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Doctor insights on: How Long Does A Hereditary Angioedema Attack Typically Last

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How long does a hereditary angioedema attack typically last?

How long does a hereditary angioedema attack typically last?

Can vary: Attack duration varies from person to person but typically lasts 3-5 days. ...Read more

Dr. Douglas Johnston
130 doctors shared insights

Angioedema (Definition)

A condition in which swelling occurs under the skin. Angioedema is due to fluid leaking from blood vessels usually due to an ...Read more


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At what age do attacks of hereditary angioedema start?

Most before puberty: 40% of individuals with hereditary angioedema (hae) have attacks before age 5 and 75% have attacks before age 15. Swelling is not itchy and there are no hives in hae. Frequency of attacks increases after puberty. Diagnosis usually made in 2nd or 3rd decade of life by history with confirmatory blood tests. See your md for diagnosis and if indicated preventive treatment. ...Read more

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When would you consider hereditary angioedema attacks serious?

When would you consider hereditary angioedema attacks serious?

Close the airway: Hereditary angioedema is characterized by episodes of tissue swelling in the face, throat, limbs, and abdomen. In most cases, the swelling develops over hours but sometimes it may take only minutes. The most serious attacks swell the throat closed which can quickly cause respiratory arrest & death if not treated. Frequent & unpredictable attacks are also serious and require preventative treatment. ...Read more

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What's hereditary angioedema?

Genetic disorder: HAE is genetic disorder resulting in unpredictable swelling of any part of the body. It is not caused by histamine, but a chemical caused bradykinin. When released in uncontrolled manner the part of the body where this occurs swells. Swelling occurs within 6-36 hours and if untreated resolves in 2-5 days. There is now a replacement enzyme for Type I and II. 4 on demand meds are FDA approved. ...Read more

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What cause hereditary angioedema?

HAE: Hereditary angioedema (hae) is caused by a uncontrolled activation of a complex cascade of proteins called complement. Hae is a result of a deficiency or lack of functional c1 esterase inhibitor protein. Some patients are born with this problem while other may acquire a lack of c1 esterase inhibitor from an underlying disease such as cancer. There are new treatments available. ...Read more

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Can anyone have hereditary angioedema?

Can anyone have hereditary angioedema?

Yes: Hereditary angioedema types 1 and 2 have a very strong genetic component and typically runs in families. However, spontaneous mutations can occur and hae i and ii can occur on anyone. ...Read more

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What causes hereditary angioedema to occur?

What causes hereditary angioedema to occur?

Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may too prone to swelling problems which can be life threatening. ...Read more

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Anyone here treat hereditary angioedema(hae)?

Anyone here treat hereditary angioedema(hae)?

allergists can help: There been exciting and new pharmaceutical options developed for the treatment of acute attacks of hereditary angioedema. Typically, board certified allergists are well-versed in the diagnosis and management of hereditary angioedema. ...Read more

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Does anyone have experience with hereditary angioedema?

Does anyone have experience with hereditary angioedema?

Hereditary angio ede: Hereditary angioedema (ha) is a disease that is typically noted to run in families. It is causes by low levels or poor function in a controller protein called c-1 esterase inhibitor. If swelling (angioedema) occurs with hives, then the angio edema is unlikely to be due to this rare problem. Typical angioedema develops quickly, often maximally within one hour. Ha may swell slowly over many hrs. ...Read more

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Is hereditary angioedema different from regular angioedema?

Is hereditary angioedema different from regular angioedema?

Allergy or not: Angioedema such as swelling of the tongue or lips can occur as the result of an allergy to food or medication. It is usually associated with hives (urticaria). The presence of hives essentially rules out the allergic cause making hereditary or acquired c-1 inhibitor deficiency likely. However, the lack of hives does not rule out allergy. See an allergist for further evaluation either way! ...Read more

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Hereditary angioedema — can anybody tell me anything about?

Abnl or absent prote: Hae is the result of missing or a poorly functioning protein called c1 esterase inhibitor. When this protein is missing or abnormal then a patient may too prone to swelling problems which can be life threatening. ...Read more

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When does prophylaxis for hereditary angioedema become necessary?

It depends: Great question. It really depends on two factors: 1. The severity of the reactions, and 2. The frequency of the reactions. When the reactions become too severe and/or too frequent, prophylactic treatment is recommended. Now, what does too severe/frequent mean? It depends on the person. Ultimately, when the reactions impact a patient's daily life, it's time to consider prophylaxis. ...Read more

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Is hereditary angioedema type III a genetic mutation?

Is hereditary angioedema type III a genetic mutation?

The big unknown: This is a big unknown question, some people have a mutation that can cause type iii and others have an unkown kind that response to treatments of hae. ...Read more

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I was tested for suspected Hereditary Angioedema. The results came back showing my C1-INH function 58% and antigen 59% (range 70-130). What does mean?

