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Doctor insights on: How Long Does Depakote Stay In The Body

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How long does Depakote remain in the body after it is stopped?

How long does Depakote remain in the body after it is stopped?

Varies: The time can vary depending on one's current Depakote level, type of Depakote (such as er) and if there is any liver impairment. To be on the conservative side, i would say 10 days or possibly sooner. ...Read more

Dr. Jeffrey Cohen
237 doctors shared insights

Divalproex (Definition)

Divalproex, is a seizure medicine, the generic name is valporic acid, it has been in the market as an antiseizure medicine for long time, it is a good medicine, helps to control almost all types of common seizures, partial, generalized, absence, myoclonic, atonic, ..Etc.It can be used as a mood stabilizer in psychiatric patients. It has adverse effects on the liver, ...Read more


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How long does it take for Depakote dr 500 mg to leave your body?

How long does it take for Depakote dr 500 mg to leave your body?

45 to 80 hours: The half-life of Depakote er is 9-16 hours. This is the time for 1/2 the drug to be excreted from the body. After 5 half-lives more than 95% of the drug has been removed from the body. Note that other drugs or medical conditions such as liver or kidney disease could affect this estimate. ...Read more

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How long does Depakote stay in the system?

How long does Depakote stay in the system?

It varies: Normally accepted half life is 4-16 hours but one recent study reported 40 hour. This means 1/2 of the total in your system should be gone in up to 40 hours.. Another 1/2 of whatever is left will take another 40 hours and so on. So there is no one clear simple answer. Best guess is that it will probably be gone by 10 days but could be sooner. ...Read more

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How long does Depakote stay in your system?

Depends, see below: The half life of valproate is 16 hours. Depending on your drug levels at the time you stopped taking depakote, and assuming you did not start a new medication that interfered with the metabolism of depakote, in three to five days your levels were likely approaching zero. ...Read more

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How long take Depakote to be in your sistem?

Varies: On average it can take around 7-10 days for Depakote to reach a therapeutic level in your body. Depending on what you are taking it for, the desired clinical effect may take longer. ...Read more

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How long does it take for Depakote to be effective?

How long does it take for Depakote to be effective?

About 10 days: A steady state level with any change in dosing is obtained after about 10 days, but in terms of how long before you see a desired clinical effect it depends on what you are using it for (migraine, epilepsy, mood stabilization). ...Read more

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How long does it take for Depakote to start working?

How long does it take for Depakote to start working?

1-2 weeks: On average, for the treatment of psychiatric disorders, it takes 7-14 days after achieving a therapeutic blood level. I will defer to my neurology colleagues for commenting on how long it takes to start working for seizures and/or migraines. ...Read more

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How long can it take for Depakote to leave your system?

Usually very brief: If you are taking the er form, would be gone within 5-7 days, but the common ir form, blood levels start dropping after 8-12 hrs, and likely no effect within 2 or 3 days. ...Read more

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What effects does Depakote have on the human body?

Depakote: Some of the more serious effects include a severe skin reaction, weakness, easy bruising, lethargy, and confusion. Others include hair loss, vision changes, changes in menstruation, and GI upset. ...Read more

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If off of Depakote for several weeks, how long does it take to correct the QT syndrome?

QT prologation: with Depakote occurred with only 27 of 27 thousand people who had side effects in 2014 while taking Depakote according to one source. Of those who had it most were taking other medications as well. There is no data on how long it takes to recover. You might take this up with the prescribing doctor or a cardiac electrophysiologist. Short QT syndrome also occurs but just as rarely ...Read more

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Depakote (Definition)

Depakote is the brand name for a medication known as valproic acid. It is most commonly used to treat seizures, though it can also be used as a mood stabilizer in certain psychiatric disorders. It is used to treat multiple seizure types and can be used alone or with other seizure medications if needed. Common side effects include nausea, dizziness, ...Read more