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Doctor insights on:
How Long Does It Take For Neurontin To Work
1
How long does it take for a dose of Neurontin (gabapentin) to work?
Depends: Adverse effects can unfortunately occur within an hour of a dose, but treatment benefit can take a couple of weeks to gauge. ...Read more
Gabapentin (Definition)
Also called neurontin, (gabapentin) is an anticonvulsant medication used to treat seizure, also for post-herpetic neuralgia & other neuropathic pains, as well as restless leg syndrome. It works by lowering excitation ...Read more
2
Was prescribed Neurontin (gabapentin) 1200 mg a day. Does it help releive peripheral neuropathy symptoms and how long does it take to have an effect?

Sometimes: Neurontin (gabapentin) can be an effective therapy for a peripheral neuropathy. It is not universally successful and you may need a higher dose before you can determine in this medication will help. ...Read more
3
How long does Neurontin (gabapentin) take to take affect pain wise? Taking for neuropathic symptoms.

Quickly: Gabapentin (brand name neurontin) will be effective in about an hour after taking the first dose and lasts about 6-7 hours. If you have constant pain, then you will need to take it three or four times a day. The dose that patients need varies a lot, so if the medication does not help after several doses, call your physician to see about adjusting the dose. ...Read more
5
All my prob's finally diagnosed fibromyalgia. Now how long till Neurontin (gabapentin) and meloxicam work? Been on them for four days now.

Several weeks: Neurontin (gabapentin) dosage needs to be titrated upwards to tolerance over several weeks. Meloxicam should provide some relief sooner. Good luck. Thanks for trusting HealthTap! ...Read more
6
Have spinal stenosis with budging lumbar discs. Have burning toes. Take Neurontin (gabapentin). It does not work after 3 weeks. Is drug right for stenosis!
No:
Need an emg/ncv test to determine if the toes are affected by the disc issue
neurontin is usually rxed for neuropathic local pain.
...Read more
7
I have had scoliosis surgery back in 1991, for the past few years I suffer from severe pain in the buttocks. I go for pain mana I take Neurontin (gabapentin) 300mg 3x a day and have been getting pain management and neither works

Sub-subspecialist: You need another evaluation and should someone who sees a lot of pts that have or have been tx'd for scoliosis. Please be as extensive as possible and try to find pts that this doctor may have treated as even docs from great training programs turn out to be awful. ...Read more
8
How long do the effects of neurontin (800mg) last?

The half life. ..: Of neurontin, (gabapentin) or the time it takes for half of the drug to lose its pharmacologic activity, is 5-7 hours. So at about 6 hours, 400 mg of activity remans; after another 6 hours, 200 mg of activity remains. After 24 hours, less than 50 mg. One sixteenth of the original dose. May be still active in the body. Likely no one would experience any effects from this. Short answer: "all" gone in 24 hours. ...Read more
9
Can you take Neurontin (gabapentin) and eat grapefruit?

Not recommended: Eating grapefruit is usually considered to be healthful. But it can interact with Neurontin (Gabapentin). The hazardous interactions can occur many hours after grapefruit is consumed, . Thus avoid grapefruit altogether while on Neurontin. Hope it helps. ...Read more
10
How can Neurontin (gabapentin) work on the nerves to stop pain?

Blocks glutamate: The exact mechanism is not fully understood. Neurontin (gabapentin) may work by binding to certain sites on nerve cells in order to block the release of glutamate. Glutamate in turn causes nerve cells to be abnormally excited and therefore accentuate pain. Does that help? ...Read more
11
I was just prescribed neurontin (gabapentin). Is it more effective if I take with or without food?
Doesn't matter: Neurontin or Gabapentin is not dependent on whether you take it with or without food or even what types of food. This study (http://1.Usa. Gov/n5ysd2) actually looked at this issue and did not find any statistically significant differences. Best to take as directed by your doctor. Neurontin/gabapentin generally is best when taken in divided doses throughout the day. ...Read more
12
My Dr upped my Neurontin (gabapentin). I was on 300mg TID, now I'm on 300mg BID&600mg 1x day, total of 1, 200Mg QD. Can I take the new dose spaced out like 300MG QID?
Ask your doctor: My best answer is ask your doctor who prescribed you the Neurontin (gabapentin). In my experience, the typical daily dosing of this medication is three times a day. When the dosing frequency is increased, patients tend to miss their doses (compliance decreases). Talk to your doctor and discuss your thoughts. ...Read more
13
Is it ok to take Neurontin and coumadin (warfarin)?

