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Doctor insights on: How Is The Blood Affected In A Patient With Acute Lymphocytic Leukemia

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How is the blood affected in a patient with acute lymphocytic leukemia?

How is the blood affected in a patient with acute lymphocytic leukemia?

Different ways: Although the word leukemia refers to cancerous white cells in the blood, many times the disease is growing so fast in the bone marrow that these cells never enter the blood and also, since they crowd out normal blood cells in the marrow, these are also decreased or absent in the blood leading to problems with infection, bleeding profound weakness. ...Read more

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Dr. Liawaty Ho
1,098 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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Could you tell me what happens in the blood in a patient with acute lymphocytic leukemia?

Could you tell me what happens in the blood in a patient with acute lymphocytic leukemia?

See below...: Usually the WBC (white blood cell) count is significantly increased and continues to increase if the leukemia is left untreated. Anemia (low rbc count and hemoglobin) and thrombocytopenia (low platelets) are also common findings. The leukemic cells traveling in the blood may infiltrate various organs. Very high WBC counts may cause increased viscosity of the blood resulting in thrombosis (clot). ...Read more

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What is happening in the blood in a patient with acute lymphocytic leukemia?

What is happening in the blood in a patient with acute lymphocytic leukemia?

Blood abnormal: The lymphoblast count (leukemic cells) increases, anemia and thrombocytopenia (low platelets) develop. This is all due to uncontrolled proliferation of lymphoblasts in the bone marrow. Rapid treatment is required. ...Read more

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If a young child is diagnosed with acute lymphocytic leukemia why is the infection a problem when her WBC is counted?

If a young child is diagnosed with acute lymphocytic leukemia why is the infection a problem when her WBC is counted?

ALL infection risk: Patients with leukemia are at risk for life threatening infections throughout their treatment. At diagnosis, the WBC count may be low, normal or high, but regardless, the wbcs they have are the leukemia cells, which have not matured enough to work properly. Plus the marrow infiltration can prevent other types of wbcs from being produced. Drugs we use to treat leukemia also suppress immune function. ...Read more

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My friend found out she has acute lymphocytic leukemia today. What can she expect?

Chemotherapy: All is generally curable in children, less so in adults. See this site for more info. http://www.mayoclinic.com/health/acute-lymphocytic-leukemia/ds00558. ...Read more

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Can there be a set karyotype for acute lymphocytic leukemia?

Can there be a set karyotype for acute lymphocytic leukemia?

No. : Gross structural changes in chromosome number and structure can be identified by karyotype. There are many such changes associated with all development, yet many all patients have normal karyotypes. This doesn't mean mutations are absent. Modern techniques let us see changes across the genome at single nucleotide resolution. The critical role of epigenetic change is now also firmly established. ...Read more

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What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

Types of cells: White blood cells are different with different mechanisms to pretect body from infections. Acute myeloid leukemia arise from a type of white cells called myeloid series or neutophils, cut lymphoblastic leukemiaa arise from lymph type of white cells. These two types of leukemia have different treatments and the outcome or expectations are very different, none is better than the other in general. ...Read more

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My white blood cell count was 365000 when i was diagnosed with acute lymphoblastic leukemia (2012), how long would I have lived without treatment?

My white blood cell count was 365000 when i was diagnosed with acute lymphoblastic leukemia (2012), how long would I have lived without treatment?

Not long: Hope you get a long-term cure, and glad it was picked up. The acute leukemias are chaotic systems and it's impossible to predict when death may come. The actual white count is immaterial, while a very low platelet count may result in a fatal hemorrhage at an unpredictable time and organ involvement unrelated to lab values can do the same. ...Read more

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Help! what is acute lymphocytic leukemia in a chronic stage?

Help! what is acute lymphocytic leukemia in a chronic stage?

I believe you have: These diagnoses confused. Chronic leukemias display an elevated # of wbcs with morphologic and functional features similar to the mature cells of that lineage (lymphoid-cll vs myeloid-cml). Think of it as not turning off the spigot when the bucket is full. Acute leukemias have features of immature cells for a lineage (aml vs all). Acute leukemias can arise from chronic ones. This is blast crisis. ...Read more

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What is a karyotype for acute lymphocytic leukemia?

What is a karyotype for acute lymphocytic leukemia?

A karyotype is ...: A technique that lets us see the gross structural features of the chromosomes in a cell. Cells are forced to enter mitosis but then are arrested in metaphase with a drug called nocodazole. The chromosomes can the be seen under the microscop which lets is see their number and structure. All cells can have multiple abnormalities that can be seen by karyotype, but may be normal as well. ...Read more

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Dr. Michael Engel
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Acute Lymphoblastic Leukemia (Definition)

Leukemias are those that are immediately life threatening if left untreated. The most common in children is the lymphoid t ype, ie arising from lymphocytes. In adults the myeloid ...Read more