
Could a male's 9 mo Accutane use at age 16 years cause his unborn baby's diagnosis of congenital vsd 10 years later? Or other birth defects?
Unrelated: Any sperm that might be affected during use are long gone 9 years later. We have no data suggesting males use of Accutane relates sperm or causes any birth defect. The medication has a direct toxic effect to an embryo if consumed by the mother during pregnancy. Congenital vsd is one of the most common heart related defects & has a broad genetic basis & some recurrence risk. ...Read more
How does Accutane not affect your fertility after? It's so serious in causing birth defects while on the drug and messes up hormones, how is it safe?
Who says it's safe?: It is one of the more toxic drugs, and the only reason we use it is because for some people, the pain of living with severe acne makes its risks worthwhile. Accutane acts on rapidly growing tissues, which is why it is contraindicated in pregnancy; but it does not appear to be as toxic to ovaries and eggs as it is to an embryo or a fetus. ...Read more
Does roaccutane (accutane) medication for acne cause birth defects in a child if the father is taking it, not the mother?
Can topamax (topiramate) cause birth defect after been off it for 3 months or how long should I consider been off it for me to try to get pregnant?
Off 3 months-OK: If you have been off topamax (topiramate) 3 months, you should be fine starting to try to get pregnant. You should start prenatal vitamins now when trying, so when you do get pregnant, the growing baby has the benefit of those meds early in the first trimester. Best wishes. ...Read more
Prenatal vitamins: Vitamins don't help you conceive faster, but prenatal vitamins with at least 800 micrograms (mcg) to 1 milligram (mg) of Folic Acid lower the risk of spina bifida. Talk to your OB if taking anti-seizure meds or a family / personal history of birth defects; you may need 4-5 mg of folic acid. Avoid excess alcohol, smoking, marijuana & other drugs, and review any prescription meds with your doctors. ...Read more
How long after discontinuation of 100, 000IU vitamin A daily for 3 months is safe to get pregnant without causing birth defects?
Measure/monitor w MD: 29 year female asks, How long after discontinuation of 100, 000 IU vitamin A for 3 months is safe to get pregnant without causing birth defects because high synthetic Vitamin A >10, 000 IU increases the risk for birth defect many folds especially early in pregnancy 7 or 8 weeks. Cos Vit A is Fat soluble the amount in storage is unpredictable. Measure Blood level vit A & Monitor closely with your MD ...Read more
Depends on virus: Some localized viral issues like colds are very limited in their penetration into the body & don't have a blood phase. These are unlikely to affect a fetus. Those that have a blood phase, like german measles, can cause fetal loss, hearing & vision loss, cataracts & more. Effect is often influenced by the timing (before or after organs finished forming) & aggressive nature of the virus. ...Read more
Can the prolonged use of Pueraria Mirifica 500mg cause birth defects if in the future I decide to have children, even if I have stopped it?
Can the on and off or prolonged use of Megace (megestrol) ES cause birth defects if in the future you decide to have children? What are the concequences?
Call her!: Your geneticist probably recognized a pattern or a theme in the midline birth defects you have, and she then thought that your aorta might also have some similar difference in the way it was structured, especially since the heart and aorta are in the midline. But I'm just guessing. You absolutley should feel justified to call, email, or write to her and ask this important question. ...Read more