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Doctor insights on: How Is Lung Cancer Passed Down In Families

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Is lung cancer passed down in families?

Is lung cancer passed down in families?

Some Types: There is growing evidence that some types of lung cancer can be genetically inherited. These are types of adenocarcinoma that are linked to genetic mutations in a protein called egfr. Often these lung cancers manifest in younger people who are never smokers. ...Read more

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Dr. Barry Rosen
4,363 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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How is breast cancer passed down in families?

How is breast cancer passed down in families?

Familial breast ca: 2 genes are commmonly tested for called brca1 & 2. They are inherited from either male or female lines [not sex-linked], meaning history of breast cancer from both mom & dad's side are important. ...Read more

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Is breast cancer passed down in families even for men?

Is breast cancer passed down in families even for men?

Yes: While most cases of breast cancer are not related to heredity, those that are can be inherited from either parent. Furthermore, a man that harbors this genetic predisposition is at personal risk for breast cancer and can pass this risk to his children. If you have multiple family members with breast cancer, there is a simple blood (brca test) test to determine if you have inherited that risk. ...Read more

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What is the prognosis of lung cancer? My father has a 3.5 inch mass on passage way of lung by aorta of heart but cancer hasn't spread yet.

What is the prognosis of lung cancer? My father has a 3.5 inch mass on passage way of lung by aorta of heart but cancer hasn't spread yet.

Extremely serious: Even in your brief description, you mention 2 worrisome features: size and proximity to the aorta. It's beyond the scope of this forum to speculate on his prognosis, but i think you're aware that your father is in trouble. Talk with his oncologist. There are several types of lung cancer and some are more sensitive to chemotherapy or radiation. Best of luck. ...Read more

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There is rare inherited mutation that gives you 1 in 3 lifetime chance of developing lung cancer even in non smokers. For someone with anxiety and lost mom to bac lung cancer should I test?

There is rare inherited mutation that gives you 1 in 3 lifetime chance of developing lung cancer even in non smokers. For someone with anxiety and lost mom to bac lung cancer should I test?

Which gene?: Egfr t790m's actual risk is unknown since nobody knows how many people without lung cancer carry the mutation. Even li fraumeni doesn't approach a 1/3 risk of lung cancer. And what would you do with this information if you had it? Hopefully you will always be a non-smoker. ...Read more

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Why does atherosclerosis run in families? Is it just a gene that runs through and you just naturally develop cardiovascular disease or is it because of the risk factors that run in families?

Why does atherosclerosis run in families? Is it just a gene that runs through and you just naturally develop cardiovascular disease or is it because of the risk factors that run in families?

Genetics: High cholesterol, high blod pressure and other risks factors are genetically determined and may be responsible for early onsetnheart disease. That said, may risk factors such as obesity or smoking can be modified and lower your overall risk. ...Read more

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My father in law was just diagnosed with stage 4 lung cancer that has spread to the t8 vertebrae and is in the lymph nodes. He only has one kidney due to kidney cancer, he had bladder cancer, has mds, had open heart surgery with 4 bipasses and a heart at

My father in law was just diagnosed with stage 4 lung cancer that has spread to the t8 vertebrae and is in the lymph nodes.  He only has one kidney due to kidney cancer, he had bladder cancer, has mds, had open heart surgery with 4 bipasses and a heart at

What is the question: We need more info. This request says 80 year old Female...is that you or the patient??? Tell us if you have shown this person to an oncologist for treatment consideration. Radiotherapy/ and chemotherapy may be useful but a good medical oncologist is what you need first. Please send us your question(say it clearly) about his lung Cancer(only) ...Read more

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Is there any hope when kidney cancer has spread into the lungs and bone?

Is there any hope when kidney cancer has spread into the lungs and bone?

Stage 4 kidney ca: 5 year survival rate for kidney cancer spread to other organs ( st 4) is 0-20%. This has somewhat improved a little with approval of at least 7 new treatments over last few years. Certain characteristics of the patient & the cancer help to categorize patients into low, intermediate & high risk groups for poor survival. ...Read more

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Psychopath traits genetic as in passed down from grandpa the jd?

Psychopath traits genetic as in passed down from grandpa the jd?

