Doctor insights on:
How Long Do Corticosteroids Remain In Your System
Days to weeks: Corticosteroids are made naturally in our bodies and are involved in the regulation of inflammation. Because of this, all cells in our bodies have receptors for these compounds. When a corticosteroid is prescribed (topical, oral, or by injection), how long it remains is dependent on how quickly it is metabolized. Usually corticosteroids are metabolized in days but occasionally in weeks.See 1 more doctor answer
Depends: Depends upon formulation, dose and route of administration. Oral is 1-2 days, with higher doses taking slightly longer. Iintramuscular shots (particularly depot form) can take much longer depending on which steroid you've received and the dose. Your doctor should be able to tell you.See 1 more doctor answer
Can long term use of corticosteroid cream affect your endocrine system, and reproductive hormone levels?
Yes: It depends on the strength of the steroid. 1% Hydrocortisone is unlikely to cause any side effects on your adrenal glands, but more powerful creams can have systemic effects.
How safe is alloderm for people suffering from auto-immune diseases? I am suffering from myasthenia gravis for a long time now. I am on a moderate dose of corticosteroids for my condition. I know that they suppress the immune system and also slow down hea
Alloderm: Alloderm is a processed human skin graft which results in an acellular dermal matrix which can be used for a variety of purposes, including treatment of wounds, reconstructive surgery and hernia repairs. Unlike allograft skin grafts (i.e. Skin from another human), which are eventually rejected, the proprietary processing technique retains the normal collagen bundling and intact basement membrane complex of skin, but without the components (skin and connective tissue cells) that cause an immune reaction. In one study (wainwright dj: use of an acellular allograft dermal matrix (alloderm) in the management of full-thickness burns. Burns. 1995 jun;21 (4):243-8) alloderm was used in burn patients and the patients did not demonstrate a specific immune response, either by histology or immunologically. In addition, in your case, the use of corticosteroids would blunt any immune reaction, minimizing the possibility of an immune reaction. This would howver, slow down the healing process, due to the effect of corticosteroids on wound healing.See 1 more doctor answer
What effect, if any, might a corticosteroid injection have on the digestive system and gut bacteria?
Probably not much: Although corticosteroids certainly have an effect on the stomach and surely can affect the gut flora in some way, it is doubtful that one injection would have much of an effect. In addition, it would be difficult to judge what that effect would be, if it did occur. It's a question that is almost impossible to answer without knowing more detail. Good luck.
Not sure: The white blood cell count may increase within 3-4 hours of taking corticosteroids. I am not sure that there is an accurate time for the decrease. Much of it would depend on how long acting the steroid is.
Doubtful.: Corticosteroids can lead to sodium and fluid retention by the kidneys, but with long-term use, a "steady state" is reached and ongoing fluid weight gain may occur but should not be sudden. Sudden fluid weight gain should be evaluated by a physician who knows your history better and can perform a physical exam. Best of luck!
After corticosteroids at 8 locations of my iliopsoas I have 55% better. Still difficult to sit for long. Its been 11 days now. Can it worsen again?
Yes: This is very difficult problem to solve and occasionally the symptoms do come back the injections help decrease the inflammation of the tendon and are temporary in nature once the medicine is absorbed and you do not strengthen the muscle it is possible for the irritation to come back hopefully your symptoms will continue to improve follow the recommendations from your doctor and strengthen the mus.
Eczema: Topical corticosteroids should take a couple of days to see improvement of your skin, but relief from the itching should improve within a couple of hours. You should work to keep your skin well hydrated with hypoallergenic lotion through out the day, likely applying lotion more than three times. This will allow you to limit using the steroids. If extensive eczema, see a Dermatologist for more careSee 1 more doctor answer
Time\and Dose!: We gradually decrease the dose, but my answer may not fit because I don't know your dose and time on it. Generally, if a person is on 20mg/day, we go with 20/15 every other dayfor one week, 20/10 the next, 20/5 the next, then 10/5 and finally 10/0. If you do a taper like this, no problems should ensue. Unless there is a serious need to be on the medication. Check with the dr. Who gave you the rx.
How long does it generally take for one's body/hormones to regulate after going off a corticosteroid that has been used for the past 4 years?
Not much: So long steroids were tapered right, you might need still stress dosing if going through surgery or if you acquire severe infection for some time after stopping the steroids, more important though are the other effects of steroids on your body, especially eyes and bones, also your blood pressure, and your blood sugar metabolism, you need to keep following with your doctor, and endocrinologist
"using corticosteroids long enough, takes time to ramp up corticosteroid production" - I have used advair 250/50 for 1.5 months, can I go cold turkey?
How long should corticosteroid joint injections last? Had in april and rheumo thinks my daughter should get again
3 months, but: 3 months, but injections don't treat the underlying disease. If recurrent need, other treatments may be better.See 1 more doctor answer
I have atopic dermatitis for a long time. Isn't there a long term solution for this? I am mostly using oinments including corticosteroids.
A few months: Your body makes the equivalent of 12 mg of Prednisone daily. Once the amount of Prednisone you are taking is less than that, say 10 mg, your moon facies should begin to resolve. It should go away faster if you are completely weaned off Prednisone as opposed to remaining on a low dose. Figure 3-12 months depending on individual variation but it will happen.
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