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Doctor insights on: How Long Does Depakote Stay In Your System

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How long does Depakote stay in your system?

How long does Depakote stay in your system?

Depends, see below: The half life of valproate is 16 hours. Depending on your drug levels at the time you stopped taking depakote, and assuming you did not start a new medication that interfered with the metabolism of depakote, in three to five days your levels were likely approaching zero. ...Read more

Dr. Jeffrey Cohen
237 doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, ..Etc.It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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How long does Depakote stay in the system?

It varies: Normally accepted half life is 4-16 hours but one recent study reported 40 hour. This means 1/2 of the total in your system should be gone in up to 40 hours.. Another 1/2 of whatever is left will take another 40 hours and so on. So there is no one clear simple answer. Best guess is that it will probably be gone by 10 days but could be sooner. ...Read more

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How long can it take for Depakote to leave your system?

How long can it take for Depakote to leave your system?

Usually very brief: If you are taking the er form, would be gone within 5-7 days, but the common ir form, blood levels start dropping after 8-12 hrs, and likely no effect within 2 or 3 days. ...Read more

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How long dose Depakote take get out of your system. My hair was falling out so i stopped taking it 2 weeks ago. My hair is still falling out.

Typically should be: Out of your system by three days. If your hair is still falling, see your doctor to ensure that there is no other cause. ...Read more

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Hi how long will it take to get Depakote off my wife system before pregnant as she has stopped it this month though with the help of her doctor.?

Hi  how long will  it take to get Depakote off my wife system  before pregnant as she has stopped  it this month though with the help of her doctor.?

Less than a week.: Half-life elimination for Depakote (increased with liver disease): adults: 9-16 hours. That means that within a week after stopping depakote, it is completely out of your system. Your wife should be taking Folic Acid at 4-5 mg daily to prevent fetal anomalies for 6-52 weeks prior to conception! ...Read more

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As a young woman taking depakote, are there any advisories you would have toward my health? I've read that it can affect the reproductive system.

As a young woman taking depakote, are there any advisories you would have toward my health? I've read that it can affect the reproductive system.

Several risk factors: The medicine can promote ovarian cysts, imbalance female hormones, and affect metabolism of carnitine. If you were to become pregnant, definite chance of baby having spina bifida, and also mental retardation. More common side effects include weight gain, hair loss, tremors. Would suggest meeting with your doctor and discussing this thoroughly. ...Read more

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I'm bulimic and have been purging and taking laxatives. I haven't had my depakote er 750 mg for two days. Should it all be out of my system now?

Bulimia: I feel your distress. Purging and taking laxatives can affect your gastro-intestinal system. Depakote is for seizure disorders, manic episodes and for prevention of Migraine Its side effects can be— abdominal pain, Hyponatremia, loss/increased appetite, weight loss/gain, nausea, vomiting, diarrhea or constipation Your Health is Precious! Go to ER for Diagnosis, Consultations and Treatment. ...Read more

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How long take Depakote to be in your sistem?

Varies: On average it can take around 7-10 days for Depakote to reach a therapeutic level in your body. Depending on what you are taking it for, the desired clinical effect may take longer. ...Read more

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How long does it take for Depakote to be effective?

How long does it take for Depakote to be effective?

About 10 days: A steady state level with any change in dosing is obtained after about 10 days, but in terms of how long before you see a desired clinical effect it depends on what you are using it for (migraine, epilepsy, mood stabilization). ...Read more

Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more