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How Is Polycystic Kidney Disease Inherited
See below: Polycystic kidney disease is a inherited disease in which fluid filled cavities ranging from microscopic to larger sizes upto 10-15 cm occur in the kidneys, causing them to grow very big and loose function. The patients may have no symptoms or present with blood in urine and sometimes kidney pain.Besides controlling high blood pressure there is no definitive treatment yet.Many studies are ongoing. ...Read more
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
It is different: It usually is more serious than the autosomal dominant disease since it needs inheritance from both parents to be expressed i.e. Both genes are affected. It accordingly gets expressed at an earlier age in life. The longer duration of polycystic disease is a factor in predicting dialysis need. ...Read moreSee 1 more doctor answer
Inherited disease.: Polycystic kidney disease is an inherited disorder of the kidneys, where numerous numbers of cysts form throughout both, making them appear large & irregular. It is estimated to affect 1 in every 1000. Many cases are clinically silent, & the diagnosis is usually made with ultrasound though definitive diagnosis is made with genetic testing. Long term, hypertension & kidney failure are consequences. ...Read moreSee 1 more doctor answer
Totally unrelated: Apart from the word connection these are totally unrelated conditions. Having 1 does not lead to the other. Polycystic ovarian syndrome (pcos) is a complex disorder affecting the ovaries which may cause irregular cycles, fertility or metabolic problems. Polycystic kidney disease is genetic disorder and comes in two versions, both causing kidney problems, which may end in kidney failure / dialysis. ...Read moreSee 2 more doctor answers
At birth,not heredit: The former is a congenital but not hereditary disease involving usually one kidney forming a mass of cysts without functioning kidney tissue. Found with prenatal ultrasound. Kidney shrinks and the other kidney assumes its work. The most common form of PKD which is hereditary results in increasing cyst number and size over many years. Other organs have cysts and kidneys fail over many years. ...Read more
Lab tests: Urine should be checked for protein once a year with a test for microscopic levels of Albumin (often called micro-albumin). Blood should be checked for BUN (blood urea nitrogen) to measure the levels of nitrogen-containing waste levels. Higher levels mean the kidney is not as efficient as it should be. A calculated value called egfr reflects the kidneys' ability to remove waste products. ...Read moreSee 1 more doctor answer
Please help! what is the difference between autosomal dominant and autosomal recessive polycystic kidney disease?
Genes: There are caused by different loci. The recessive form generally causes illness from the time of birth due to the large, ineffective kidneys. The dominant form sneaks up on a person during adult life. The affected kidneys look different in the two diseases. ...Read moreSee 1 more doctor answer
Is there a difference between autosomal dominant and autosomal recessive polycystic kidney disease?
Yes: The dominant form occurs mostly in adults. It is inherited but it takes time to show up as a diagnosable disease in middle to later age. Depending on your luck you either have it from your parent or not( 50% chance).The recessive form could be carried by seemingly healthy persons and when manifests as a disease in the offspring, it shows up at a much earlier age. ...Read more
No: They are separate disorders. Polycystic kidney disease is an inherited disorder due to a specific genetic alteration. In pckd, a small number of patients get cysts in the liver as the only other organ affected. The cause of cysts in the ovaries is a completely different process and they are not related. However, both can occur in the same individual. ...Read more
Yes, but......: Testing for this disease is safe and simple but beware of what you ask for. Knowing that you have polycystic kidney disease will make it difficult or expensive to obtain life and health insurance. Best to get these issues under control first as early diagnosis (before renal insufficiency) offers no benefit. Knowing that you have the gene prior to having children is useful for family planning. ...Read moreSee 1 more doctor answer
Multi vs poly kidney: Multicystic kidney is usually a developmental anomaly of the kidney, usually unilateral and is due to the renal tissue not connecting to the developing urogenital tissue. Usually the kidney does not function, and presents during birth or early childhood. Polycystic kidneys are inherited and usually are functional but eventually will cause progressive renal failure depending on the severity. ...Read moreSee 2 more doctor answers
Polygenic problem: The information that codes for proper heart formation is shared by many genes on chromosomes. Genetic studies show linkage, where a person with a form of chd has a 4% chance of having a first degree relative with any form of chd as well as a 4% risk of having a child with a chd. A few rare syndromes have higher genetic risk (dominant = 50%) that sometimes have chd as part of the syndrome. ...Read more
Usually not: However, the diagnosis if made only on labs may be bogus. A well-muscled man with a high creatinine may be told he has low GFR when he does not. Chronic disease can't be diagnosed except over time. Anyone's kidneys can be temporarily impaired by Motrin. And some loss of kidney function is part of getting older. Best wishes. ...Read moreSee 1 more doctor answer
Mostly not inherited: The vast majority of people with parkinson's seem to get it sporadically, that is without any clear inheritance from family. That being said, we've found around 12 genetic variants that seem to greatly increase the risk of developing pd in some families. Some of them are recessive (rarely crops up), and some are dominant (50% chance of getting it from 1 affected parent). ...Read moreSee 1 more doctor answer
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