Probably: The findings are compatible with HAE especially in the presence of a low C4 level and compatible features of HAE. Many effective treatments are available and I think the next step is for you to consult an allergist for options in treating this potentially life-threatening condition. ...Read more

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C-1 inh is <40% of the expected norm but C4 level normal, wats this mean? Does this mean hav hereditary angioedema? Hx of swelling tongue, nose, lips, vomit

C-1 inh is <40% of the expected norm but C4 level normal, wats this mean? Does this mean hav hereditary angioedema? Hx of swelling tongue, nose, lips, vomit

Can't rule out: A normal C4 would be unusual for hae. You don't mention whether c1 inh level was functional activity or level of protein. Functional (activity) complement tests are extremely dependent on the way the specimen is handled. Both tests should probably be repeated. To sort things out, you should see a board-certified allergist immunologist. ...Read more

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How long can a chronic urticaria last? Apparentely it is related with hashimoto thyroiditis. Any idea? It's been 1year of hives and angioedemas.

How long can a chronic urticaria last? Apparentely it is related with hashimoto thyroiditis. Any idea? It's been 1year of hives and angioedemas.

Can be a long time: The association with hashimoto's thyroiditis is generally just thought to be that people who make antibodies to one thing inappropriately (thyroid) are more likely to make antibodies to other things inappropriately (mast cell receptors which can be a cause for urticaria). Most chronic urticarias last 2 weeks to 2 months, but 10-20% can last more than 2 years. ...Read more

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What other possible DX would there be if I've been told I don't fit hereditary or allergic angioedema profiles?

Need more info: With clinical presentation, one would be unlikely to have both hereditary and allergic angioedema in the same differential. The hallmark of one is lack of pruritis, and the other is pruritis. ...Read more

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What can I do to try to prevent idiopathic angioedema attacks? Mine occur every 1-2 months

What can I do to try to prevent idiopathic angioedema attacks? Mine occur every 1-2 months

See allergist: Consult an allergy/immunology specialist who can test for underlying conditions which cause angioedema (ae). If any exist then treating the underlying condition will prevent ae. If no underlying cause found then there are many medications which can be used in combination to control the ae. There are several new meds available for ae which may be useful. ...Read more

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Can asthma meds (inhaled cortisteroids) be used to treat frequent attacks of angioedema with swollen airways?

Unfortunately no: Angioedema threatening the airways can only be helped first by Epinephrine (adrenline), then by high dose systemic steroids, inhaled corticosteroids won't help the acute phase. ...Read more

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My dr diagnosed idiopathic angioedema of my lips (had hives 8 months ago)It's been 30hrs, swelling slightly less.how long to go down? Compress? H or C

Depends on cause: Most angioedema should subside by 30 hrs. If you have had recurrent bouts of angiioedema lasting for more than 2-3 days, then you need to get evaluated for hereditary angioedema. Do note that the cause may not be established despite extensive studies. If this was the fist episode, then it may or may not recur. See an allergist if the problem persists or worsens. ...Read more

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Taking perindopril ACE Inhibitor for essential Hypertension since last four years. Is it possible that there can be angioedema occurring now.

Taking perindopril ACE Inhibitor for essential Hypertension since last four years. Is it possible that there can be angioedema occurring now.

Edema: Ace inhibitors are a wonderful class of antihypertensive agents. However, known side effects include angioedema, other words fluid retention and low potassium levels. Allergic reactions can occur at any time during drug use, even after periods of no symptoms ...Read more

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Is it possible for angioedema to last for several weeks? The right side of my upper lip swelled dramatically two weeks ago and is slightly puffy still. I am following up with an allergy test in 2weeks

Angioedema: It usually lasts for a few days, 2 weeks is a bit long. Not sure it is angioedema, anyhow it needs to be checked. It may be a good idea to see your dentist too. ...Read more

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Every 2ish yrs for the last 10, I have an allergic reaction to something, but the cause is never determined nor clear. Angioedema ruled out last time. Could this be something other than an allergy? Symptoms: tight throat, extreme hives, itchy tongue.

Every 2ish yrs for the last 10, I have an allergic reaction to something, but the cause is never determined nor clear. Angioedema ruled out last time. Could this be something other than an allergy? Symptoms: tight throat, extreme hives, itchy tongue.

Urticaria/angioedema: is what you described, not sure what did you mean when you mentioned that angioedema was ruled out ! those recurrent acute attacks warrant keeping injectable epinephrine handy as well as antihistamines to use in case you need them again. You need to be evaluated by an allergist/immunonlogist, or a dermatologist, check aaaai.org or acaai.org for an allergist in your area, best wishes ...Read more

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Can kissing cause angioedema?

Possibly: Some rare forms of angioedema can be induced by "trauma" so be gentle. Some forms of angioedema are idiopathic and the trigger is not known. Frequently angioedema is associated with hives and may be from an allergic trigger. ...Read more

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Do people with angioedema have a lot of pain?

Do people with angioedema have a lot of pain?

Not necesarily: Depends on which part of the body is involved. Most of the cases you will feel itching and swelling. Scratching that area will lead to progressively worse swelling. ...Read more

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What are typical ways to prevent the onset of angioedema?

Avoid triggers, meds: Angioedema can be caused by an allergy to foods & medicines and prevention means avoiding the offending trigger. Angioedema can also be caused by an underlying condition & treatment of that condition decreases angioedema attacks. Angioedema can also be hereditary but sometimes no cause is found. In those cases, medications & blood products can prevent or decrease attacks. ...Read more