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Doctor insights on: How Late In Leukemia Can A Bone Marrow Transplant Be Helpful

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When in leukemia can a bone marrow transplant be helpful?

When in leukemia can a bone marrow transplant be helpful?

Any time: We have learned that offering a transplant earlier, when a patient does not respond to therapy or has a relapse is better because there are less complications but at times this may be the only option left. If your doctors and specifically the stem cell transplant team feel this is the best option, they will offer a transplant for your disease. ...Read more

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Dr. Amrita Dosanjh
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more


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How far along in leukemia can a bone marrow transplant be helpful?

Balancing act: Certainly one wants to try standard therapy first in most cases because it has less complications. If this approach is unsuccessful or the patient is very high risk, transplant is considered. The decision to go forward is complicated by such things as the patient's performance status, their prior treatments and the amount of disease. These way into the final decision of when it can be helpful. ...Read more

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A match for bone marrow transplant? A distant relative needs a bone marrow transplant. How can I find out if i'd be a match?

A match for bone marrow transplant? A distant relative needs a bone marrow transplant. How can I find out if i'd be a match?

Short answer: Hla. Human leukocyte antigens (hla) are proteins — or markers — found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not. A close hla match between patient and donor is the most important factor in selecting the best bone marrow donor for a patient. ...Read more

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How often does a bone marrow transplant not help with leukemia?

How often does a bone marrow transplant not help with leukemia?

It depends.: The risk of relapse depends on a number of factors, such as whether the patient is in remission, the type of leukemia, and pre-transplant prognostic factors. It also depends upon whether the transplant is autologous (from themselves as donor) or allogeneic (from someone else). The relapse risk can be from modest to almost certain depending on these factors. ...Read more

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How can a bone marrow transplant affect a person with hodgkins lymphoma?

How can  a bone marrow transplant affect a person with hodgkins lymphoma?

It is potentially cu: Using bone marrow transplant to treat hodgkin disease is commonly done procedure and has high success rate. It is typically done in patients who do not achieve good results with first line of chemotherapy.It is a curative procedure in more than half of such patients. ...Read more

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How soon after a bone marrow biopsy could the diagnosis of leukemia be made?

How soon after a bone marrow biopsy could the diagnosis of leukemia be made?

Depends / 1 week: It depends. If the bone marrow is "packed" with cancer cells it may be obvious on an initial review by a hematologist and/or hematopathologist. However, for a new diagnosis i generally tell patients it may potentially be a week for special stains/studies and "send out" studies to fully characterize the bone marrow. ...Read more

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Can a patient with lymphoma recover by having a bone marrow transplant?

Can a patient with lymphoma recover by having a bone marrow transplant?

Recover?: What do you mean by recover? A bone marrow or stem cell transplant can be part of the therapy for lymphomas. For some types of lymphoma it can help improve the chances of curing the cancer. It's role is depedent on many factors that would need to be discussed with an oncologist. ...Read more

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Does a woman with acute leukemia and pregnant need a narrow bone transplant?

Does a woman with acute leukemia and pregnant need a narrow bone transplant?

Probably not: Acute leukemia needs to be treated with chemotherapy but not all patients with acute leukemia need a bone marrow or stem cell transplant. Pregnancy may impact the drugs used and the timing of treatment but will not impact whether a bone marrow transplant is needed. ...Read more

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I have leukemia. How painful is a bone marrow transplant?

I have leukemia. How painful is a bone marrow transplant?

The procedure is not: The actual BM transplant (infusion of cells) is not at all painful. There may be some reactions during infusion such as chills, rigors, fever and others but pain is not common. However, there may be significant discomfort from the effects of chemotherapy and/or radiation that may result in severe mucositis (irritation of the lining of mouth, upper airway and swallowing tube) lasting few weeks. ...Read more

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What outcome can I expect from a bone marrow transplant? What is the success rate for bone marrow transplants?

BMT: It depends upon underlying condition for which sct (stem cell or bone marrow transplant) is being performed. Broadly speaking sct can work more than 50% time. ...Read more

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How do you treat a bk virus in a bone marrow transplant patient?

Adjust immune meds: We don't have much options when it comes to bk virus - it doesn't cause much robles except when it comes to transplants. The simplest solution most teams will consider attempting, is to adjust the medications used for immunosuppression - however, this will be weighed against the risk of the organ being rejected. Hope this explanation helps! ...Read more

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Could you tell me what happens when a bone marrow transplant is needed for chronic myeloid leukemia?

This is : By definition a failure of the tyrosine kinase inhibitors. If the patient is chronic phase the curability with transplant should still be about 60%. ...Read more

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How often could a bone marrow transplant not make leukemia go away?

How often could a bone marrow transplant not make leukemia go away?

Highly dependent: On the specific details, but in high risk situations the relapse rate can be as high as 80%. ...Read more

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What can doctors find in a bone marrow aspirate?

Cell status: Bone marrow aspiration is used to evaluate the blood cells within the bone marrow, as well as structure. They are performed in conjunction with a complete blood count (CBC) and blood smear to provide info about the health of the bone marrow and capability for blood cell production. The bone marrow is also the reservoir for tumor cells breaking off the primary lesion and entering circulation. They can remain there for many years finally being released where they then travel to a metastatic site. ...Read more

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Can stem cells be used as a substitute for a bone marrow transplant?

Let me clarify: Stem cells are the mother cells. For blood formation the stem cells reside in the bone marrow but they also circulate in the blood. In the old days we took the stem cells out of the bone marrow with needles. Now we can spin the blood(from a vein) and take th stem cells out and use them for transplants to make new blood. This is stricly for creating new blood cells. But each organ has its stem cell. ...Read more

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Can a bone marrow transplant change your blood?

Yes: Your blood will then be formed by stem cells given to you from the donor...So your blood will be the same as the donor's blood. ...Read more

Dr. Keith Stockerl-Goldstein
109 doctors shared insights

Bone Marrow Transplant (Definition)

This refers to using chemotherapy and/or radiation therapy to treat patients and then replacing their bone marrow cells with their own stem cells (autologous transplant) or a donors stem cells (allogeneic transplant). Bone marrow transplant generally refers to using bone marrow cells but is often used when using stem cells collected ...Read more


Bone Marrow (Definition)

Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more