Not usually: While many personality traits and both major psychiatric diagnoses (schizophreniz and bipolar disorder) are often mainly genetic, psychopathic behavior traits are usually produced by traumatic experiences, often multiple and/or recurrent that happen during key developmental periods during early, often pre-school years. There may also have been events or exposure to agents leke drugaalcohol, even. ...Read more

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What is the likelyhood of a sudden polyp in gallbladder being cancer after colon cancer in person with lynch syndrome?

What is the likelyhood of a sudden polyp in gallbladder being cancer after colon cancer in person with lynch syndrome?

Low but possible: Cancer of the gallbladder is associated with hnpcc/lynch syndrome but, overall most gallbladder polyps are benign. I would speak with your GI doctor as a cholecystectomy may be advised depending on the size and how long it's been there. ...Read more

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My dad died of cancer that spread from his lip to lymph nodes to lung 47yo, gpa died of prostate cancer 79yo. Any studies linking cancer to genetics?

My dad died of cancer that spread from his lip to lymph nodes to lung 47yo, gpa died of prostate cancer 79yo. Any studies linking cancer to genetics?

There are: There are several cancers that area related to genetics. The are about 5-15% of cancers. The bulk are not. In your case the key question is if your father was a smoker or not. This kind of cancer is not usually related to prostate cancer. The other important thing is that your mother's family history also is equally important as your father's. ...Read more

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How to slow down the growth of cancer cells? (for last stage cancer patient, cancer cells at liver, lung and pelvis. Most critical is liver.)

How to slow down the growth of cancer cells? (for last stage cancer patient, cancer cells at liver, lung and pelvis. Most critical is liver.)

Your Oncologist can: This is a broad question. There are many anticancer drugs that are used to slow cancer cell growth. But they vary in their effectiveness depending on which organ is the source of cancer. Not knowing the details of the history i can not be any more specific. Please pose this question to the treating oncologist. ...Read more

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Can pancreatic cancer run in the family?

Can pancreatic cancer run in the family?

YES: Yes, but rarely. Only about 10% of pancreatic cancers are associated with a hereditary component. For example: hereditary breast ovarian syndrome with mutations in the brca2 gene, hereditary non-poliposis colorectal cancer (hnpcc) and familial pancreatitis. ...Read more

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My uncle has cancer of the of the colon due to poor diet. We have no cancer history in the family but i've been wondering if this is hereditary?

My uncle has cancer of the of the colon due to poor diet. We have no cancer history in the family but i've been wondering if this is hereditary?

Unlikely genetic: Just one member of the family is not enough to call it familial cancer , 75 % of colon cancers has no family history , so don't worry , you are 21 and if no symptoms , 20 years from now go for regular screening colonoscopy , you will be fine. Yes diet plays a roll but unlikely it is the cause of cancer , develop good dietary habits, eat lots of veggies, fruits, less re meat , will be fine. ...Read more

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My relative has metastatic breast cancer, going through the final stages. Is it advisable for her daughter to undergo tests? Is cancer hereditary?

My relative has metastatic breast cancer, going through the final stages. Is it advisable for her daughter to undergo tests? Is cancer hereditary?

Yes, some forms of: Breast cancer are hereditary. It's best to ask your relative's doctor what if she had the genetic type of breast cancer. If your relative got it at a fairly young age, it is definitely advisable for her daughter to get genetic testing. ...Read more

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Can you tell me about the incidence of liver tumor cancer cells and some cells traveling thru the bloodstream when there is early stage cancer?

Can you tell me about the incidence of liver tumor cancer cells and some cells traveling thru the bloodstream when there is early stage cancer?

Unclear Question!: Please give background of why you ahve this question and then ask a simple questions so that we can explain and simplify your query ...Read more

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Mum has lung cancer tumor no change in size and her weight as gone down to 6 stone from 8 stone in 3 mth is this refactory cachexia?

Mum has lung cancer  tumor no change in size and her weight as gone down to 6 stone  from 8 stone in 3 mth is this refactory cachexia?

Probably: Unintended weight loss of the magnitude your described is not a good sign. Please consult this site for more information on this topic. Wish you and your mom, good health. ...Read more

Lung (Definition)

Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more


Genetic (Definition)

From a medical standpoint, "genetic" refers to the potential heritability of various medical conditions. While some conditions are inevitable (at some point in one's life) as a consequence of simple genetic heritability (eg huntington's disease), a large number of medical conditions (including all behaviorial health disorders) are the expressed final pathway of a ...Read more