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Doctor insights on: How Long After Birth Does A Child Who Inherited Thalassemia Major Show Symptoms

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How long after birth does a child who inherited thalassemia major show symptoms?

How long after birth does a child who inherited thalassemia major show symptoms?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

Thalassemia is sever anemia,it ...Read more


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After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

After how much time does the child suffering from thalassemia major show symptoms of disease after birth?

6-8 months for beta: Alpha thalassemia major is generally fatal before birth, with just rare cases born alive. Beta thalassemia major babies look normal at birth because fetal hemoglobin doesn't need beta globulin. As fetal hemoglobin goes away and adult hemoglobin starts being made, the baby will feel the effects of his lack of beta globulin. Symptoms start after the first 6-8 months of life. ...Read more

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Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

Following how much time does the child suffering from thalassemia major show symptoms of disease after birth?

9-12 months old: Children with beta-thalassemia major usually demonstrate no initial symptoms until the later part of the first year of life (when beta chains are needed to pair with Alpha chains to form hemoglobin (hb) a, after gamma chains production is turned off). ...Read more

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My child is suffering from thalassemia major & advised for a spleen removal operation after few weeks, is this normal?

My child is suffering from thalassemia major & advised for a spleen removal operation after few weeks, is this normal?

Thalassemia Major: Treatment for thalassemia major often involves regular blood transfusions and folate (folic acid) supplements. If you receive blood transfusions, you should not take iron supplements. Doing so can cause a high amount of iron to build up in the body, which can be harmful. Persons who receive significant numbers of blood transfusions need a treatment called chelation therapy to remove excess iron from the body. ...Read more

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What are the most common symptoms of beta-thalassemia major?

What are the most common symptoms of beta-thalassemia major?

Anemia symptoms: The symptoms of beta thalassemia major are those of severe anemia, which include weakness, pallor (pale appearance), decreased growth/development, rapid heart rate, exercise intolerance, thickened bones as the marrow enlarges to try to make more blood cells, enlarged spleen, etc... ...Read more

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What are the symptoms of thalassemia major?

See below: The most severe form of Alpha thalassemia major causes stillbirth (death of the unborn baby during birth or the late stages of pregnancy). Children born with thalessemia major (cooley's anemia) are normal at birth, but develop severe anemia during the first year of life. Other symptoms can include: •bone deformities in the face •fatigue •growth failure •shortness of breath •yellow skin. ...Read more

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Could a person on their 20's have any chance of living with beta thalassemia major?

Could a person on their 20's have any chance of living with beta thalassemia major?

Yes: It's a horrible disease but the newer remedies are helping these folks live longer and better. ...Read more

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Is there is any cure for thalassemia major?

Bone marrow transpla: The only present cure for thalassemia major is through bone marrow transplant. This delicate procedure is quite risky even in he best hands but can be life saving if a donor match is found. ...Read more

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If a thalassemia major patient married a normal guy, will the thalassemia be passed down?

If a thalassemia major patient married a normal guy, will the thalassemia be passed down?

If the partner...: ...Has thalassemia trait or another hemoglobin disease, the child can be anemic. Otherwise the child will probably have thalassemia trait or thalassemia minor - not actually sick, but capable of having affected children with another carrier. ...Read more

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Can thalassemia minor change into thalassemia major?

No: Thalassemia minor is a heterozygous condition and thalassemia major is homozygous and a person is born with the defect. One does not turn into the other. ...Read more