Doctor insights on:
How Long Does It Take Esophageal Cancer To Develop
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Depends: Unfortunately esophageal cancer is an aggressive one but if u catch it early it has a better chance of not recurring. It all depends on the primary stage of the disease. Stage I is good. Higher stages have more chances of recurring. Every cancer is unique and u should discuss your particular case prognosis with your oncologist. Good luck. ...Read more
Depends on the stage: There are 4 stages of esophageal cancer. Stage i-iii can be considered operable if the patient is of good physical condition. Tumor growing through the esophagus and into surrounding lymph nodes (regional) would be stage iii and still potentially operable. Tumor involving unresectable structures like the heart or bone, or that have metastastasized to distant organs (like brain) are inoperable. ...Read more
Hi, I had a barium swallow x-ray in February, which was normal. Now having some minor issues. Also coughing some blood stained sputum, Is it possible for Esophageal cancer to be advanced now 10 months later. How long does it take to develop. Thanks.
Barium swallow: Barium swallow may miss esophageal cancer. Upper endoscopy is the gold standard for diagnosis. Coughing up blood is not a characteristic symptom of esophageal cancer but an examination of the mouth, posterior nasal area and throat as well as a tracheal, bronchial and lung evaluation if coughing up blood occurs. ...Read more
Several years: No lesion begins on initial transformation. There is a premalignant state where the cells appear normal and then a transformation to dysplastic cells which eventually convert to the malignant phenotype which is in-situ. Transformation to the invasive state takes a further period of months if not longer. An invasive esophageal cancer would probably take 3-5 years to evolve and become symptomatic. ...Read more
If you take Prilosec more than 6-8 weeks in a row, are you more likely to develop esophageal cancer?
Does occasional heartburn/acid reflux cause esophageal cancer? Or is it more caused by chronic, long term severe acid reflux?
Cancer from reflux: Chronic GERD can increase the risk of esophageal cancer by producing changes in the lining of the esophagus from acid burns. This is called Barrett's esophagus and can increase the risk of esophageal cancer. This occurs in long term acid reflux. If you have only occasional symptoms, you are less at risk. If your symptoms are chronic, however, it's a good idea to get checked out. Good luck. ...Read more
Late stage esophageal cancer, has mestastasized across lympth nodes, & into stage 4 liver, getting chemo now, how long can the person hopefully live?
Undetermined.: One day at a time. Although statistics can inform you what happened to other people with similar problems, ultimately how long a you are expected to live is speculative and unpredictable. Ultimately, if you are alive today, you are alive today. ...Read more
How much time for esophageal cancer to narrow tube to 6mm with breathing issues? My father gone 2 months after diagnosis. How long did he have tumor?
Can be quick:
Depends on level involved
depends on which type of cancer
these are very sneaky! And do not present early in their growth.
By the time symptoms, they are advanced, spread to adjoining bronchus, nodes, and metastasize.
Sorry, terrible disease with short survival even when caught. ...Read more
Dysphagia vs globus- what's difference & which is sign of esophageal cancer? Going on 3+ weeks, constant. Long history of GERD. Dr said no endoscopy needed.
Dysphagia is usually a problem with a neurologic cause. It is difficulty in swallowing to the point the person may aspirate in any of the phases of swallowing.
Globus is a problem with swallowing that is usually thought to be psychogenic in origin and is made worse by stress and anxiety. Re the GERD, see your doctor again and at your age you may not need an EGD. Ask the doctor why no endoscopy. ...Read more
My mom 79 has esophageal cancer with mets to liver. So far no symptoms, discomforts, normal life. How long she may have with or w/o treatment? Thanks.
Not long.: This is advanced stage because there are mets to the liver. It is therefore not resectable, so it would likely have to be treated with combination chemotherapy, radiation, and surgery. At any rate, 5 year survival in resectable disease is only about 20%, so this is likely less than that, and overall 5 year survival is about <5% due to advanced state of many cases. Try to make her comfortable. ...Read more
How common does heart burn cause esophageal cancer? I'm worried about it cause I get acid reflux a lot. How often can I take Zantac (ranitidine) 300mg will it cure
Rare: The majority of esophageal Ca's are in the cardioesophageal junction where stomach meets esophagus. This tumor is induced by h. pylori. This organism induces ulcers in mucosa which is repaired by influx of bone marrow stem cells. The helicobacter toxin then converts the stem cells to the malignant form which grows as a cancer. ...Read more
Depends on stage: There are 4 stages of esophageal cancer (with a and b subtypes for some). For stage I and iia, the upfront therapy is surgery or esophagectomy. For stage iib or iii, treatment is chemoradiation followed by surgery, or definitive chemoradiation. For stage iv, the treatment is chemotherapy, + /- radiation. ...Read more
Depends on the type:
Squamous cell carcinoma of the esophagus for the most part is casued by smoking, consuming alcohol, nitrosamines, such as pickled foods and smoked meats.
Adenocarcinoma is casued by acid reflux, which can lead to injury of the lining of the esophagus, causing barrett's metaplasia. Barrett's can lead to low grade, then high grade dysplasia, and finally esophageal adenocarcinoma. ...Read more
Slow or Fast: It can be slow or fast, but generally its a slow process. Esophageal cancer tends to be circumferential, like a donut. As it grows, the hole or lumen becomes smaller, and can make it diffiult for food, then liquids to pass through. The diamter of your esophagus can get as narrow as 6mm (18french) before one gets symptoms. ...Read more
Two major types: The most common in this country is adenocarcinoma. The second most common is squamous cell carcinoma. There are other very rare types such as melanoma, lymphoma and small cell. Also, esophageal cancer is categorized by location, i.e. Bottom third, middle third and upper third of the esophagus. The majority in this country are in the lower third. ...Read more
IV: There are 4 stages for esophageal cancer, with a and b substages. We use roman numerals. For stages I - iia, the treatment is the physically fit patient is surgery or esophagectomy. For stages iib and III the treatment is chemotherapy and radiotherapy, followed by surgery, or in patients who do not want surgery, chemoradiotherapy alone. For stage IV treatment is chemotherapy +/- radiation. ...Read more
Coughing in esophageal cancer is usually caused by airway (aka bronchus or wind pipe) irritation, most commonly by:
1. Aspiration (saliva and/or food going into the airway) due to obstruction of the esophagus by tumor
2. A large tumor pushing on or growing into the airway. ...Read more
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