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Doctor insights on: How Is Amyotrophic Lateral Sclerosis Transmitted In Humans

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How is amyotrophic lateral sclerosis transmitted in humans?

How is amyotrophic lateral sclerosis transmitted in humans?

It is not transmitte: It is not typically a heriditary or infectious disease. No one knows the exact cause. ...Read more

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Dr. Thomas Fiala
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more


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What is amyotrophic lateral sclerosis?

What is amyotrophic lateral sclerosis?

Disease of nervecell: Amyotrophic lateral sclerosis, or als, is a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. Als does not affect the senses (sight, smell, taste, hearing, touch). It only rarely affects bladder or bowel function, or a person's ability to think or reason.The condition slowly gets worse and cause difficulty with breathing muscles. ...Read more

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What is amyotrophic lateral sclerosis (als)? 

Motor neuron disease: A disorder of misfolded proteins, attacking nerve cell bodies in spinal cord and brain. Tends to involve weakness not numbness, and can affect legs and arms with flickering of muscles, loss of muscle mass, and evenually problems with breathing and swallowing. Unfortunately, there is no cure, and it preserves awareness. Gratefully, it is relatively rare. ...Read more

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What exactly is amyotrophic lateral sclerosis?

What exactly is amyotrophic lateral sclerosis?

Lou Gehrig's disease: Als is a disease affecting the nerve cell body, causes weakness, muscle wasting, and fasciculations or fluttering of the muscles. It can affect mobility, swallowing, and breathing. There is no known cure to date, and the prognosis is often very poor. We believe it is a disorder of "misfolded proteins", similar in some ways to alzheimer's and parkinson's, but a far rarer condition, fortunately. ...Read more

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What sort of problem is amyotrophic lateral sclerosis?

What sort of problem is amyotrophic lateral sclerosis?

Lou Gehrig's: Als also known as lou gehrig's disease is a disease of nerves. It is a progressive loss of muscle strength. Initial symptoms are usually muscle weakness or cramps followed by muscle paralysis in later stages. Difficulty breathing and swallowing are common due to the muscle weakness. There is no cure but there are medications to help with symptom management. ...Read more

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What is amyotrophic lateral sclerosis (als)? Can it be treated?

Lou Gehrig's disease: Als is a disease affecting the nerve cell body, causes weakness, muscle wasting, and fasciculations or fluttering of the muscles. It can affect mobility, swallowing, and breathing. There is no known cure to date, and the prognosis is often very poor. We believe it is a disorder of "misfolded proteins", similar in some ways to alzheimer's and parkinson's, but a far rarer condition, fortunately. ...Read more

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Hi doctors, was just wondering what is amyotrophic lateral sclerosis?

Lou Gehrig's disease: Als is a very nasty uncurable disease involving the motor neuron in brain and spinal cord, usually arising in middle to later years of life. It results in a steady deterioration of muscle, with atrophy and fasciculations, possibly eventuating in loss of ability to swallow and breathe. The sole medication on the market which may modestly help is riluzole. ...Read more

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Is amyotrophic lateral sclerosis sex-linked or a chromosomal error?

Is amyotrophic lateral sclerosis sex-linked or a chromosomal error?

ALS: Amyotrophic lateral sclerosis or ALS (lou gehrig's disease) is a central nervous system disease that causes progressive loss of strength and coordination. There are no known risk factors which predispose someone to developing als. Most commonly, the cause is unknown but in about 10% of cases, there is a genetic defect which leads to the problem. ...Read more

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Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more

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Could kids get amyotrophic lateral sclerosis?

Could kids get amyotrophic lateral sclerosis?

Similar : But most childhood illnesses which affect the motor neuron, like als, are quite rare, and more hereditary in origin. A variety of such disorders cause weakness in very young children, and adolescents and seem similar in outcome. Also, polio used to affect many children but is almost unknown in usa today. ...Read more

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Who first discovered amyotrophic lateral sclerosis?

Charcot: The French Neurologist Charcot is credited with the paper describing ALS as a distinct illness ...Read more

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What are the tests for amyotrophic lateral sclerosis?

Diagnosis: Since we hope to find alternative problems instead of als, we search for possible other diagnoses. The testing includes blood studies, especially for hyperthyroidism, MRI tests of the neck and spinal cord, EMG studies, and even muscle biopsies on occasion. ...Read more

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What are the symptoms of amyotrophic lateral sclerosis?

What are the symptoms of amyotrophic lateral sclerosis?

See below: The main symptoms of ALS are weakness. The weakness often starts with one hand and then may progress to the other. The legs will often become weak as well. The muscles begin to get thinner. This is called atrophy. There may also be exaggerated reflexes and stiffness in the muscles called spasticity. The muscles that help us speak and swallow and breath can also be weakened. ...Read more

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What does it mean when a guy has amyotrophic lateral sclerosis?

Degenrative DO: Als is a neurologic disease where nerves in the central nervous system degenerate, leading to weakness. This can cause inability to walk or use the hands or arms, facial weakness, difficulty eating and swallowing, and respiratory difficulties, leading to infections like pneumonia. It is not a curable disease. ...Read more

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What are the challenges of living with amyotrophic lateral sclerosis?

Very difficult: ALS is a progressive nasty disease with NO cure or even significant control other than Riluzole, and causes muscular atrophy, weakness, fasciculations, and eventual inability to swallow or breathe. As you can imagine, these problems require extensive medical care and diligence, and interventions which may be very complex. ...Read more

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What is the definition or description of: Amyotrophic lateral sclerosis?

Neurodegenerative: ALS is a neurodegenerative disease of the upper and lower motor neurons. There is a male predominance, and occurs most frequently between the ages of 50 - 60 years. While the most frequent form has a dire prognosis, it does have several variants, with different prognoses that can be prolonged with respect to survival. The diagnosis is based on the clinical findings and robust NCV/EMG studies. ...Read more

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What are the main causes of amyotrophic lateral sclerosis? What can be done to treat it?

See below: We really do not understand the cause, but 10% are genetic and 25% of these are associated with mutations of a gene encoding copper/zinc superoxide dismutase. 90% are sporadic and of no clear causation. There is no cure and control measures are mediocre. The drug Riluzole may delay need to respirator, but most treatments are palliative. ...Read more

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Just heard a close neighbor has amyotrophic lateral sclerosis. How do we explain this condition to the kids?

Weakness: I would explain that it means he will get weak over time, may eventually need a wheelchair, and that his doctors will do everything they can to help him. I would tell them they can't catch it from him, and it is a rare condition, so it is unlikely they or their family members would develop it. ...Read more

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What is the treatment for amyotrophic lateral sclerosis?

What is the treatment for amyotrophic lateral sclerosis?

Not good: Lou gehrig's disease remains resistant to successful treatment or control. The drug Riluzole is on the market but is very disappointing, although may delay useage of a tracheostomy tube for a few months. We are learning about a misfolded protein, and this may point the way for future success. ...Read more

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Last advances in the investigation on amyotrophic lateral sclerosis?

Research still slow: A number of established agents have recently been investigated for their potential as neuroprotective agents, including antibiotics and minocycline. Progress has also been made in exploiting growth factors for the treatment of amyotrophic lateral sclerosis, partly due to advances in developing effective delivery systems to the central nervous system but overall out looks so far is not great yet. ...Read more

Dr. Steven Bowers
533 doctors shared insights

Amyotrophic Lateral Sclerosis (Lou Gehrig Disease) (Definition)

Also known as Amyotrophic Lateral Sclerosis (ALS) this is a disorder of the nerve cells in the brain and spinal cord that play a role in controlling voluntary muscle movement. ...Read more