Yes: Neurontin is an anti-seizure medication. Coumadin (warfarin) is a blood thinner. There is no known drug interaction between them. ...Read more
14
How long is it safe to stay on neurontin (gabapentin)?

Neurontin (gabapentin): It is prescribed for a reason, and if it's helping, stay on it for as long as your doctor recommends. ...Read more
15
I take Neurontin (gabapentin) for mood disorder. Is that effective?
Neurontin (gabapentin): Depends on the dose and what other mood stabilizers have been tried. Might be bit more effective as u take with klonopin (clonazepam). Review with your doc. ...Read more
16
I started on 300mg of Neurontin (gabapentin) for RLS its only been 3 days but does nothing for me. How long before it will help and what is the max dose?

Some thots: The maximum effective dose is 2400 mg per day, and beyond that the med provides no added benefit. Horizant is a once daily gabapentin, at 600 mg which might do better, but I have had more success with Dopamine agonists such as Mirapex or requip (ropinirole). ...Read more
17
My Dr recently put me on Neurontin (gabapentin) for migraines. Along w many other meds. I am an rn, and I'm very hesitant to take this pill. Any knowledge will help?
See a neurologist: It will be best to see a neurologist who specializes in headache treatment ...Read more
18
I am having a fibromyalgia flare I usually take 2 Neurontin (gabapentin) at night, but pain is severe can I take another Neurontin (gabapentin) or what else can I do to help.

Several actions: 30's female w. fibromyalgia has pain in bed & neurontin ineffective; uses Vicodin. Savella, (milnacipran) Cymbalta, & Lyrica approved for FM, which can be associated with Hypermobility Syndrome & pelvic ligament strain when reclined is common. Soft mattress, cannabis, yoga, & aquatherapy oft help FM patients. Opiates are discouraged. Muscle reconditioning paramount. Cannabis topical lotions useful for many. ...Read more
19
Is it ok to take adipex and Neurontin (gabapentin) together?
See below: As far as I can review I see no drug interaction. Always check with your md if you are adding medications. ...Read more
20
Can you take Neurontin (gabapentin) and adipex together?

Yes: Adipex is a CNS stimulant. Neurontin (gabapentin) is an anti-seizure medication. There is no known drug interaction between adipex and neurontin (gabapentin). However, always consult your doctors before starting new medications. ...Read more
21
Can long term Neurontin (gabapentin) use cause seratonin syndrome?

Very unlikely: First, it is unusual for Neurontin (gabapentin) to cause drug-drug interactions of any kind. Futhermore, the maximum useful dose is below 2400 mg daily, and higher amounts will not provide any enhanced effects. So, on it's own, the drug is certainly unlikely to cause seratonin syndrome ...Read more
22
Is Spironolactone and Neurontin (gabapentin) safe to take together?

Safe: No significant drug interactions between spironlactone and Neurontin (gabapentin). That said, keep all follow-up doctor appointments and let prescribing doc know promptly if you have questions or distress while on these meds. ...Read more
23
Is it safe to take 200mg Neurontin (gabapentin) and 90 mg arcoxia at the same time?
Arcoxia: Not yet approved by fda for use in usa, it treats arthritis. I am not aware of adverse interactions here. ...Read more
24
I have to take a drug test in 2 days will Neurontin (gabapentin) show up as a norcotic?

