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Doctor insights on: How Long Does It Take For Neurontin To Work

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How long does it take for a dose of Neurontin (gabapentin) to work?

Depends: Adverse effects can unfortunately occur within an hour of a dose, but treatment benefit can take a couple of weeks to gauge. ...Read more

Gabapentin (Definition)

Also called neurontin, (gabapentin) is an anticonvulsant medication used to treat seizure, also for post-herpetic neuralgia & other neuropathic pains, as well as restless leg syndrome. It works by lowering excitation ...Read more


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Was prescribed Neurontin (gabapentin) 1200 mg a day. Does it help releive peripheral neuropathy symptoms and how long does it take to have an effect?

Was prescribed Neurontin (gabapentin) 1200 mg a day. Does it help releive peripheral neuropathy symptoms and how long does it take to have an effect?

Sometimes: Neurontin (gabapentin) can be an effective therapy for a peripheral neuropathy. It is not universally successful and you may need a higher dose before you can determine in this medication will help. ...Read more

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How long does Neurontin (gabapentin) take to take affect pain wise? Taking for neuropathic symptoms.

How long does Neurontin (gabapentin) take to take affect pain wise? Taking for neuropathic symptoms.

Quickly: Gabapentin (brand name neurontin) will be effective in about an hour after taking the first dose and lasts about 6-7 hours. If you have constant pain, then you will need to take it three or four times a day. The dose that patients need varies a lot, so if the medication does not help after several doses, call your physician to see about adjusting the dose. ...Read more

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All my prob's finally diagnosed fibromyalgia. Now how long till Neurontin (gabapentin) and meloxicam work? Been on them for four days now.

All my prob's finally diagnosed fibromyalgia. Now how long till Neurontin (gabapentin) and meloxicam work? Been on them for four days now.

Several weeks: Neurontin (gabapentin) dosage needs to be titrated upwards to tolerance over several weeks. Meloxicam should provide some relief sooner. Good luck. Thanks for trusting HealthTap! ...Read more

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Have spinal stenosis with budging lumbar discs. Have burning toes. Take Neurontin (gabapentin). It does not work after 3 weeks. Is drug right for stenosis!

No: Need an emg/ncv test to determine if the toes are affected by the disc issue

neurontin is usually rxed for neuropathic local pain. ...Read more

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I have had scoliosis surgery back in 1991, for the past few years I suffer from severe pain in the buttocks. I go for pain mana I take Neurontin (gabapentin) 300mg 3x a day and have been getting pain management and neither works

I have had scoliosis surgery back in 1991, for the past few years I suffer from severe pain in the buttocks. I go for pain mana I take Neurontin (gabapentin) 300mg 3x a day and have been getting pain management and neither works

Sub-subspecialist: You need another evaluation and should someone who sees a lot of pts that have or have been tx'd for scoliosis. Please be as extensive as possible and try to find pts that this doctor may have treated as even docs from great training programs turn out to be awful. ...Read more

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How long do the effects of neurontin (800mg) last?

How long do the effects of neurontin (800mg) last?

The half life. ..: Of neurontin, (gabapentin) or the time it takes for half of the drug to lose its pharmacologic activity, is 5-7 hours. So at about 6 hours, 400 mg of activity remans; after another 6 hours, 200 mg of activity remains. After 24 hours, less than 50 mg. One sixteenth of the original dose. May be still active in the body. Likely no one would experience any effects from this. Short answer: "all" gone in 24 hours. ...Read more

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Can you take Neurontin (gabapentin) and eat grapefruit?

Can you take Neurontin (gabapentin) and eat grapefruit?

Not recommended: Eating grapefruit is usually considered to be healthful. But it can interact with Neurontin (Gabapentin). The hazardous interactions can occur many hours after grapefruit is consumed, . Thus avoid grapefruit altogether while on Neurontin. Hope it helps. ...Read more

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How can Neurontin (gabapentin) work on the nerves to stop pain?

How can Neurontin (gabapentin) work on the nerves to stop pain?

Blocks glutamate: The exact mechanism is not fully understood. Neurontin (gabapentin) may work by binding to certain sites on nerve cells in order to block the release of glutamate. Glutamate in turn causes nerve cells to be abnormally excited and therefore accentuate pain. Does that help? ...Read more

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I was just prescribed neurontin (gabapentin). Is it more effective if I take with or without food?

Doesn't matter: Neurontin or Gabapentin is not dependent on whether you take it with or without food or even what types of food. This study (http://1.Usa. Gov/n5ysd2) actually looked at this issue and did not find any statistically significant differences. Best to take as directed by your doctor. Neurontin/gabapentin generally is best when taken in divided doses throughout the day. ...Read more

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My Dr upped my Neurontin (gabapentin). I was on 300mg TID, now I'm on 300mg BID&600mg 1x day, total of 1, 200Mg QD. Can I take the new dose spaced out like 300MG QID?

Ask your doctor: My best answer is ask your doctor who prescribed you the Neurontin (gabapentin). In my experience, the typical daily dosing of this medication is three times a day. When the dosing frequency is increased, patients tend to miss their doses (compliance decreases). Talk to your doctor and discuss your thoughts. ...Read more

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Is it ok to take Neurontin and coumadin (warfarin)?

Is it ok to take Neurontin and coumadin (warfarin)?

Yes: Neurontin is an anti-seizure medication. Coumadin (warfarin) is a blood thinner. There is no known drug interaction between them. ...Read more

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How long is it safe to stay on neurontin (gabapentin)?

How long is it safe to stay on neurontin (gabapentin)?

Neurontin (gabapentin): It is prescribed for a reason, and if it's helping, stay on it for as long as your doctor recommends. ...Read more

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I take Neurontin (gabapentin) for mood disorder. Is that effective?

