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Doctor insights on: How Long Does It Take For Antihistamines To Leave Your System

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Does antihistamine hdroxyzine harm the liver?

Does antihistamine hdroxyzine harm the liver?

No: While Hydroxyzine is metabolized by the liver, it's use does not harm the liver. If the individual has liver damage such as hepatitis, then the Hydroxyzine may not be metabolized as it should be and side effects such as sedation may be increased. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Does antihistamine hydroxyzine harm the liver?

Does antihistamine hydroxyzine harm the liver?

No: Don't exceed the maximum recommended dosage though. ...Read more

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How long does it take antihistamines to get out of your system? I was told not to take any for 1 week, but inadvertently did. Is 5 days enough time?

How long does it take antihistamines to get out of your system? I was told not to take any for 1 week, but inadvertently did. Is 5 days enough time?

Yes: Most antihistamines clear within 2 -3 days or less, 1 week is a precautionary measure to make sure that your system is clear, that's mainly if you are going to be skin tested for allergies to either drugs, inhalants (such pollens), or foods extracts ...Read more

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I take benadryl (diphenhydramine) everyday about 250mg not at once but during the day for chonic allergies. Been doing this for two years will this damage my liver?

I take benadryl (diphenhydramine) everyday about 250mg not at once but during the day for chonic allergies. Been doing this for two years will this damage my liver?

No, but...: That is really a lot of benadryl (diphenhydramine) and while it will not damage your liver it can have a lot of side effects such as fatigue, dry mouth, constipation and mental slowing. Discuss a change to a non-sedating antihistamine, nasal saline and some nasal steroids with your doctor and try to get off this large dose of benadryl (diphenhydramine). Singulair may also be helpful. ...Read more

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How long do antihistamines stay in your system?

72 hrs: The biologic effects no longer than 72 hours even though the drug may still be detectable for up to a couple of weeks with certain antihistamines. ...Read more

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Is taking antihistamine everyday bad for you in the long term? Will my immune system get impaired?

Is taking antihistamine everyday bad for you in the long term? Will my immune system get impaired?

No and no.: There are no known longterm sequellae from antihistamines. I would stick with the long-acting, non-sedating ones, such as Allegra and Claritin, (loratadine) since the short-acting ones can make you drowsy. Antihistamines do not affect the immune system in any measurable way. ...Read more

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My name's Julie. I'm not usually bothered by seasonal allergies I am this year. If you take enough antihistamines will it build up in the system?

My name's Julie. I'm not usually bothered by seasonal allergies I am this year. If you take enough antihistamines will it build up in the system?

Nasal allergies: Antihistamines can offer relief for mild symptoms and may build up. Nasal steroids (Namsacort and Flonase are nonprescription) are going to be more effective for most people. The nasal steroids usually take 2-3 days to start making a difference and reach full effect the in 2 weeks. They are best used regularly in the season. Prescription antihistamine nasal sprays that work in 30 minutes. ...Read more

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How long does it take for antihistamines to work on your itchy rash?

How long does it take for antihistamines to work on your itchy rash?

IF they work. Fast.: Oral and especially topical antihistamines may have a slight- if any- effect on itching and will be noticeable quite soon after use. ...Read more

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What amount of does take to get high off of diphenhydramine hci/antihistamine and how long does it take to kick in?

What amount of does take to get high off of diphenhydramine hci/antihistamine and how long does it take to kick in?

Varies: Varies with dose. Some people get sleepy at lower dose than others. Some people get jumpy instead, especially children. Also depends on interaction with other meds or alcohol or caffeine. ...Read more

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How long does it take for eustachion tube dysfunction from allergies to go away with antihistamines and steroid nasal sprays?

Depends: The opening depends on the patency at the nasopharyngeal area. Antihistamines by mouth do not decongest the nasopharyngeal area although nasal steroid if aimed laterally often does. The optimal decongesting effect from nasal steroid is at 5-7 day of daily use. If the problem persists, consult an allergist. ...Read more

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How many weeks does it take for claritin (loratadine) 10mg to work? How long should I give it a try before deciding to switch to a different antihistamine?

A few hours: Claritin (loratadine) should start working within a couple of hours. If it doesn't not help at all, then switching to another won't do you much good. If it does help somewhat, then you may try the other alternatives which may possess more antihistamine effect than Claritin (loratadine). ...Read more

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How long will it take for prolactin levels (17.5 in male) to drop after discontinuing high doses of antihistamine for three consecutive months that caused elevated numbers? Will hair stop shedding?

How long will it take for prolactin levels (17.5 in male) to drop after discontinuing high doses of antihistamine for three consecutive months that caused elevated numbers? Will hair stop shedding?

If it was: Due to the antihistamine, which a doubt, it should be relatively quickly over days. Also, it is unlikely that that is the cause of your hair loss. Check w/your doctor for other explanations for all of your concerns. ...Read more

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Is there any side effects when you take antihistamines for a longer period than a month?

Unlikely: Antihistamines are generally safe to take for prolonged periods of time, as long as you're taking the proper dose. These medicines are notorious for causing drowsiness, although some over the counter antihistamines are non-drowsy. ...Read more

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Is it OK to take multiple types of antihistamines within a 24-hour period? Nothing seems to work as long as advertised.

DETAILS?????: What are you treating? Which antihistamines? How many of each? There are easy answers after the details are given. No answer is possible without this information. For chronic urticaria I may manage it with 10 or 20mg cetirizine (Zyrtec) in AM and hydroxyzine at bedtime. I never use Benadryl (diphenhydramine) except as a sleeping pill. ...Read more

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How long to take antihistamines to get rid of hives?

How long to take antihistamines to get rid of hives?

Depends: If it is truly hives then you should notice an improvement soon after taking med....If no improvement or worsening then see your doctor. ...Read more

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I was thinking: not long ago I started to use antihistamines when needed. All of them make people tired but, can't they just take a nap to get energy?

Unlcear: True some antihistamines like Benadryl (diphenhydramine) can make you sedated and sleepy. I'm not too sure what your question is! Please rephrase your question. Thanks ...Read more

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Dr. Paul Carter
642 Doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more