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Doctor insights on: How Is Cystic Fibrosis Inherited

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In what way is cystic fibrosis inherited?

In what way is cystic fibrosis inherited?

CF is recessive: Cystic fibrosis is a disorder passed thru the genes of both parents, silent in the carrier parent & expressed in the affected kid who has inherited an affected gene from both parents.One mutation(delta 509) is the most common but others occur and variations in intensity do occur. I believe you can have carrier testing to see if u carry a gene, then avoid a starting a pregnancy with another carrier. ...Read more

Dr. William Walsh
990 doctors shared insights

Cystic Fibrosis (Definition)

A genetic disorder of the lungs and digestive tract that causes repeated lung infections and inhibits ...Read more


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What is cystic fibrosis? How is it inherited?

What is cystic fibrosis? How is it inherited?

CF is recessive: Cystic fibrosis is a disorder passed thru the genes of both parents, silent in the carrier parent & expressed in the affected kid who has inherited an affected gene from both parents.One mutation(delta 509) is the most common but others occur and variations in intensity do occur. The defect produces a variety of serious changes primarily in the lungs and digestive tract impairing life. ...Read more

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What is cystic fibrosis? How is it inherited?

What is cystic fibrosis? How is it inherited?

CF is recessive: Cystic fibrosis is a disorder passed thru the genes of both parents, silent in the carrier parent & expressed in the affected kid who has inherited an affected gene from both parents.One mutation(delta 509) is the most common but others occur and variations in intensity do occur. The defect produces a variety of serious changes primarily in the lungs and digestive tract impairing life. ...Read more

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If you were a carrier of cystic fibrosis, how do you test to see if your unborn child has inherited it?

If you were a carrier of cystic fibrosis, how do you test to see if your unborn child has inherited it?

CF: First you need to determine if the father of the baby is also a carrier of the disease as CF is a recessive disease. Therefore both parents need to be carriers and even then there is only a 25% chance the baby is affected. Doing either cvs or amnio can determine if the fetus is affected by cf. If only one parent is a carrier. Screening post natal is recommended. ...Read more

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How can cystic fibrosis affect p.I.E.S development?

How can cystic fibrosis affect p.I.E.S development?

Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US.A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications.Emotional & phys. development depend on severity, time in hospital, complications.Morb. & mort.factors afect emotional,cognitive behavior. ...Read more

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Can someone be diagnose with cystic fibrosis in their 40's?

Can someone be diagnose with cystic fibrosis in their 40's?

As a carrier: Genetic carrier testing: more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more

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I have symptoms of cystic fibrosis. Is it possible to start show the symptoms in my 30's?

Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read more

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I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

Yes: However, usually an adult who is diagnosed so late has usually had chronic problems with cough and "pneumonias". That said i've diagnosed a new case in a 38 year old woman. ...Read more

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What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

Overall 1/3700: Acording to the CF foundation: the overall birth prevalence is 1/3700 . It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000. More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more

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What is cystic fibrosis?

Genetic disorder: It is a genetic disorder characterized by abnormal sodium channels, which affect a great deal of problems including the respiratory and digestive systems. It is most commonly diagnosed in infants failing to gain appropriate weight, and in children who have multiple chronic infections. ...Read more

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Can you die of cystic fibrosis?

Yes but: Yes but with early diagnosis and regular care and adherence to prescribed therapy by a pediatric pulmonologist the long term survival has improved greatly in the past two decades. ...Read more

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What is cystic fibrosis exactly?

What is cystic fibrosis exactly?

Inherited disease: Cystic fibrosis (CF) is an inherited disease that affects the cells lining the lungs, sinuses, intestines, spleen and liver. It prevents chloride ions from crossing the cell membranes properly. This can clog organ ducts. In the lungs, the extra mucus crushes the cilia and leads to more lung infections. Medications can help; in late-stage disease, lung transplantation may be life-saving. ...Read more

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What is risk of cystic fibrosis?

Depends on genes: The risk of acquiring cystic fibrosis (CF) depends on whether the parents of a child are carriers for the gene. It is estimated that about 1 in 20 americans are carriers of the CF gene. In order for a child to acquire the disease, both parents must be carriers. If both parents are carriers, there is then a 25% chance that the child will acquire the disease. ...Read more

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What exactly is cystic fibrosis?

Cystic fibrosis: CF is a genetic disease that from birth causes the body to produce a thick and sticky mucus. This mucus interferes with the ability to breath and digest food. It is life threatening, but with good management people can live into their 40s and beyond with it. ...Read more

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Can you die from cystic fibrosis?

Yes.: Although the complications of cystic fibrosis are treatable, and although the available treatments are helpful, the disorder shortens the normal life expectancy. ...Read more

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Cystic fibrosis, is it sexlinked?

Autosomal recessive.: Cystic fibrosis (CF) is not sex-linked, but autosomal recessive. That means both parents can be silent carriers--totally unaware--then each passes down this recessive (inactive) gene to their child. This child develops CF because both copies of the formerly inactive gene (1 from each parent) now have no genetic "brake" (normal dominant gene) to prevent the CF gene from expressing itself. ...Read more

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What are symptoms of cystic fibrosis?

Cough, poor growth: Common symptoms of cystic fibrosis include cough, wheeze, recurrent lung infections, poor growth, foul smelling stools, salty sweat, clubbing, and rectal prolapse. The more symptoms the greater the chance of having cystic fibrosis. Most infants today are diagnosed by newborn screening for CF before they develop any symptoms and early therapy can minimize disease symptoms. ...Read more

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How to tell if I have cystic fibrosis?

Sweat test: The gold standard to diagnose cystic fibrosis is the sweat test, which measures the amount of chloride in the sweat. The test takes a few minutes to an hour and is painless. It is done in specialized clinics and hospitals. ...Read more

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