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Doctor insights on: How Long After Birth Does A Child Who Inherited Thalassemia Major Show Symptoms

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How long after birth does a child who inherited thalassemia major show symptoms?

How long after birth does a child who inherited thalassemia major show symptoms?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Dr. James Ball
78 doctors shared insights

Hemolytic Anemia (Definition)

Hemolytic anemia is where red blood cells are destroyed too quickly. There are many possibilities that would cause this rbc breakdown. Antibodies, abnormal rbc membranes (spherocytosis), abnormal hemoglobins (sickle cell, thalassemia), abnormal rbc enzymes. If hemolytic anemia is is suspected, many tests may be ordered ...Read more


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After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

9-12 months old: Children with beta-thalassemia major usually demonstrate no initial symptoms until the later part of the first year of life (when beta chains are needed to pair with Alpha chains to form hemoglobin (hb) a, after gamma chains production is turned off). ...Read more

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My child is suffering from thalassemia major & advised for a spleen removal operation after few weeks, is this normal?

My child is suffering from thalassemia major & advised for a spleen removal operation after few weeks, is this normal?

Thalassemia Major: Treatment for thalassemia major often involves regular blood transfusions and folate supplements. If you receive blood transfusions, you should not take iron supplements. Doing so can cause a high amount of iron to build up in the body, which can be harmful. Persons who receive significant numbers of blood transfusions need a treatment called chelation therapy to remove excess iron from the body. ...Read more

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What are the symptoms of thalassemia major?

What are the symptoms of thalassemia major?

See below: The most severe form of Alpha thalassemia major causes stillbirth (death of the unborn baby during birth or the late stages of pregnancy). Children born with thalessemia major (cooley's anemia) are normal at birth, but develop severe anemia during the first year of life. Other symptoms can include: •bone deformities in the face •fatigue •growth failure •shortness of breath •yellow skin. ...Read more

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What are the most common symptoms of beta-thalassemia major?

What are the most common symptoms of beta-thalassemia major?

Anemia symptoms: The symptoms of beta thalassemia major are those of severe anemia, which include weakness, pallor (pale appearance), decreased growth/development, rapid heart rate, exercise intolerance, thickened bones as the marrow enlarges to try to make more blood cells, enlarged spleen, etc... ...Read more

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Could a person on their 20's have any chance of living with beta thalassemia major?

Could a person on their 20's have any chance of living with beta thalassemia major?

Yes: It's a horrible disease but the newer remedies are helping these folks live longer and better. ...Read more

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Is there is any cure for thalassemia major?

Bone marrow transpla: The only present cure for thalassemia major is through bone marrow transplant. This delicate procedure is quite risky even in he best hands but can be life saving if a donor match is found. ...Read more

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What if a patient with thalassemia major starts to have a high bilirubin?

What if a patient with thalassemia major starts to have a high bilirubin?

Several reasons: Many patients with thalassemia will have elevated bilirubin from the start. This can be made worse here and there from certain experiences which cause the body to breakdown blood cells more rapidly (infection, new medications). Also, if the bilirubin has been climbing, i would check the health of the liver. This can be done with blood tests, mris and possibly biopsies. ...Read more

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Is beta thalassemia major andd hb e/beta thalassemia same?

Is beta thalassemia major andd hb e/beta thalassemia same?

Not the same.: Hemoglobin e is found in the asian population frequently and may be seen with thal trait. Thal major is a serious problem requiring much intervention, including transfusions and frequently splenectomy. Your doctor should be your guiding you. Pregnancy needs to be discussed with your doctor. ...Read more

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Dr. Michael Engel
261 doctors shared insights

Thalassemia (Definition)

Thalassemia is a genetic condition in which the oxygen carrying hemoglobin molecule is altered by genetic mutations. This leads to symptoms of anemia include fatigue, pallor, ...Read more


Placenta (Definition)

The placenta is an organ that connects the developing fetus to the uterine wall to allow nutrient uptake, waste elimination, and gas exchange via ...Read more