Neurontin (gabapentin): Depends on the dose and what other mood stabilizers have been tried. Might be bit more effective as u take with klonopin (clonazepam). Review with your doc. ...Read more

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I started on 300mg of Neurontin (gabapentin) for RLS its only been 3 days but does nothing for me. How long before it will help and what is the max dose?

I started on 300mg of Neurontin (gabapentin) for RLS its only been 3 days but does nothing for me. How long before it will help and what is the max dose?

Some thots: The maximum effective dose is 2400 mg per day, and beyond that the med provides no added benefit. Horizant is a once daily gabapentin, at 600 mg which might do better, but I have had more success with Dopamine agonists such as Mirapex or requip (ropinirole). ...Read more

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I am having a fibromyalgia flare I usually take 2 Neurontin (gabapentin) at night, but pain is severe can I take another Neurontin (gabapentin) or what else can I do to help.

I am having a fibromyalgia flare I usually take 2 Neurontin (gabapentin) at night, but pain is severe can I take another Neurontin (gabapentin) or what else can I do to help.

Several actions: 30's female w. fibromyalgia has pain in bed & neurontin ineffective; uses Vicodin. Savella, (milnacipran) Cymbalta, & Lyrica approved for FM, which can be associated with Hypermobility Syndrome & pelvic ligament strain when reclined is common. Soft mattress, cannabis, yoga, & aquatherapy oft help FM patients. Opiates are discouraged. Muscle reconditioning paramount. Cannabis topical lotions useful for many. ...Read more

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Is it ok to take adipex and Neurontin (gabapentin) together?

See below: As far as I can review I see no drug interaction. Always check with your md if you are adding medications. ...Read more

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Can you take Neurontin (gabapentin) and adipex together?

Can you take Neurontin (gabapentin) and adipex together?

Yes: Adipex is a CNS stimulant. Neurontin (gabapentin) is an anti-seizure medication. There is no known drug interaction between adipex and neurontin (gabapentin). However, always consult your doctors before starting new medications. ...Read more

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Can long term Neurontin (gabapentin) use cause seratonin syndrome?

Can long term Neurontin (gabapentin) use cause seratonin syndrome?

Very unlikely: First, it is unusual for Neurontin (gabapentin) to cause drug-drug interactions of any kind. Futhermore, the maximum useful dose is below 2400 mg daily, and higher amounts will not provide any enhanced effects. So, on it's own, the drug is certainly unlikely to cause seratonin syndrome ...Read more

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Is Spironolactone and Neurontin (gabapentin) safe to take together?

Is Spironolactone and Neurontin (gabapentin) safe to take together?

Safe: No significant drug interactions between spironlactone and Neurontin (gabapentin). That said, keep all follow-up doctor appointments and let prescribing doc know promptly if you have questions or distress while on these meds. ...Read more

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Is it ok to take a lortab during the day for pain and the 300 mg Neurontin (gabapentin) at night before bedtime? I have been on Neurontin (gabapentin) for almost a week

Tred carefully: Lortab has narcotic in it. It will make you sleepy. Depending on your pain, you may want to take that at night. Would not take both Neurontin (gabapentin) and lortab together at night ...Read more

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Is it ok to take Neurontin (gabapentin) 900mg 3 hrs after a glass of wine?

Should be ok: Yes, this should be safe. There is no interaction, but both can make you feel sleepy. Be careful about your alertness if you need to drive. ...Read more

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Is it OK to take Soma and Neurontin (gabapentin) together for neuropathy pain?

Is it OK to take Soma and Neurontin (gabapentin) together for neuropathy pain?

Should be okay: Both medications can be sedating, so be careful about driving and balance problems, but they are often taken together. ...Read more

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Is it safe to take Ambien (zolpidem) and Neurontin together?

Possibly: They can be taken together but remember you are taking 2 meds which both cause sedation. Check first with the doctor who prescribed them. ...Read more

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Can I take 1mg mirapex (pramipexole) with 300mg Neurontin for RLS Neurontin is not cutting it?

Get checked: This answer would be best to come from your prescribing doctor. Your doctor may want to increase the dose of one medicine rather than starting a second medicine. ...Read more

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***PSYCHIATRY*** Does Neurontin (gabapentin) cause tolerance, where it loose its impact on anxiety? That's why I take it. I can't take Benzo because I got addicted

Tolerance unlikely: I would assume something else is going on. PTSD possible. Find a professional who can work through the possibilities. Relationship issues are in my experience the most common source of anxiety. Have you ever checked out Alanon? It can be helpful for anyone who has had an addiction. ...Read more

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Does Neurontin (gabapentin) work neuropathy or placebo. Effect?

Does Neurontin (gabapentin) work neuropathy or placebo. Effect?

Symptomatic only: Neurontin (gabapentin) does not cure any neuropathy, but does sudue some of the symptoms. It will help pain, tingling, burning, but does not improve strength or change reflexes. It is not a placebo, but is not a cure all either. ...Read more

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Is it ok to take Lyrica (pregabalin) and Neurontin? I use Neurontin to help me sleep at night. Won't take together just same day

Is it ok to take Lyrica (pregabalin) and Neurontin? I use Neurontin to help me sleep at night. Won't take together just same day

Avoid both for sleep: These medications will cause sleepiness but as a side effect. They can cause or worsen already existing sleep problems, not to mention affect your alertness while you are awake. If your problem falling asleep is due to pain, you will need better control of that during the day. Insomnia can result and sleep hygiene is the best way to help you sleep and may be combined with a safer sleep medication. ...Read more

Dr. Joseph Weiner
668 Doctors shared insights

Neurontin (Definition)

Neurontin is a seizure agent which is a kind of ...Read more