No: Neurontin (gabapentin) is an anti-seizure medication, not a narcotic. ...Read more
25
I'm on small dose of methadone and dr. Gave me neurontin (gabapentin) for rls can I take them together?
Methadone/Neurontin: As prescribed, yes.
Get a more detailed answer ›
26
I take 300 milligrams of neurontin (gabapentin) and 3 milligrams of klonopin each day at the same time. Or do they cancel each other out?
OK to do. Ask: Your prescribing MD about this, but these two meds are not mutually negating. ...Read more
27
Is it ok to take a lortab during the day for pain and the 300 mg Neurontin (gabapentin) at night before bedtime? I have been on Neurontin (gabapentin) for almost a week
Tred carefully: Lortab has narcotic in it. It will make you sleepy. Depending on your pain, you may want to take that at night. Would not take both Neurontin (gabapentin) and lortab together at night ...Read more
28
Can I take a flexeril a couple of hours after taking Neurontin (gabapentin) (600 mg)? Both prescribed but at different times. Have taken Neurontin (gabapentin) for 3 months now.

Yes: Watch for sedation. Don't drive until you know how the combination will affect you. ...Read more
29
Can I take Luvox and Neurontin (gabapentin) for anxiety?

Yes: Sure, this is a good combination
Get a more detailed answer ›
30
Is it ok to take Neurontin (gabapentin) 900mg 3 hrs after a glass of wine?
Should be ok: Yes, this should be safe. There is no interaction, but both can make you feel sleepy. Be careful about your alertness if you need to drive. ...Read more
31
I take neurontin, (gabapentin) is it ok to take a multivitamin with my medication?

Yes: There is no interaction between multivitamins and neurontin (gabapentin). ...Read more
32
Is it OK to take Soma and Neurontin (gabapentin) together for neuropathy pain?

Should be okay: Both medications can be sedating, so be careful about driving and balance problems, but they are often taken together. ...Read more
33
Is it safe to take Ambien (zolpidem) and Neurontin together?
Possibly: They can be taken together but remember you are taking 2 meds which both cause sedation. Check first with the doctor who prescribed them. ...Read more
34
Can I take 1mg mirapex (pramipexole) with 300mg Neurontin for RLS Neurontin is not cutting it?
Get checked: This answer would be best to come from your prescribing doctor. Your doctor may want to increase the dose of one medicine rather than starting a second medicine. ...Read more
35
***PSYCHIATRY*** Does Neurontin (gabapentin) cause tolerance, where it loose its impact on anxiety? That's why I take it. I can't take Benzo because I got addicted
Tolerance unlikely: I would assume something else is going on. PTSD possible. Find a professional who can work through the possibilities. Relationship issues are in my experience the most common source of anxiety. Have you ever checked out Alanon? It can be helpful for anyone who has had an addiction. ...Read more
36
Does Neurontin (gabapentin) work neuropathy or placebo. Effect?

Symptomatic only: Neurontin (gabapentin) does not cure any neuropathy, but does sudue some of the symptoms. It will help pain, tingling, burning, but does not improve strength or change reflexes. It is not a placebo, but is not a cure all either. ...Read more
37
Could it help to take namenda (memantine) and Neurontin for nerve pain?

Yes and no: Neurontin is approved for it. But Namenda (memantine) has no fda approval for nerve pain. ...Read more
38
Hey doc. Can I take subutex with gabapentin? Or take the subutex a few hours after the neurontin?
Subutex gabapentin: Yes you can as long as both are written for legitimate reasons with a legitimate script. ...Read more
39
If I take a 600mg Neurontin (gabapentin) for insomnia at night and want to go to sleep at 9pm, what time should I take it?
7-8pm: Onset takes 1-2 hours, so between 7-8pm, though there are better medications for treatment of insomnia than neurontin (gabapentin). ...Read more
40
Is it ok to take Lyrica (pregabalin) and Neurontin? I use Neurontin to help me sleep at night. Won't take together just same day

Avoid both for sleep: These medications will cause sleepiness but as a side effect. They can cause or worsen already existing sleep problems, not to mention affect your alertness while you are awake. If your problem falling asleep is due to pain, you will need better control of that during the day. Insomnia can result and sleep hygiene is the best way to help you sleep and may be combined with a safer sleep medication. ...Read more
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