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Doctor insights on: How Long Do Cymbalta Withdrawal Symptoms Last

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How long do cymbalta (duloxetine) withdrawal symptoms last?

A Big Range: It could last upto two weeks, but it usually lasts four days. The best way to make sure you have no withdrawal symptoms is to taper down from 60mg to 40mg for 4 days, then 20mg for 4 days then stop. Some people tolerate going from 60-30-0. ...Read more

Dr. Stuart Wasser
168 doctors shared insights

Withdrawal Symptoms (Definition)

Withdrawal symptoms is a set of predictable symptoms that occur upon discontinuation of an addictive substance after regular ...Read more


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I've been on cymbalta (duloxetine) 3 weeks and want to go off it. Will I get withdrawal symptoms or it hasn't been long enough to get them?

I've been on cymbalta (duloxetine) 3 weeks and want to go off it.  Will I get withdrawal symptoms or it hasn't been long enough to get them?

Symptoms can occur: It is highly desirable for the dose to be tapered rather than stopped suddenly. The brain needs some time to adapt to the medication not being there and it is better for this to happen gradually. Three weeks would usually be long enough for the medication to have had sufficient effect to make tapering recommended. The actual taper may not need to be very long, just not a sudden stopping. ...Read more

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What are common withdrawal symptoms in the process and if cymbalta (duloxetine) really helps with fibromyalgia pain. How long does the process take?

What are common withdrawal symptoms in the process and if cymbalta (duloxetine) really helps with fibromyalgia pain. How long does the process take?

Varied time: The time to respond to cymbalta, (duloxetine) if a patient will respond, varies. Symptoms may begin to lessen within 2 weeks but it may takes months especially if the Cymbalta (duloxetine) needs to be increased, sometimes to 90mg or more if the Cymbalta (duloxetine) needs to be stopped it must be tapered down and not stopped abruptly or there may be withdrawal symp[toms or increased depression. ...Read more

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Dr said withdrawal symptoms from cymbalta (duloxetine) would last about 1 wk, it's been a month still dizzy, sick with major brain fog. What can i do? Unbearable

Is depression back?: Discontinuation syndrome ( or "withdrawal") from antidepressants usually lasts 1-2 weeks but it varies from person to person and can be complicated when other meds or conditions ( medical or psychiatric) are in the mix. When people continue to be symptomatic at 1 months it may be a relapse ( return) or the original symptoms. This is something to discuss and decide with your doctor. Good luck. ...Read more

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What are Cymbalta (duloxetine) withdrawal symptoms?

Varies: They can be completely avoided by coming off Cymbalta (duloxetine) in steps under supervision. If you suddenly stop take a high dose, you can develop "discontinuation" symptoms, which can include odd sensations, headaches, flu-like feelings, and gi discomfort. Then you might also have the return of the anxiety, depression, or pain that Cymbalta (duloxetine) was helping with. ...Read more

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Duloxetine discontinuation, now 15mg, tapering from 60mg during last 30 days, switching to low dose venlafaxine?(because of severe withdrawal symptoms).

Duloxetine discontinuation, now 15mg, tapering from 60mg during last 30 days, switching to low dose venlafaxine?(because of severe withdrawal symptoms).

Both are SNRI: Gradually tapering off is the right formula for snri discontinuation. Venlafaxine is the same group snri anti-depressant. Venlafaxine has a good efficiency and safety record. However, you should know that discontinuation can lead to venlafaxine withdrawal syndrome. ...Read more

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Is it normal to have withdrawal symptoms when getting off duloxetine?

No: In my experience discontinuance (not withdrawal) symptoms r less frequent and not as severe--they r very common with Effexor (venlafaxine) and Paxil on the other hand. ...Read more

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How long do nicotine withdrawal symptoms last?

How long do nicotine withdrawal symptoms last?

Days to weeks: Several days to several weeks depending on how much and how long the use has been and how sudden the cessation of use. ...Read more

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How long do trazadone withdrawal symptoms last?

How long do trazadone  withdrawal symptoms last?

Trazodone: It is very unusual to have withdrawal symptoms with trazodone. It is an mild antidepressant which is used at bedtime because its sedative effect, improving sleep as well as replenishing neurotransmitters involved in depression. If anything, you will find that causes headaches and vivid dreams in the first week of using it. It is not addictive. ...Read more

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How long do the withdrawal symptoms of paroxetine last?

How long do the withdrawal symptoms of paroxetine last?

Depends: Some people, for reasons that are not clear, are more sensitive to changes in serotonergic medications such as paroxetine (paxil) and suffer from discontinuation symptoms. In my experience, the way to manage this is to very slowly taper off the medication. Depending on the dose and duration of treatment, that can take many months (and often a lot of tab splitting and quartering). ...Read more