Doctor insights on:
How Long Does A Hereditary Angioedema Attack Typically Last
Can vary: Attack duration varies from person to person but typically lasts 3-5 days. ...Read more
Most before puberty: 40% of individuals with hereditary angioedema (hae) have attacks before age 5 and 75% have attacks before age 15. Swelling is not itchy and there are no hives in hae. Frequency of attacks increases after puberty. Diagnosis usually made in 2nd or 3rd decade of life by history with confirmatory blood tests. See your md for diagnosis and if indicated preventive treatment. ...Read more
Close the airway: Hereditary angioedema is characterized by episodes of tissue swelling in the face, throat, limbs, and abdomen. In most cases, the swelling develops over hours but sometimes it may take only minutes. The most serious attacks swell the throat closed which can quickly cause respiratory arrest & death if not treated. Frequent & unpredictable attacks are also serious and require preventative treatment. ...Read more
Genetic disorder: HAE is genetic disorder resulting in unpredictable swelling of any part of the body. It is not caused by histamine, but a chemical caused bradykinin. When released in uncontrolled manner the part of the body where this occurs swells. Swelling occurs within 6-36 hours and if untreated resolves in 2-5 days. There is now a replacement enzyme for Type I and II. 4 on demand meds are FDA approved. ...Read more
HAE: Hereditary angioedema (hae) is caused by a uncontrolled activation of a complex cascade of proteins called complement. Hae is a result of a deficiency or lack of functional c1 esterase inhibitor protein. Some patients are born with this problem while other may acquire a lack of c1 esterase inhibitor from an underlying disease such as cancer. There are new treatments available. ...Read more
Hereditary angio ede: Hereditary angioedema (ha) is a disease that is typically noted to run in families. It is causes by low levels or poor function in a controller protein called c-1 esterase inhibitor. If swelling (angioedema) occurs with hives, then the angio edema is unlikely to be due to this rare problem. Typical angioedema develops quickly, often maximally within one hour. Ha may swell slowly over many hrs. ...Read more
Allergy or not: Angioedema such as swelling of the tongue or lips can occur as the result of an allergy to food or medication. It is usually associated with hives (urticaria). The presence of hives essentially rules out the allergic cause making hereditary or acquired c-1 inhibitor deficiency likely. However, the lack of hives does not rule out allergy. See an allergist for further evaluation either way! ...Read more
HAE: It is part of the history from a specialist. How else will we know? ...Read more
It depends: Great question. It really depends on two factors: 1. The severity of the reactions, and 2. The frequency of the reactions. When the reactions become too severe and/or too frequent, prophylactic treatment is recommended. Now, what does too severe/frequent mean? It depends on the person. Ultimately, when the reactions impact a patient's daily life, it's time to consider prophylaxis. ...Read more
No: Not typically associated with hae.Get a more detailed answer ›
The big unknown: This is a big unknown question, some people have a mutation that can cause type iii and others have an unkown kind that response to treatments of hae. ...Read more
Yes: It is a factor XII issue which is encoded in your genome. ...Read more
I was tested for suspected Hereditary Angioedema. The results came back showing my C1-INH function 58% and antigen 59% (range 70-130). What does mean?
Probably: The findings are compatible with HAE especially in the presence of a low C4 level and compatible features of HAE. Many effective treatments are available and I think the next step is for you to consult an allergist for options in treating this potentially life-threatening condition. ...Read more
C-1 inh is <40% of the expected norm but C4 level normal, wats this mean? Does this mean hav hereditary angioedema? Hx of swelling tongue, nose, lips, vomit
Can't rule out: A normal C4 would be unusual for hae. You don't mention whether c1 inh level was functional activity or level of protein. Functional (activity) complement tests are extremely dependent on the way the specimen is handled. Both tests should probably be repeated. To sort things out, you should see a board-certified allergist immunologist. ...Read more
How long can a chronic urticaria last? Apparentely it is related with hashimoto thyroiditis. Any idea? It's been 1year of hives and angioedemas.
Can be a long time: The association with hashimoto's thyroiditis is generally just thought to be that people who make antibodies to one thing inappropriately (thyroid) are more likely to make antibodies to other things inappropriately (mast cell receptors which can be a cause for urticaria). Most chronic urticarias last 2 weeks to 2 months, but 10-20% can last more than 2 years. ...Read more
See allergist: Consult an allergy/immunology specialist who can test for underlying conditions which cause angioedema (ae). If any exist then treating the underlying condition will prevent ae. If no underlying cause found then there are many medications which can be used in combination to control the ae. There are several new meds available for ae which may be useful. ...Read more
Can asthma meds (inhaled cortisteroids) be used to treat frequent attacks of angioedema with swollen airways?
My dr diagnosed idiopathic angioedema of my lips (had hives 8 months ago)It's been 30hrs, swelling slightly less.how long to go down? Compress? H or C
Depends on cause: Most angioedema should subside by 30 hrs. If you have had recurrent bouts of angiioedema lasting for more than 2-3 days, then you need to get evaluated for hereditary angioedema. Do note that the cause may not be established despite extensive studies. If this was the fist episode, then it may or may not recur. See an allergist if the problem persists or worsens. ...Read more
Is it dangerous to do an at home allergy patch test? We're trying to figure out what caused my 22 y/o son to break out in hives and angioedema last week. We believe it might be a new laundry soap. Would it be dangerous to take a small 1-inch bandage, pu
Taking perindopril ACE Inhibitor for essential Hypertension since last four years. Is it possible that there can be angioedema occurring now.
Is it possible for angioedema to last for several weeks? The right side of my upper lip swelled dramatically two weeks ago and is slightly puffy still. I am following up with an allergy test in 2weeks
Every 2ish yrs for the last 10, I have an allergic reaction to something, but the cause is never determined nor clear. Angioedema ruled out last time. Could this be something other than an allergy? Symptoms: tight throat, extreme hives, itchy tongue.
Urticaria/angioedema: is what you described, not sure what did you mean when you mentioned that angioedema was ruled out ! those recurrent acute attacks warrant keeping injectable epinephrine handy as well as antihistamines to use in case you need them again. You need to be evaluated by an allergist/immunonlogist, or a dermatologist, check aaaai.org or acaai.org for an allergist in your area, best wishes ...Read more
Avoid triggers, meds: Angioedema can be caused by an allergy to foods & medicines and prevention means avoiding the offending trigger. Angioedema can also be caused by an underlying condition & treatment of that condition decreases angioedema attacks. Angioedema can also be hereditary but sometimes no cause is found. In those cases, medications & blood products can prevent or decrease attacks. ...Read more
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