Doctor insights on:
How Long Do Methadone Stay In Your System
Methadone half-life: The half-life of Methadone is 15 to 60 hours. It takes five times the half-life to leave your system. Therefore it could take anywhere between 75 hours to 300 hours to clear your system. This is with chronic use. The half-life for most people is approximately 25 hours meaning that would take approximately five days and five hours to leave your system completely. ...Read more
Long time: Methadone is very fat soluble and stays in your fatty tissue for a long time. If you have been taking it chronically then it may still there is a good chance it will still be there next wednesday. The real question is why you have taken methadone. If you were taking it to get high, that is a very bad choice. Methadone will get you dead before it will get you high. ...Read more
No: There are many drugs which inhibit methadone metabolism, and increase levels of drug in the bloodstream, There are also drugs which increase metabolism of methadone, reducing its effectiveness and half-life. However, methadone itself does not have either inhibiting or inducing effects on metabolic liver enzymes. ...Read more
Methadone: It depends on a number of factors: body weight, metabolism, amount used, etc. It is metabolized slowly and can "sit" in fats. The average time it takes to get "out of the system" is ~4-7 days. But it can still be detected in the urine or blood for up to 6 weeks after the last dose. ...Read more
Variable: Depends on how long you have been on this dose and if you were previously on a higher dose. Half life ranges from 8-59 hrs and may be released very slowly from fatty tissue and liver. ...Read more
Unclear on question: Do you mean how long would it take to get to therapeutic levels? That would be within the first day or two, and 80 is a hefty dose. T has a long half life, and will be in your system for as long as you take it. If that does not answer the question, I do apologize but i hope that helps! ...Read more
It depends: Methadone because it stays in the body's fat can remain detectable in the body for extended periods. Hair testing might show its presence for months. Most screening, however, is through urine and with standard cut-offs I would expect after a week it wouldn't come up as positive unless previous use was high or there was some significant problem effecting excretion. ...Read more
How long does methadone take to leave your system? On it for 2 months 5 mg twice daily. Got off yesterday
Variable: Methadone takes about three days to fill tissue reservoirs after a person begins taking it. The rate at which methadone leaves a person's body after she stops it is variable, but since you have been on it for two months although at a relatively low dose, it could be mostly out of your system by two to eight weeks, depending on your body chemistry. ...Read more
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